Pathway Analysis for Gaussian Graphical Networks
John Zhuang
2024-06-17
library(multiMiR)## Welcome to multiMiR.
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## default value: http://multimir.org/
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## Database Version: 2.3.0 Updated: 2020-04-15library(clusterProfiler)## ## clusterProfiler v4.12.2 Learn more at https://yulab-smu.top/contribution-knowledge-mining/
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## Please cite:
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## T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan,
## X Fu, S Liu, X Bo, and G Yu. clusterProfiler 4.0: A universal
## enrichment tool for interpreting omics data. The Innovation. 2021,
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## select## library(stringr)
library(ggplot2)0. Loading of Results
A. List of all Gene names in the dataset
gene.names = readRDS("data/derived/unique_gene_names.rds")B. Selected Features
results.ggm= readRDS("data/sel_features/results_ggm_network_stats_all.rds")ggm.RPPA = results.ggm$full_sample$`RPPA Array`$`FDR1e-1`
names.ggm.RPPA = rownames(ggm.RPPA[which(ggm.RPPA$degree > 0),])
ggm.R2Gn.min = results.ggm$full_sample$RNASeq2GeneNorm$`FDR1e-14`
names.ggm.R2Gn.min = rownames(ggm.R2Gn.min[which(ggm.R2Gn.min$degree > mean(ggm.R2Gn.min$degree)),])
ggm.R2Gn.6 = results.ggm$full_sample$RNASeq2GeneNorm$`FDR1e-6`
names.ggm.R2Gn.6 = rownames(ggm.R2Gn.6[which(ggm.R2Gn.6$degree > mean(ggm.R2Gn.6$degree)),])
ggm.mRSG.min = results.ggm$full_sample$miRNASeqGene$`FDR1e-13`
names.ggm.mRSG.min = rownames(ggm.mRSG.min[which(ggm.mRSG.min$degree > mean(ggm.mRSG.min$degree)),])
ggm.mRSG.6 = results.ggm$full_sample$miRNASeqGene$`FDR1e-6`
names.ggm.mRSG.6 = rownames(ggm.mRSG.6[which(ggm.mRSG.6$degree > mean(ggm.mRSG.6$degree)),])
ggm.all.min = results.ggm$full_sample$all$`FDR1e-14`
names.ggm.all.min = rownames(ggm.all.min[which(ggm.all.min$degree > mean(ggm.all.min$degree)),])
ggm.all.6 = results.ggm$full_sample$all$`FDR1e-6`
names.ggm.all.6 = rownames(ggm.all.6[which(ggm.all.6$degree > mean(ggm.all.6$degree)),])
ggm.RPPA.a = results.ggm$by_vital_status$`RPPA Array`$alive$`FDR1e-1`
names.ggm.RPPA.a = rownames(ggm.RPPA.a[which(ggm.RPPA.a$degree > 0), ])
ggm.RPPA.d = results.ggm$by_vital_status$`RPPA Array`$dead$`FDR1e-1`
names.ggm.RPPA.d = rownames(ggm.RPPA.d[which(ggm.RPPA.d$degree > 0), ])
ggm.R2Gn.min.a = results.ggm$by_vital_status$RNASeq2GeneNorm$alive$`FDR1e-14`
names.ggm.R2Gn.min.a = rownames(ggm.R2Gn.min.a[which(ggm.R2Gn.min.a$degree > mean(ggm.R2Gn.min.a$degree)),])
ggm.R2Gn.min.d = results.ggm$by_vital_status$RNASeq2GeneNorm$dead$`FDR1e-14`
names.ggm.R2Gn.min.d = rownames(ggm.R2Gn.min.d[which(ggm.R2Gn.min.d$degree > mean(ggm.R2Gn.min.d$degree)),])
ggm.R2Gn.6.a = results.ggm$by_vital_status$RNASeq2GeneNorm$alive$`FDR1e-6`
names.ggm.R2Gn.6.a = rownames(ggm.R2Gn.6.a[which(ggm.R2Gn.6.a$degree > mean(ggm.R2Gn.6.a$degree)), ])
ggm.R2Gn.6.d = results.ggm$by_vital_status$RNASeq2GeneNorm$dead$`FDR1e-6`
names.ggm.R2Gn.6.d = rownames(ggm.R2Gn.6.d[which(ggm.R2Gn.6.d$degree > mean(ggm.R2Gn.6.d$degree)), ])
#ggm.RR.min.a = results.ggm$by_vital_status$`RPPA + R2Gn`$alive$`FDR1e-14`
#names.ggm.RR.min.a = rownames(ggm.RR.min.a[which(ggm.RR.min.a$degree > mean(ggm.RR.min.a$degree)), ])
#ggm.RR.min.d = results.ggm$by_vital_status$`RPPA + R2Gn`$dead$`FDR1e-14`
#names.ggm.RR.min.d = rownames(ggm.RR.min.d[which(ggm.RR.min.d$degree > mean(ggm.RR.min.d$degree)), ])
#ggm.RR.6.a = results.ggm$by_vital_status$`RPPA + R2Gn`$alive$`FDR1e-6`
#names.ggm.RR.6.a = rownames(ggm.RR.6.a[which(ggm.RR.6.a$degree > mean(ggm.RR.6.a$degree)), ])
#ggm.RR.6.d = results.ggm$by_vital_status$`RPPA + R2Gn`$dead$`FDR1e-6`
#names.ggm.RR.6.d = rownames(ggm.RR.6.d[which(ggm.RR.6.d$degree > mean(ggm.RR.6.d$degree)), ])
ggm.mRSG.min.a = results.ggm$by_vital_status$miRNASeqGene$alive$`FDR1e-13`
names.ggm.mRSG.min.a = rownames(ggm.mRSG.min.a[which(ggm.mRSG.min.a$degree > mean(ggm.mRSG.min.a$degree)),])
ggm.mRSG.min.d = results.ggm$by_vital_status$miRNASeqGene$dead$`FDR1e-13`
names.ggm.mRSG.min.d = rownames(ggm.mRSG.min.d[which(ggm.mRSG.min.d$degree > mean(ggm.mRSG.min.d$degree)),])
ggm.mRSG.6.a = results.ggm$by_vital_status$miRNASeqGene$alive$`FDR1e-6`
names.ggm.mRSG.6.a = rownames(ggm.mRSG.6.a[which(ggm.mRSG.6.a$degree > mean(ggm.mRSG.6.a$degree)), ])
ggm.mRSG.6.d = results.ggm$by_vital_status$miRNASeqGene$dead$`FDR1e-6`
names.ggm.mRSG.6.d = rownames(ggm.mRSG.6.d[which(ggm.mRSG.6.d$degree > mean(ggm.mRSG.6.d$degree)), ])
ggm.all.min.a = results.ggm$by_vital_status$all$alive$`FDR1e-14`
names.ggm.all.min.a = rownames(ggm.all.min.a[which(ggm.all.min.a$degree > mean(ggm.all.min.a$degree)),])
ggm.all.min.d = results.ggm$by_vital_status$all$dead$`FDR1e-14`
names.ggm.all.min.d = rownames(ggm.all.min.d[which(ggm.all.min.d$degree > mean(ggm.all.min.d$degree)),])
ggm.all.6.a = results.ggm$by_vital_status$all$alive$`FDR1e-6`
names.ggm.all.6.a = rownames(ggm.all.6.a[which(ggm.all.6.a$degree > mean(ggm.all.6.a$degree)), ])
ggm.all.6.d = results.ggm$by_vital_status$all$dead$`FDR1e-6`
names.ggm.all.6.d = rownames(ggm.all.6.d[which(ggm.all.6.d$degree > mean(ggm.all.6.d$degree)), ])1. Convert microRNA to genes
Also remove the ending “.R2Gn” and “.RPPA” from gene names.
split.by.omic = function(variable.list) {
out.mRSG = variable.list[startsWith(variable.list, "hsa")]
out.R2Gn = variable.list[endsWith(variable.list, ".R2Gn")]
out.RPPA = variable.list[endsWith(variable.list, ".RPPA")]
out = list("miRNASeqGene" = out.mRSG,
"RNASeq2GeneNorm" = out.R2Gn,
"RPPAArray" = out.RPPA)
out
}multiomics.to.GENES = function(sel.features, full.search = F, table = "validated", drop.miRNA = F) {
multiomics.list = split.by.omic(sel.features)
# Convert miRNASeqGene to target GENE names
# Skipped and returns an empty list instead of the list of select features,
# or if microRNA features are explicitly dropped (drop.miRNA = T).
# (Usually done when the features has only a few miRNA and unable to target any genes)
if (length(multiomics.list[[1]]) > 0 & !drop.miRNA) {
if (!full.search) { # Search only among the 198 genes in ACC, recommended
targets= get_multimir(mirna = multiomics.list[[1]],
target = gene.names,
table = table,
summary = T)
mRSG.target.genes = unique(targets@data$target_symbol)
} else { # Search the full dataset, not recommended.
# Use only if ACC gene search returns nothing or fails.
# Genes not in the ACC genes need to be manually removed.
targets= get_multimir(mirna = multiomics.list[[1]],
table = table,
summary = T)
mRSG.target.genes = unique(targets@data$target_symbol)
}
} else {
mRSG.target.genes = list()
}
#Remove suffix for Pathway Analysis Compatibility
R2Gn.genes = str_remove(multiomics.list[[2]], ".R2Gn")
RPPA.genes = str_remove(multiomics.list[[3]], ".RPPA")
#Join all cleaned-up genes are remove duplicates.
out1 = c(mRSG.target.genes, R2Gn.genes, RPPA.genes)
out = as.character(unique(out1))
out
}geneNames <- list("RPPA"= multiomics.to.GENES(names.ggm.RPPA),
"R2Gn.min"= multiomics.to.GENES(names.ggm.R2Gn.min),
"R2Gn.6"= multiomics.to.GENES(names.ggm.R2Gn.6),
"mRSG.min"= multiomics.to.GENES(names.ggm.mRSG.min),
"mRSG.6"= multiomics.to.GENES(names.ggm.mRSG.6),
"all.min"= multiomics.to.GENES(names.ggm.all.min),
"all.6"= multiomics.to.GENES(names.ggm.all.6),
"RPPA.0" = multiomics.to.GENES(names.ggm.RPPA.a),
"RPPA.1" = multiomics.to.GENES(names.ggm.RPPA.d),
"R2Gn.min.0" = multiomics.to.GENES(names.ggm.R2Gn.min.a),
"R2Gn.min.1" = multiomics.to.GENES(names.ggm.R2Gn.min.d),
"R2Gn.6.0" = multiomics.to.GENES(names.ggm.R2Gn.6.a),
"R2Gn.6.1" = multiomics.to.GENES(names.ggm.R2Gn.6.d),
#"RR.min.0" = multiomics.to.GENES(names.ggm.RR.min.a),
#"RR.min.1" = multiomics.to.GENES(names.ggm.RR.min.d),
#"RR.6.0" = multiomics.to.GENES(names.ggm.RR.6.a),
#"RR.6.1" = multiomics.to.GENES(names.ggm.RR.6.d)
"mRSG.min.0" = multiomics.to.GENES(names.ggm.mRSG.min.a),
"mRSG.min.1" = multiomics.to.GENES(names.ggm.mRSG.min.d),
"mRSG.6.0" = multiomics.to.GENES(names.ggm.mRSG.6.a),
"mRSG.6.1" = multiomics.to.GENES(names.ggm.mRSG.6.d),
"all.min.0" = multiomics.to.GENES(names.ggm.all.min.a),
"all.min.1" = multiomics.to.GENES(names.ggm.all.min.d),
"all.6.0" = multiomics.to.GENES(names.ggm.all.6.a),
"all.6.1" = multiomics.to.GENES(names.ggm.all.6.d)
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## Searching tarbase ...geneNames## $RPPA
## [1] "IGFBP2" "PDCD4" "GAPDH" "FASN" "MYH11" "TFRC" "GATA3" "ATM"
## [9] "TTF1" "G6PD" "AR" "PTEN" "MSH6" "MSH2"
##
## $R2Gn.min
## [1] "GAPDH" "SQSTM1" "FN1" "EEF2" "HSPA1A" "IGFBP2"
## [7] "RPS6" "SYP" "CTNNB1" "TGM2" "CDH2" "CCND1"
## [13] "FASN" "SERPINE1" "PRKCA" "PIK3R1" "TUBA1B" "COL6A1"
## [19] "G6PD" "CDKN1A" "PEA15" "CTNNA1" "PDCD4" "NDRG1"
## [25] "ERBB3" "ANXA1" "ADAR" "TFRC" "YWHAZ" "YWHAB"
## [31] "PXN" "ERRFI1" "EIF4G1" "STMN1" "PIK3R2" "ITGA2"
## [37] "MYH9" "YWHAE" "RAB11A" "PARP1" "KDR" "CDK1"
## [43] "BCL2L1" "CCNB1" "PREX1" "IDH3A"
##
## $R2Gn.6
## [1] "GAPDH" "SQSTM1" "FN1" "HSPA1A" "EEF2" "IGFBP2"
## [7] "SYP" "RPS6" "TGM2" "CTNNB1" "COL6A1" "CDH2"
## [13] "FASN" "SERPINE1" "ERBB3" "PIK3R1" "G6PD" "CDKN1A"
## [19] "PRKCA" "CCND1" "TUBA1B" "PEA15" "ANXA1" "ADAR"
## [25] "PDCD4" "NDRG1" "CTNNA1" "TFRC" "ITGA2" "ERRFI1"
## [31] "PIK3R2" "PXN" "YWHAZ" "MYH9" "DIRAS3" "STMN1"
## [37] "EIF4G1" "YWHAE" "AKT2" "CCNB1" "YWHAB" "PREX1"
## [43] "PRDX1" "AKT1" "CDK1" "ANLN" "SHC1" "JUN"
## [49] "PARK7" "BCL2L1" "KDR" "RAB11A" "FOXM1" "PARP1"
## [55] "ANXA7"
##
## $mRSG.min
## [1] "ESR1" "MET" "BAP1" "ERRFI1" "AKT2" "PTEN"
## [7] "G6PD" "BCL2" "KIT" "NCOA3" "ERBB3" "NF2"
## [13] "KRAS" "NRAS" "RB1" "PDCD4" "MYH9" "PTK2"
## [19] "CCND1" "CDKN1A" "CDKN1B" "IRS1" "MYC" "EGFR"
## [25] "JUN" "PIK3R1" "NOTCH3" "BCL2L11" "EZH2" "RAF1"
## [31] "PTGS2" "ETS1" "STMN1" "SHC1" "FOXO3" "YWHAZ"
## [37] "AKT1" "BCL2L1" "ATM" "STAT5A" "STAT3" "PARP1"
## [43] "XIAP" "CASP8" "CHEK1" "DVL3" "GSK3B" "IGF1R"
## [49] "ITGA2" "MAPT" "YBX1" "PRKAA1" "MAPK8" "PXN"
## [55] "SRSF1" "YWHAE" "ARID1A" "PEA15" "CCNE2" "TUBA1B"
## [61] "BID" "CHEK2" "PRKCD" "RAB25" "PRRT2" "MACC1"
## [67] "ACACA" "E2F1" "HSPA1A" "ADAR" "AXL" "CAV1"
## [73] "MSH2" "CASP3" "CCNE1" "ANXA1" "TFF1" "YAP1"
## [79] "ASNS" "CTNNB1" "EEF2" "EIF4E" "EIF4EBP1" "EIF4G1"
## [85] "FOXM1" "FN1" "GAPDH" "MSH6" "IGFBP2" "PRDX1"
## [91] "PIK3CA" "PRKCA" "MAPK1" "RET" "RPS6" "RPS6KB1"
## [97] "TFRC" "RAB11A" "SQSTM1" "GAB2" "NDRG1" "WWTR1"
## [103] "ANLN" "DIABLO" "NEK7" "RICTOR" "ERCC1" "INPP4B"
## [109] "TP53BP1" "FASN" "BRAF" "LCN2" "RAD50"
##
## $mRSG.6
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "BCL2" "KIT" "NCOA3" "ERBB3"
## [13] "NF2" "HSPA1A" "KRAS" "NRAS" "RB1" "ADAR"
## [19] "PDCD4" "MYH9" "PTK2" "CCND1" "CDKN1A" "CDKN1B"
## [25] "IRS1" "MYC" "EGFR" "JUN" "PIK3R1" "NOTCH3"
## [31] "BCL2L11" "EZH2" "PIK3R2" "RAF1" "PTGS2" "ETS1"
## [37] "STMN1" "SHC1" "FOXO3" "YWHAZ" "AKT1" "VHL"
## [43] "BCL2L1" "ATM" "STAT5A" "STAT3" "PARP1" "XIAP"
## [49] "CASP8" "CDK1" "CHEK1" "CTNNB1" "DVL3" "MTOR"
## [55] "GSK3B" "IGF1R" "ITGA2" "MAPT" "YBX1" "PRKAA1"
## [61] "PRKCA" "MAPK1" "MAPK8" "PXN" "SRSF1" "YWHAE"
## [67] "ARID1A" "BECN1" "PEA15" "CCNE2" "TUBA1B" "EEF2K"
## [73] "AKT1S1" "BID" "CHEK2" "MYH11" "YWHAB" "PRKCD"
## [79] "RAB25" "PRRT2" "MACC1" "ACACA" "E2F1" "AXL"
## [85] "CAV1" "MSH2" "CASP3" "CCNE1" "ANXA1" "TFF1"
## [91] "YAP1" "ASNS" "EEF2" "EIF4E" "EIF4EBP1" "EIF4G1"
## [97] "FOXM1" "FN1" "GAPDH" "MSH6" "IGFBP2" "SMAD4"
## [103] "PRDX1" "PIK3CA" "RET" "RPS6" "RPS6KB1" "TFRC"
## [109] "XRCC1" "RAB11A" "SQSTM1" "GAB2" "NDRG1" "WWTR1"
## [115] "ANLN" "DIABLO" "NEK7" "RICTOR" "ERCC1" "INPP4B"
## [121] "TP53BP1" "FASN" "BRAF" "LCN2" "RAD50"
##
## $all.min
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "BCL2" "KIT" "NCOA3" "ERBB3"
## [13] "NF2" "KRAS" "NRAS" "RB1" "ADAR" "PDCD4"
## [19] "MYH9" "CCND1" "CDKN1A" "CDKN1B" "IRS1" "MYC"
## [25] "EGFR" "JUN" "PIK3R1" "NOTCH3" "BCL2L11" "EZH2"
## [31] "PIK3R2" "RAF1" "PTGS2" "ETS1" "STMN1" "SHC1"
## [37] "FOXO3" "YWHAZ" "AKT1" "BCL2L1" "ATM" "STAT5A"
## [43] "STAT3" "PARP1" "XIAP" "AR" "CASP8" "CDK1"
## [49] "CHEK1" "CTNNB1" "DVL3" "EEF2" "EIF4E" "EIF4G1"
## [55] "GSK3B" "IGF1R" "ITGA2" "MAPT" "YBX1" "PRKAA1"
## [61] "PRKCA" "MAPK1" "MAPK8" "PXN" "RAD51" "SRSF1"
## [67] "TFRC" "YWHAE" "ARID1A" "BECN1" "PEA15" "CCNE2"
## [73] "TUBA1B" "NDRG1" "EEF2K" "DIABLO" "AKT1S1" "BID"
## [79] "ERCC1" "CHEK2" "MYH11" "INPP4B" "YWHAB" "PRKCD"
## [85] "RAB25" "PRRT2" "MACC1" "ACACA" "E2F1" "HSPA1A"
## [91] "PREX1" "AXL" "PTK2" "CAV1" "MSH2" "CASP3"
## [97] "CCNE1" "ANXA1" "TFF1" "YAP1" "ANXA7" "ASNS"
## [103] "EIF4EBP1" "FOXM1" "FN1" "GAPDH" "MSH6" "IGFBP2"
## [109] "SMAD4" "PRDX1" "SERPINE1" "PIK3CA" "RET" "RPS6"
## [115] "RPS6KB1" "XRCC1" "RAB11A" "SQSTM1" "GAB2" "WWTR1"
## [121] "ANLN" "NEK7" "RICTOR" "TP53BP1" "FASN" "BRAF"
## [127] "LCN2" "RAD50" "SYP" "TGM2" "COL6A1" "CDH2"
## [133] "CTNNA1" "DIRAS3" "GATA3" "RBM15" "TTF1" "VHL"
## [139] "TSC1" "ACVRL1"
##
## $all.6
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "BCL2" "KIT" "NCOA3" "ERBB2"
## [13] "ERBB3" "NF2" "HSPA1A" "KRAS" "NRAS" "RB1"
## [19] "ADAR" "PDCD4" "MYH9" "PTK2" "CCND1" "CDKN1A"
## [25] "CDKN1B" "IRS1" "MYC" "EGFR" "JUN" "PIK3R1"
## [31] "NOTCH3" "BCL2L11" "EZH2" "PIK3R2" "RAF1" "PTGS2"
## [37] "ETS1" "STMN1" "SHC1" "FOXO3" "YWHAZ" "AKT1"
## [43] "VHL" "BCL2L1" "ATM" "STAT5A" "STAT3" "PARP1"
## [49] "XIAP" "AR" "CASP8" "CDK1" "CHEK1" "CTNNB1"
## [55] "DVL3" "EEF2" "EIF4E" "EIF4G1" "MTOR" "GSK3B"
## [61] "IGF1R" "ITGA2" "MAPT" "YBX1" "PRKAA1" "PRKCA"
## [67] "MAPK1" "MAPK8" "PXN" "RAD51" "SRSF1" "TFRC"
## [73] "YWHAE" "ARID1A" "BECN1" "PEA15" "CCNE2" "TUBA1B"
## [79] "NDRG1" "EEF2K" "DIABLO" "AKT1S1" "BID" "ERCC1"
## [85] "CHEK2" "MYH11" "INPP4B" "YWHAB" "PRKCD" "RAB25"
## [91] "PRRT2" "MACC1" "ACACA" "SMAD1" "E2F1" "PREX1"
## [97] "AXL" "CAV1" "MSH2" "CASP3" "CCNE1" "ANXA1"
## [103] "TFF1" "YAP1" "ANXA7" "ASNS" "EIF4EBP1" "FOXM1"
## [109] "FN1" "GAPDH" "MSH6" "IGFBP2" "SMAD4" "PRDX1"
## [115] "SERPINE1" "PIK3CA" "RET" "RPS6" "RPS6KB1" "XRCC1"
## [121] "RAB11A" "SQSTM1" "GAB2" "WWTR1" "ANLN" "NEK7"
## [127] "RICTOR" "TP53BP1" "FASN" "BRAF" "LCN2" "RAD50"
## [133] "SYP" "TGM2" "COL6A1" "CDH2" "CTNNA1" "DIRAS3"
## [139] "GATA3" "RBM15" "TTF1" "TSC1" "ACVRL1" "XBP1"
##
## $RPPA.0
## [1] "GAPDH" "G6PD" "IGFBP2" "FASN" "PDCD4" "AR" "MYH11" "PREX1"
## [9] "ATM" "TTF1" "MSH6" "TFRC" "RBM15" "GATA3" "EGFR" "TSC1"
## [17] "IRS1" "MSH2"
##
## $RPPA.1
## [1] "TFRC" "FASN" "GATA3" "GAPDH" "G6PD" "MYH11" "PDCD4" "MSH6"
## [9] "ATM" "RBM15" "ASNS" "PTEN" "MSH2" "IGFBP2" "PEA15" "EGFR"
## [17] "INPP4B" "TSC1" "VHL" "TTF1" "IRS1" "PRDX1" "XBP1" "NF2"
## [25] "PDK1"
##
## $R2Gn.min.0
## [1] "GAPDH" "SQSTM1" "EEF2" "TGM2" "HSPA1A" "IGFBP2"
## [7] "COL6A1" "SYP" "CTNNB1" "CDH2" "FASN" "RPS6"
## [13] "PRKCA" "ANXA1" "G6PD" "NDRG1" "ERBB3" "CTNNA1"
## [19] "SERPINE1" "PDCD4" "FN1" "PIK3R1" "CCND1" "MYH9"
## [25] "PXN" "ERRFI1" "PREX1" "AKT2" "CDKN1A" "YWHAZ"
## [31] "PEA15" "RBM3" "AKT1" "ITGA2" "ADAR" "RAB11A"
## [37] "YWHAB" "TFRC" "PARP1" "DIRAS3" "KDR" "EIF4G1"
## [43] "JUN" "TUBA1B" "STAT5A" "PIK3R2" "XBP1" "NOTCH3"
##
## $R2Gn.min.1
## [1] "FN1" "SYP" "EEF2" "GAPDH" "HSPA1A" "CTNNB1"
## [7] "SQSTM1" "RPS6" "CCND1" "ADAR" "CDH2" "TUBA1B"
## [13] "TFRC" "SERPINE1" "FASN" "CDKN1A" "PEA15" "COL6A1"
## [19] "PIK3R2" "SHC1" "ITGA2" "STMN1" "NDRG1" "AKT1"
## [25] "IGFBP2" "YWHAE" "TGM2" "PXN" "EIF4G1" "PRKCA"
## [31] "PIK3R1" "DIRAS3" "G6PD" "PARK7" "MYH9" "ANXA1"
## [37] "PRKCD" "BAP1" "PDCD4" "JUN" "CCNB1" "DVL3"
## [43] "FOXM1" "ANXA7" "IDH3A"
##
## $R2Gn.6.0
## [1] "GAPDH" "SQSTM1" "IGFBP2" "TGM2" "HSPA1A" "EEF2"
## [7] "COL6A1" "ERBB3" "SYP" "CDH2" "PRKCA" "FASN"
## [13] "CTNNB1" "ANXA1" "RPS6" "PDCD4" "G6PD" "NDRG1"
## [19] "FN1" "PIK3R1" "CTNNA1" "ERRFI1" "SERPINE1" "CCND1"
## [25] "MYH9" "YWHAZ" "PEA15" "PXN" "TFRC" "PARP1"
## [31] "PREX1" "AKT2" "CDKN1A" "EIF4G1" "BCL2L1" "KDR"
## [37] "AKT1" "JUN" "TUBA1B" "PIK3R2" "ITGA2" "YWHAE"
## [43] "RAB11A" "ETS1" "STAT5A" "DIRAS3" "MET" "ADAR"
## [49] "RBM3" "STMN1" "NOTCH3" "YWHAB" "ANXA7"
##
## $R2Gn.6.1
## [1] "FN1" "GAPDH" "SYP" "SQSTM1" "HSPA1A" "EEF2"
## [7] "CTNNB1" "RPS6" "ADAR" "CCND1" "TUBA1B" "CDH2"
## [13] "TFRC" "CDKN1A" "FASN" "SERPINE1" "COL6A1" "PEA15"
## [19] "SHC1" "PIK3R2" "IGFBP2" "ITGA2" "YWHAE" "STMN1"
## [25] "EIF4G1" "NDRG1" "PRKCA" "TGM2" "PXN" "AKT1"
## [31] "DIRAS3" "JUN" "ANXA1" "PCNA" "PDCD4" "MYH9"
## [37] "G6PD" "IDH3A" "PRKCD" "MAPK1" "BAP1" "PARK7"
## [43] "PIK3R1" "RBM3" "ANLN" "CCNB1" "CDK1" "CTNNA1"
## [49] "ANXA7"
##
## $mRSG.min.0
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "BCL2" "KIT" "NCOA3" "ERBB2"
## [13] "ERBB3" "NF2" "KRAS" "NRAS" "RB1" "ADAR"
## [19] "PDCD4" "MYH9" "CCND1" "CDKN1A" "CDKN1B" "IRS1"
## [25] "MYC" "EGFR" "JUN" "PIK3R1" "NOTCH3" "BCL2L11"
## [31] "EZH2" "PIK3R2" "RAF1" "PTGS2" "ETS1" "STMN1"
## [37] "SHC1" "FOXO3" "YWHAZ" "AKT1" "BCL2L1" "ATM"
## [43] "STAT5A" "STAT3" "PARP1" "XIAP" "AR" "CASP8"
## [49] "CDK1" "CHEK1" "CTNNB1" "DVL3" "EEF2" "EIF4E"
## [55] "EIF4G1" "GSK3B" "IGF1R" "ITGA2" "MAPT" "YBX1"
## [61] "PRKAA1" "PRKCA" "MAPK1" "MAPK8" "PXN" "RAD51"
## [67] "SRSF1" "TFRC" "YWHAE" "ARID1A" "BECN1" "PEA15"
## [73] "CCNE2" "TUBA1B" "NDRG1" "EEF2K" "DIABLO" "AKT1S1"
## [79] "BID" "ERCC1" "CHEK2" "MYH11" "INPP4B" "YWHAB"
## [85] "PRKCD" "RAB25" "PRRT2" "MACC1" "ACACA" "SMAD1"
## [91] "E2F1" "HSPA1A" "PREX1" "AXL" "PTK2" "CAV1"
## [97] "MSH2" "CASP3" "CCNE1" "ANXA1" "TFF1" "YAP1"
## [103] "ANXA7" "ASNS" "EIF4EBP1" "FOXM1" "FN1" "GAPDH"
## [109] "MSH6" "IGFBP2" "SMAD4" "PRDX1" "SERPINE1" "PIK3CA"
## [115] "RET" "RPS6" "RPS6KB1" "XRCC1" "RAB11A" "SQSTM1"
## [121] "GAB2" "WWTR1" "ANLN" "NEK7" "RICTOR" "TP53BP1"
## [127] "FASN" "BRAF" "LCN2" "RAD50"
##
## $mRSG.min.1
## [1] "ESR1" "MET" "BAP1" "ERRFI1" "AKT2" "PTEN"
## [7] "G6PD" "BCL2" "KIT" "NCOA3" "ERBB3" "KRAS"
## [13] "NRAS" "RB1" "ADAR" "PDCD4" "MYH9" "CCND1"
## [19] "CDKN1A" "CDKN1B" "IRS1" "MYC" "EGFR" "JUN"
## [25] "PIK3R1" "NOTCH3" "BCL2L11" "EZH2" "PIK3R2" "RAF1"
## [31] "PTGS2" "ETS1" "STMN1" "SHC1" "FOXO3" "YWHAZ"
## [37] "AKT1" "BCL2L1" "STAT5A" "STAT3" "PARP1" "XIAP"
## [43] "AR" "CHEK1" "DVL3" "EIF4E" "EIF4G1" "GSK3B"
## [49] "IGF1R" "ITGA2" "MAPT" "YBX1" "PRKAA1" "PRKCA"
## [55] "MAPK1" "MAPK8" "PXN" "RAD51" "SRSF1" "YWHAE"
## [61] "ARID1A" "PEA15" "CCNE2" "TUBA1B" "NDRG1" "EEF2K"
## [67] "AKT1S1" "BID" "ERCC1" "CHEK2" "MYH11" "INPP4B"
## [73] "YWHAB" "PRKCD" "RAB25" "PRRT2" "ACACA" "E2F1"
## [79] "HSPA1A" "CASP9" "PREX1" "AXL" "PTK2" "CDKN2A"
## [85] "CAV1" "MSH2" "CASP3" "CCNE1" "MAPK9" "ANXA1"
## [91] "TFF1" "YAP1" "ANXA7" "ASNS" "CDK1" "EEF2"
## [97] "EIF4EBP1" "FOXM1" "FN1" "GAPDH" "MSH6" "IGFBP2"
## [103] "SMAD3" "SMAD4" "SERPINE1" "PIK3CA" "MAPK3" "RET"
## [109] "RPS6" "RPS6KB1" "TFRC" "XRCC1" "RAB11A" "SQSTM1"
## [115] "GAB2" "WWTR1" "ANLN" "DIABLO" "NEK7" "RICTOR"
## [121] "TP53BP1" "FASN" "BRAF" "LCN2" "RAD50"
##
## $mRSG.6.0
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "BCL2" "KIT" "NCOA3" "ERBB2"
## [13] "ERBB3" "NF2" "KRAS" "NRAS" "RB1" "ADAR"
## [19] "PDCD4" "MYH9" "CCND1" "CDKN1A" "CDKN1B" "IRS1"
## [25] "MYC" "EGFR" "JUN" "PIK3R1" "NOTCH3" "BCL2L11"
## [31] "EZH2" "PIK3R2" "RAF1" "PTGS2" "ETS1" "STMN1"
## [37] "SHC1" "FOXO3" "YWHAZ" "AKT1" "BCL2L1" "ATM"
## [43] "STAT5A" "STAT3" "PARP1" "XIAP" "AR" "CASP8"
## [49] "CDK1" "CHEK1" "CTNNB1" "DVL3" "EEF2" "EIF4E"
## [55] "EIF4G1" "GSK3B" "IGF1R" "ITGA2" "MAPT" "YBX1"
## [61] "PRKAA1" "PRKCA" "MAPK1" "MAPK8" "PXN" "RAD51"
## [67] "SRSF1" "TFRC" "YWHAE" "ARID1A" "BECN1" "PEA15"
## [73] "CCNE2" "TUBA1B" "NDRG1" "EEF2K" "DIABLO" "AKT1S1"
## [79] "BID" "ERCC1" "CHEK2" "MYH11" "INPP4B" "YWHAB"
## [85] "PRKCD" "RAB25" "PRRT2" "MACC1" "ACACA" "SMAD1"
## [91] "E2F1" "HSPA1A" "PREX1" "AXL" "PTK2" "CAV1"
## [97] "MSH2" "CASP3" "CCNE1" "ANXA1" "TFF1" "YAP1"
## [103] "ANXA7" "ASNS" "EIF4EBP1" "FOXM1" "FN1" "GAPDH"
## [109] "MSH6" "IGFBP2" "SMAD4" "PRDX1" "SERPINE1" "PIK3CA"
## [115] "RET" "RPS6" "RPS6KB1" "XRCC1" "RAB11A" "SQSTM1"
## [121] "GAB2" "WWTR1" "ANLN" "NEK7" "RICTOR" "TP53BP1"
## [127] "FASN" "BRAF" "LCN2" "RAD50"
##
## $mRSG.6.1
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "BCL2" "KIT" "NCOA3" "ERBB3"
## [13] "NF2" "E2F1" "KRAS" "NRAS" "RB1" "ADAR"
## [19] "PDCD4" "MYH9" "CCND1" "CDKN1A" "CDKN1B" "IRS1"
## [25] "MYC" "EGFR" "JUN" "PIK3R1" "NOTCH3" "BCL2L11"
## [31] "EZH2" "PIK3R2" "RAF1" "PTGS2" "ETS1" "STMN1"
## [37] "SHC1" "FOXO3" "YWHAZ" "AKT1" "BCL2L1" "ATM"
## [43] "STAT5A" "STAT3" "PARP1" "XIAP" "AR" "CASP8"
## [49] "CDK1" "CHEK1" "CTNNB1" "DVL3" "EIF4E" "EIF4G1"
## [55] "GSK3B" "IGF1R" "ITGA2" "MAPT" "YBX1" "PRKAA1"
## [61] "PRKCA" "MAPK1" "MAPK8" "PXN" "RAD51" "SRSF1"
## [67] "YWHAE" "ARID1A" "BECN1" "PEA15" "CCNE2" "TUBA1B"
## [73] "NDRG1" "EEF2K" "AKT1S1" "BID" "ERCC1" "ACVRL1"
## [79] "CHEK2" "MYH11" "INPP4B" "YWHAB" "PRKCD" "RAB25"
## [85] "PRRT2" "ACACA" "ERBB2" "HSPA1A" "CASP9" "PREX1"
## [91] "AXL" "PTK2" "CDKN2A" "CAV1" "MSH2" "CASP3"
## [97] "CCNE1" "MAPK9" "ANXA1" "TFF1" "TP53" "YAP1"
## [103] "XBP1" "ANXA7" "ASNS" "EEF2" "EIF4EBP1" "FOXM1"
## [109] "FN1" "GAPDH" "MSH6" "IGFBP2" "SMAD3" "SMAD4"
## [115] "PRDX1" "SERPINE1" "PIK3CA" "MAPK3" "RET" "RPS6"
## [121] "RPS6KB1" "TFRC" "VASP" "XRCC1" "RAB11A" "SQSTM1"
## [127] "GAB2" "WWTR1" "ANLN" "DIABLO" "NEK7" "RICTOR"
## [133] "PTCH1" "TP53BP1" "FASN" "BRAF" "LCN2" "RAD50"
##
## $all.min.0
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "BCL2" "KIT" "NCOA3" "ERBB2"
## [13] "ERBB3" "NF2" "KRAS" "NRAS" "RB1" "ADAR"
## [19] "PDCD4" "MYH9" "CCND1" "CDKN1A" "CDKN1B" "IRS1"
## [25] "MYC" "EGFR" "JUN" "PIK3R1" "NOTCH3" "BCL2L11"
## [31] "EZH2" "PIK3R2" "RAF1" "PTGS2" "ETS1" "STMN1"
## [37] "SHC1" "FOXO3" "YWHAZ" "AKT1" "BCL2L1" "ATM"
## [43] "STAT5A" "STAT3" "PARP1" "XIAP" "AR" "CASP8"
## [49] "CDK1" "CHEK1" "CTNNB1" "DVL3" "EEF2" "EIF4E"
## [55] "EIF4G1" "GSK3B" "IGF1R" "ITGA2" "MAPT" "YBX1"
## [61] "PRKAA1" "PRKCA" "MAPK1" "MAPK8" "PXN" "RAD51"
## [67] "SRSF1" "TFRC" "YWHAE" "ARID1A" "BECN1" "PEA15"
## [73] "CCNE2" "TUBA1B" "NDRG1" "EEF2K" "DIABLO" "AKT1S1"
## [79] "BID" "ERCC1" "CHEK2" "MYH11" "INPP4B" "YWHAB"
## [85] "PRKCD" "RAB25" "PRRT2" "MACC1" "ACACA" "SMAD1"
## [91] "E2F1" "HSPA1A" "PREX1" "AXL" "PTK2" "CAV1"
## [97] "MSH2" "CASP3" "CCNE1" "ANXA1" "TFF1" "YAP1"
## [103] "ANXA7" "ASNS" "EIF4EBP1" "FOXM1" "FN1" "GAPDH"
## [109] "MSH6" "IGFBP2" "SMAD4" "PRDX1" "SERPINE1" "PIK3CA"
## [115] "RET" "RPS6" "RPS6KB1" "XRCC1" "RAB11A" "SQSTM1"
## [121] "GAB2" "WWTR1" "ANLN" "NEK7" "RICTOR" "TP53BP1"
## [127] "FASN" "BRAF" "LCN2" "RAD50" "SYP" "TGM2"
## [133] "COL6A1" "CDH2" "DIRAS3" "CTNNA1" "GATA3" "TTF1"
## [139] "RBM15" "TSC1" "VHL" "ACVRL1"
##
## $all.min.1
## [1] "ESR1" "MET" "BAP1" "ERRFI1" "AKT2" "PTEN"
## [7] "G6PD" "BCL2" "KIT" "NCOA3" "ERBB3" "KRAS"
## [13] "NRAS" "RB1" "ADAR" "PDCD4" "MYH9" "CCND1"
## [19] "CDKN1A" "CDKN1B" "IRS1" "MYC" "EGFR" "JUN"
## [25] "PIK3R1" "NOTCH3" "BCL2L11" "EZH2" "PIK3R2" "RAF1"
## [31] "PTGS2" "ETS1" "STMN1" "SHC1" "FOXO3" "YWHAZ"
## [37] "AKT1" "BCL2L1" "STAT5A" "STAT3" "PARP1" "XIAP"
## [43] "AR" "CHEK1" "DVL3" "EIF4E" "GSK3B" "IGF1R"
## [49] "ITGA2" "MAPT" "YBX1" "PRKAA1" "PRKCA" "MAPK1"
## [55] "MAPK8" "PXN" "RAD51" "SRSF1" "YWHAE" "ARID1A"
## [61] "PEA15" "CCNE2" "TUBA1B" "EEF2K" "AKT1S1" "BID"
## [67] "ERCC1" "CHEK2" "MYH11" "YWHAB" "PRKCD" "RAB25"
## [73] "PRRT2" "ACACA" "E2F1" "HSPA1A" "CASP9" "AXL"
## [79] "PTK2" "CDKN2A" "CAV1" "MSH2" "CASP3" "CCNE1"
## [85] "MAPK9" "ANXA1" "TFF1" "YAP1" "ASNS" "CDK1"
## [91] "CTNNB1" "EEF2" "EIF4EBP1" "EIF4G1" "FOXM1" "FN1"
## [97] "GAPDH" "MSH6" "IGFBP2" "SMAD3" "SMAD4" "PRDX1"
## [103] "PIK3CA" "MAPK3" "RET" "RPS6" "RPS6KB1" "TFRC"
## [109] "XRCC1" "RAB11A" "SQSTM1" "GAB2" "NDRG1" "WWTR1"
## [115] "ANLN" "DIABLO" "NEK7" "RICTOR" "INPP4B" "TP53BP1"
## [121] "FASN" "BRAF" "LCN2" "RAD50" "SYP" "CDH2"
## [127] "COL6A1" "SERPINE1" "TGM2" "GATA3" "ATM" "RBM15"
## [133] "VHL" "NF2" "TSC1" "PREX1" "TTF1"
##
## $all.6.0
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "MAPK14" "BCL2" "KIT" "NCOA3"
## [13] "ERBB2" "ERBB3" "NF2" "KRAS" "NRAS" "RB1"
## [19] "ADAR" "PDCD4" "MYH9" "PTK2" "CCND1" "CDKN1A"
## [25] "CDKN1B" "IRS1" "MYC" "EGFR" "JUN" "PIK3R1"
## [31] "NOTCH3" "BCL2L11" "EZH2" "PIK3R2" "RAF1" "PTGS2"
## [37] "ETS1" "STMN1" "SHC1" "FOXO3" "YWHAZ" "AKT1"
## [43] "BCL2L1" "ATM" "STAT5A" "STAT3" "PARP1" "XIAP"
## [49] "AR" "CASP8" "CDK1" "CHEK1" "CTNNB1" "DVL3"
## [55] "EEF2" "EIF4E" "EIF4G1" "GSK3B" "IGF1R" "ITGA2"
## [61] "MAPT" "YBX1" "PRKAA1" "PRKCA" "MAPK1" "MAPK8"
## [67] "PXN" "RAD51" "SRSF1" "TFRC" "YWHAE" "ARID1A"
## [73] "BECN1" "PEA15" "CCNE2" "TUBA1B" "NDRG1" "EEF2K"
## [79] "DIABLO" "AKT1S1" "BID" "ERCC1" "CHEK2" "MYH11"
## [85] "INPP4B" "YWHAB" "RAB11B" "PRKCD" "RAB25" "PRRT2"
## [91] "MACC1" "ACACA" "SMAD1" "E2F1" "HSPA1A" "PREX1"
## [97] "AXL" "CAV1" "MSH2" "CASP3" "CCNE1" "ANXA1"
## [103] "TFF1" "YAP1" "CDH1" "ANXA7" "ASNS" "EIF4EBP1"
## [109] "FOXM1" "FN1" "GAPDH" "MSH6" "IGFBP2" "SMAD4"
## [115] "NFE2L2" "PRDX1" "SERPINE1" "PIK3CA" "RET" "RPS6"
## [121] "RPS6KB1" "XRCC1" "RAB11A" "SQSTM1" "GAB2" "WWTR1"
## [127] "ANLN" "NEK7" "RICTOR" "TSC2" "TP53BP1" "FASN"
## [133] "BRAF" "LCN2" "RAD50" "TGM2" "SYP" "COL6A1"
## [139] "DIRAS3" "CTNNA1" "CDH2" "RBM3" "GATA3" "TTF1"
## [145] "RBM15" "TSC1" "VHL" "ACVRL1"
##
## $all.6.1
## [1] "ESR1" "AKT2" "BAP1" "ERRFI1" "MET" "PTEN"
## [7] "NOTCH1" "G6PD" "BCL2" "KIT" "NCOA3" "ERBB3"
## [13] "HSPA1A" "KRAS" "NRAS" "RB1" "ADAR" "PDCD4"
## [19] "MYH9" "PTK2" "CCND1" "CDKN1A" "CDKN1B" "IRS1"
## [25] "MYC" "EGFR" "JUN" "PIK3R1" "NOTCH3" "BCL2L11"
## [31] "EZH2" "PIK3R2" "RAF1" "PTGS2" "ETS1" "STMN1"
## [37] "SHC1" "FOXO3" "YWHAZ" "AKT1" "VHL" "BCL2L1"
## [43] "ATM" "STAT5A" "STAT3" "PARP1" "XIAP" "AR"
## [49] "CASP8" "CDK1" "CHEK1" "CTNNB1" "DVL3" "EIF4E"
## [55] "EIF4G1" "MTOR" "GSK3B" "IGF1R" "ITGA2" "MAPT"
## [61] "YBX1" "PRKAA1" "PRKCA" "MAPK1" "MAPK8" "PXN"
## [67] "RAD51" "SRSF1" "YWHAE" "ARID1A" "BECN1" "PEA15"
## [73] "CCNE2" "TUBA1B" "NDRG1" "EEF2K" "AKT1S1" "BID"
## [79] "ERCC1" "CHEK2" "MYH11" "INPP4B" "YWHAB" "RAB11B"
## [85] "PRKCD" "RAB25" "PRRT2" "MACC1" "ACACA" "E2F1"
## [91] "CASP9" "PREX1" "AXL" "CDKN2A" "CAV1" "MSH2"
## [97] "CASP3" "CCNE1" "MAPK9" "ANXA1" "TFF1" "YAP1"
## [103] "CDH1" "ANXA7" "ASNS" "EEF2" "EIF4EBP1" "FOXM1"
## [109] "FN1" "GAPDH" "MSH6" "IGFBP2" "SMAD3" "SMAD4"
## [115] "PRDX1" "SERPINE1" "PIK3CA" "MAPK3" "RET" "RPS6"
## [121] "RPS6KB1" "TFRC" "XRCC1" "RAB11A" "SQSTM1" "GAB2"
## [127] "WWTR1" "ANLN" "DIABLO" "NEK7" "RICTOR" "TP53BP1"
## [133] "FASN" "BRAF" "LCN2" "RAD50" "SYP" "COL6A1"
## [139] "CDH2" "TGM2" "DIRAS3" "GATA3" "RBM15" "TSC1"
## [145] "NF2" "TTF1" "XBP1"saveRDS(geneNames, file = "data/sel_features/gene_converted/genes_ggm.rds")2. Pathway Analysis
A. GO Classification
ggo_MF <- list()#functional profile of a geneset for Molecular Function
ggo_BP <- list()#functional profile of a geneset for Biological Process
ggo_CC <- list()#functional profile of a geneset for Cellular Component
for(z in 1:length(geneNames)){
print(z)
input <- geneNames[[z]]
ggo_MF[[z]] <- groupGO(gene=input,
OrgDb = org.Hs.eg.db,
ont="MF",
keyType="SYMBOL",
readable=TRUE)
ggo_BP[[z]] <- groupGO(gene=input,
OrgDb = org.Hs.eg.db,
ont="BP",
keyType="SYMBOL",
readable=TRUE)
ggo_CC[[z]] <- groupGO(gene=input,
OrgDb = org.Hs.eg.db,
ont="CC",
keyType="SYMBOL",
readable=TRUE)
}## [1] 1
## [1] 2
## [1] 3
## [1] 4
## [1] 5
## [1] 6
## [1] 7
## [1] 8
## [1] 9
## [1] 10
## [1] 11
## [1] 12
## [1] 13
## [1] 14
## [1] 15
## [1] 16
## [1] 17
## [1] 18
## [1] 19
## [1] 20
## [1] 21for(z in 1:length(geneNames)) {
print(head(ggo_MF[[z]]))
print(head(ggo_BP[[z]]))
print(head(ggo_CC[[z]]))
}## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/14
## GO:0003824 GO:0003824 catalytic activity 7 7/14
## GO:0005198 GO:0005198 structural molecule activity 1 1/14
## GO:0005215 GO:0005215 transporter activity 0 0/14
## GO:0005488 GO:0005488 binding 14 14/14
## GO:0009055 GO:0009055 electron transfer activity 0 0/14
## geneID
## GO:0003774 MYH11
## GO:0003824 GAPDH/FASN/ATM/G6PD/PTEN/MSH6/MSH2
## GO:0005198 MYH11
## GO:0005215
## GO:0005488 IGFBP2/PDCD4/GAPDH/FASN/MYH11/TFRC/GATA3/ATM/TTF1/G6PD/AR/PTEN/MSH6/MSH2
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 7 7/14
## GO:0002376 GO:0002376 immune system process 8 8/14
## GO:0008152 GO:0008152 metabolic process 12 12/14
## GO:0009987 GO:0009987 cellular process 14 14/14
## GO:0016032 GO:0016032 viral process 1 1/14
## GO:0022414 GO:0022414 reproductive process 7 7/14
## geneID
## GO:0000003 IGFBP2/GATA3/ATM/AR/PTEN/MSH6/MSH2
## GO:0002376 IGFBP2/GAPDH/TFRC/GATA3/ATM/G6PD/MSH6/MSH2
## GO:0008152 PDCD4/GAPDH/FASN/TFRC/GATA3/ATM/TTF1/G6PD/AR/PTEN/MSH6/MSH2
## GO:0009987 IGFBP2/PDCD4/GAPDH/FASN/MYH11/TFRC/GATA3/ATM/TTF1/G6PD/AR/PTEN/MSH6/MSH2
## GO:0016032 TFRC
## GO:0022414 IGFBP2/GATA3/ATM/AR/PTEN/MSH6/MSH2
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 8 8/14
## GO:0044423 GO:0044423 virion component 0 0/14
## GO:0110165 GO:0110165 cellular anatomical entity 14 14/14
## geneID
## GO:0032991 GAPDH/MYH11/TFRC/GATA3/ATM/AR/MSH6/MSH2
## GO:0044423
## GO:0110165 IGFBP2/PDCD4/GAPDH/FASN/MYH11/TFRC/GATA3/ATM/TTF1/G6PD/AR/PTEN/MSH6/MSH2
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/46
## GO:0003824 GO:0003824 catalytic activity 17 17/46
## GO:0005198 GO:0005198 structural molecule activity 5 5/46
## GO:0005215 GO:0005215 transporter activity 0 0/46
## GO:0005488 GO:0005488 binding 46 46/46
## GO:0009055 GO:0009055 electron transfer activity 0 0/46
## geneID
## GO:0003774 MYH9
## GO:0003824 GAPDH/EEF2/HSPA1A/TGM2/CCND1/FASN/PRKCA/PIK3R1/TUBA1B/G6PD/CDKN1A/ADAR/RAB11A/PARP1/KDR/CDK1/IDH3A
## GO:0005198 FN1/RPS6/TUBA1B/COL6A1/CTNNA1
## GO:0005215
## GO:0005488 GAPDH/SQSTM1/FN1/EEF2/HSPA1A/IGFBP2/RPS6/SYP/CTNNB1/TGM2/CDH2/CCND1/FASN/SERPINE1/PRKCA/PIK3R1/TUBA1B/COL6A1/G6PD/CDKN1A/PEA15/CTNNA1/PDCD4/NDRG1/ERBB3/ANXA1/ADAR/TFRC/YWHAZ/YWHAB/PXN/ERRFI1/EIF4G1/STMN1/PIK3R2/ITGA2/MYH9/YWHAE/RAB11A/PARP1/KDR/CDK1/BCL2L1/CCNB1/PREX1/IDH3A
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 11 11/46
## GO:0002376 GO:0002376 immune system process 22 22/46
## GO:0008152 GO:0008152 metabolic process 35 35/46
## GO:0009987 GO:0009987 cellular process 46 46/46
## GO:0016032 GO:0016032 viral process 5 5/46
## GO:0022414 GO:0022414 reproductive process 11 11/46
## geneID
## GO:0000003 IGFBP2/CTNNB1/COL6A1/CTNNA1/ERRFI1/ITGA2/MYH9/PARP1/KDR/CDK1/BCL2L1
## GO:0002376 GAPDH/SQSTM1/FN1/HSPA1A/IGFBP2/CTNNB1/SERPINE1/PRKCA/PIK3R1/G6PD/CDKN1A/NDRG1/ANXA1/ADAR/TFRC/YWHAZ/PIK3R2/ITGA2/MYH9/YWHAE/PARP1/PREX1
## GO:0008152 GAPDH/SQSTM1/FN1/EEF2/HSPA1A/RPS6/CTNNB1/TGM2/CCND1/FASN/SERPINE1/PRKCA/PIK3R1/COL6A1/G6PD/CDKN1A/PDCD4/ERBB3/ANXA1/ADAR/TFRC/YWHAZ/YWHAB/ERRFI1/EIF4G1/PIK3R2/ITGA2/MYH9/YWHAE/PARP1/KDR/CDK1/CCNB1/PREX1/IDH3A
## GO:0009987 GAPDH/SQSTM1/FN1/EEF2/HSPA1A/IGFBP2/RPS6/SYP/CTNNB1/TGM2/CDH2/CCND1/FASN/SERPINE1/PRKCA/PIK3R1/TUBA1B/COL6A1/G6PD/CDKN1A/PEA15/CTNNA1/PDCD4/NDRG1/ERBB3/ANXA1/ADAR/TFRC/YWHAZ/YWHAB/PXN/ERRFI1/EIF4G1/STMN1/PIK3R2/ITGA2/MYH9/YWHAE/RAB11A/PARP1/KDR/CDK1/BCL2L1/CCNB1/PREX1/IDH3A
## GO:0016032 HSPA1A/ADAR/TFRC/ITGA2/CDK1
## GO:0022414 IGFBP2/CTNNB1/COL6A1/CTNNA1/ERRFI1/ITGA2/MYH9/PARP1/KDR/CDK1/BCL2L1
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 31 31/46
## GO:0044423 GO:0044423 virion component 0 0/46
## GO:0110165 GO:0110165 cellular anatomical entity 46 46/46
## geneID
## GO:0032991 GAPDH/FN1/EEF2/HSPA1A/RPS6/CTNNB1/TGM2/CDH2/CCND1/SERPINE1/PRKCA/PIK3R1/COL6A1/CDKN1A/PEA15/CTNNA1/ERBB3/ADAR/TFRC/PXN/EIF4G1/PIK3R2/ITGA2/MYH9/RAB11A/PARP1/KDR/CDK1/BCL2L1/CCNB1/IDH3A
## GO:0044423
## GO:0110165 GAPDH/SQSTM1/FN1/EEF2/HSPA1A/IGFBP2/RPS6/SYP/CTNNB1/TGM2/CDH2/CCND1/FASN/SERPINE1/PRKCA/PIK3R1/TUBA1B/COL6A1/G6PD/CDKN1A/PEA15/CTNNA1/PDCD4/NDRG1/ERBB3/ANXA1/ADAR/TFRC/YWHAZ/YWHAB/PXN/ERRFI1/EIF4G1/STMN1/PIK3R2/ITGA2/MYH9/YWHAE/RAB11A/PARP1/KDR/CDK1/BCL2L1/CCNB1/PREX1/IDH3A
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/55
## GO:0003824 GO:0003824 catalytic activity 21 21/55
## GO:0005198 GO:0005198 structural molecule activity 5 5/55
## GO:0005215 GO:0005215 transporter activity 0 0/55
## GO:0005488 GO:0005488 binding 55 55/55
## GO:0009055 GO:0009055 electron transfer activity 0 0/55
## geneID
## GO:0003774 MYH9
## GO:0003824 GAPDH/HSPA1A/EEF2/TGM2/FASN/PIK3R1/G6PD/CDKN1A/PRKCA/CCND1/TUBA1B/ADAR/DIRAS3/AKT2/PRDX1/AKT1/CDK1/PARK7/KDR/RAB11A/PARP1
## GO:0005198 FN1/RPS6/COL6A1/TUBA1B/CTNNA1
## GO:0005215
## GO:0005488 GAPDH/SQSTM1/FN1/HSPA1A/EEF2/IGFBP2/SYP/RPS6/TGM2/CTNNB1/COL6A1/CDH2/FASN/SERPINE1/ERBB3/PIK3R1/G6PD/CDKN1A/PRKCA/CCND1/TUBA1B/PEA15/ANXA1/ADAR/PDCD4/NDRG1/CTNNA1/TFRC/ITGA2/ERRFI1/PIK3R2/PXN/YWHAZ/MYH9/DIRAS3/STMN1/EIF4G1/YWHAE/AKT2/CCNB1/YWHAB/PREX1/PRDX1/AKT1/CDK1/ANLN/SHC1/JUN/PARK7/BCL2L1/KDR/RAB11A/FOXM1/PARP1/ANXA7
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 14 14/55
## GO:0002376 GO:0002376 immune system process 25 25/55
## GO:0008152 GO:0008152 metabolic process 43 43/55
## GO:0009987 GO:0009987 cellular process 55 55/55
## GO:0016032 GO:0016032 viral process 7 7/55
## GO:0022414 GO:0022414 reproductive process 14 14/55
## geneID
## GO:0000003 IGFBP2/CTNNB1/COL6A1/CTNNA1/ITGA2/ERRFI1/MYH9/DIRAS3/AKT1/CDK1/PARK7/BCL2L1/KDR/PARP1
## GO:0002376 GAPDH/SQSTM1/FN1/HSPA1A/IGFBP2/CTNNB1/SERPINE1/PIK3R1/G6PD/CDKN1A/PRKCA/ANXA1/ADAR/NDRG1/TFRC/ITGA2/PIK3R2/YWHAZ/MYH9/YWHAE/PREX1/PRDX1/AKT1/PARK7/PARP1
## GO:0008152 GAPDH/SQSTM1/FN1/HSPA1A/EEF2/RPS6/TGM2/CTNNB1/COL6A1/FASN/SERPINE1/ERBB3/PIK3R1/G6PD/CDKN1A/PRKCA/CCND1/ANXA1/ADAR/PDCD4/TFRC/ITGA2/ERRFI1/PIK3R2/YWHAZ/MYH9/DIRAS3/EIF4G1/YWHAE/AKT2/CCNB1/YWHAB/PREX1/PRDX1/AKT1/CDK1/SHC1/JUN/PARK7/KDR/FOXM1/PARP1/ANXA7
## GO:0009987 GAPDH/SQSTM1/FN1/HSPA1A/EEF2/IGFBP2/SYP/RPS6/TGM2/CTNNB1/COL6A1/CDH2/FASN/SERPINE1/ERBB3/PIK3R1/G6PD/CDKN1A/PRKCA/CCND1/TUBA1B/PEA15/ANXA1/ADAR/PDCD4/NDRG1/CTNNA1/TFRC/ITGA2/ERRFI1/PIK3R2/PXN/YWHAZ/MYH9/DIRAS3/STMN1/EIF4G1/YWHAE/AKT2/CCNB1/YWHAB/PREX1/PRDX1/AKT1/CDK1/ANLN/SHC1/JUN/PARK7/BCL2L1/KDR/RAB11A/FOXM1/PARP1/ANXA7
## GO:0016032 HSPA1A/ADAR/TFRC/ITGA2/AKT1/CDK1/JUN
## GO:0022414 IGFBP2/CTNNB1/COL6A1/CTNNA1/ITGA2/ERRFI1/MYH9/DIRAS3/AKT1/CDK1/PARK7/BCL2L1/KDR/PARP1
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 35 35/55
## GO:0044423 GO:0044423 virion component 0 0/55
## GO:0110165 GO:0110165 cellular anatomical entity 55 55/55
## geneID
## GO:0032991 GAPDH/FN1/HSPA1A/EEF2/RPS6/TGM2/CTNNB1/COL6A1/CDH2/SERPINE1/ERBB3/PIK3R1/CDKN1A/PRKCA/CCND1/PEA15/ADAR/CTNNA1/TFRC/ITGA2/PIK3R2/PXN/MYH9/EIF4G1/CCNB1/AKT1/CDK1/SHC1/JUN/PARK7/BCL2L1/KDR/RAB11A/FOXM1/PARP1
## GO:0044423
## GO:0110165 GAPDH/SQSTM1/FN1/HSPA1A/EEF2/IGFBP2/SYP/RPS6/TGM2/CTNNB1/COL6A1/CDH2/FASN/SERPINE1/ERBB3/PIK3R1/G6PD/CDKN1A/PRKCA/CCND1/TUBA1B/PEA15/ANXA1/ADAR/PDCD4/NDRG1/CTNNA1/TFRC/ITGA2/ERRFI1/PIK3R2/PXN/YWHAZ/MYH9/DIRAS3/STMN1/EIF4G1/YWHAE/AKT2/CCNB1/YWHAB/PREX1/PRDX1/AKT1/CDK1/ANLN/SHC1/JUN/PARK7/BCL2L1/KDR/RAB11A/FOXM1/PARP1/ANXA7
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/113
## GO:0003824 GO:0003824 catalytic activity 55 55/113
## GO:0005198 GO:0005198 structural molecule activity 3 3/113
## GO:0005215 GO:0005215 transporter activity 2 2/113
## GO:0005488 GO:0005488 binding 113 113/113
## GO:0009055 GO:0009055 electron transfer activity 0 0/113
## geneID
## GO:0003774 MYH9
## GO:0003824 MET/BAP1/AKT2/PTEN/G6PD/KIT/NCOA3/KRAS/NRAS/PTK2/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/ATM/PARP1/XIAP/CASP8/CHEK1/GSK3B/IGF1R/PRKAA1/MAPK8/TUBA1B/CHEK2/PRKCD/RAB25/ACACA/HSPA1A/ADAR/AXL/MSH2/CASP3/CCNE1/ASNS/EEF2/GAPDH/MSH6/PRDX1/PIK3CA/PRKCA/MAPK1/RET/RPS6KB1/RAB11A/NEK7/ERCC1/INPP4B/FASN/BRAF/RAD50
## GO:0005198 TUBA1B/FN1/RPS6
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/KRAS/NRAS/RB1/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/CASP8/CHEK1/DVL3/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/MAPK8/PXN/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/BID/CHEK2/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/HSPA1A/ADAR/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ASNS/CTNNB1/EEF2/EIF4E/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/PIK3CA/PRKCA/MAPK1/RET/RPS6/RPS6KB1/TFRC/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/ERCC1/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 32 32/113
## GO:0002376 GO:0002376 immune system process 58 58/113
## GO:0008152 GO:0008152 metabolic process 99 99/113
## GO:0009987 GO:0009987 cellular process 113 113/113
## GO:0016032 GO:0016032 viral process 11 11/113
## GO:0022414 GO:0022414 reproductive process 31 31/113
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/CASP8/IGF1R/ITGA2/CCNE2/AXL/MSH2/CASP3/CCNE1/CTNNB1/MSH6/IGFBP2/PIK3CA/RPS6KB1/ERCC1/RAD50
## GO:0002376 ESR1/BAP1/G6PD/BCL2/KIT/RB1/MYH9/PTK2/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/IGF1R/ITGA2/MAPT/MAPK8/YWHAE/ARID1A/BID/PRKCD/HSPA1A/ADAR/AXL/CAV1/MSH2/CASP3/ANXA1/CTNNB1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/PIK3CA/PRKCA/MAPK1/RET/RPS6KB1/TFRC/SQSTM1/GAB2/NDRG1/NEK7/ERCC1/TP53BP1/BRAF/LCN2
## GO:0008152 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/KRAS/RB1/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/ATM/STAT5A/STAT3/PARP1/XIAP/CASP8/CHEK1/DVL3/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/MAPK8/SRSF1/YWHAE/ARID1A/CCNE2/BID/CHEK2/PRKCD/MACC1/ACACA/E2F1/HSPA1A/ADAR/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ASNS/CTNNB1/EEF2/EIF4E/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/PRDX1/PIK3CA/PRKCA/MAPK1/RET/RPS6/RPS6KB1/TFRC/SQSTM1/WWTR1/DIABLO/NEK7/RICTOR/ERCC1/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009987 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/KRAS/NRAS/RB1/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/CASP8/CHEK1/DVL3/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/MAPK8/PXN/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/BID/CHEK2/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/HSPA1A/ADAR/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ASNS/CTNNB1/EEF2/EIF4E/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/PIK3CA/PRKCA/MAPK1/RET/RPS6/RPS6KB1/TFRC/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/ERCC1/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0016032 BCL2/EGFR/JUN/AKT1/GSK3B/ITGA2/HSPA1A/ADAR/AXL/CAV1/TFRC
## GO:0022414 ESR1/ERRFI1/PTEN/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/CASP8/IGF1R/ITGA2/CCNE2/AXL/MSH2/CASP3/CCNE1/CTNNB1/MSH6/IGFBP2/PIK3CA/RPS6KB1/ERCC1/RAD50
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 73 73/113
## GO:0044423 GO:0044423 virion component 0 0/113
## GO:0110165 GO:0110165 cellular anatomical entity 113 113/113
## geneID
## GO:0032991 ESR1/MET/BAP1/BCL2/KIT/NCOA3/ERBB3/RB1/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/CASP8/CHEK1/DVL3/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PXN/SRSF1/ARID1A/PEA15/CCNE2/E2F1/HSPA1A/ADAR/AXL/CAV1/MSH2/CASP3/CCNE1/YAP1/CTNNB1/EEF2/EIF4E/EIF4G1/FOXM1/FN1/GAPDH/MSH6/PIK3CA/PRKCA/RET/RPS6/TFRC/RAB11A/WWTR1/DIABLO/RICTOR/ERCC1/TP53BP1/RAD50
## GO:0044423
## GO:0110165 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/KRAS/NRAS/RB1/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/CASP8/CHEK1/DVL3/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/MAPK8/PXN/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/BID/CHEK2/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/HSPA1A/ADAR/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ASNS/CTNNB1/EEF2/EIF4E/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/PIK3CA/PRKCA/MAPK1/RET/RPS6/RPS6KB1/TFRC/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/ERCC1/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/125
## GO:0003824 GO:0003824 catalytic activity 60 60/125
## GO:0005198 GO:0005198 structural molecule activity 4 4/125
## GO:0005215 GO:0005215 transporter activity 2 2/125
## GO:0005488 GO:0005488 binding 125 125/125
## GO:0009055 GO:0009055 electron transfer activity 0 0/125
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/KIT/NCOA3/HSPA1A/KRAS/NRAS/ADAR/PTK2/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/VHL/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/MTOR/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/TUBA1B/EEF2K/CHEK2/PRKCD/RAB25/ACACA/AXL/MSH2/CASP3/CCNE1/ASNS/EEF2/GAPDH/MSH6/PRDX1/PIK3CA/RET/RPS6KB1/XRCC1/RAB11A/NEK7/ERCC1/INPP4B/FASN/BRAF/RAD50
## GO:0005198 TUBA1B/MYH11/FN1/RPS6
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/CASP8/CDK1/CHEK1/CTNNB1/DVL3/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/EEF2K/AKT1S1/BID/CHEK2/MYH11/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ASNS/EEF2/EIF4E/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/PIK3CA/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/ERCC1/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 36 36/125
## GO:0002376 GO:0002376 immune system process 62 62/125
## GO:0008152 GO:0008152 metabolic process 110 110/125
## GO:0009987 GO:0009987 cellular process 125 125/125
## GO:0016032 GO:0016032 viral process 14 14/125
## GO:0022414 GO:0022414 reproductive process 35 35/125
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/CASP8/CDK1/CTNNB1/MTOR/IGF1R/ITGA2/CCNE2/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/ERCC1/RAD50
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/BCL2/KIT/HSPA1A/RB1/ADAR/MYH9/PTK2/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/MTOR/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/YWHAE/ARID1A/BECN1/BID/PRKCD/AXL/CAV1/MSH2/CASP3/ANXA1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/PIK3CA/RET/RPS6KB1/TFRC/SQSTM1/GAB2/NDRG1/NEK7/ERCC1/TP53BP1/BRAF/LCN2
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/HSPA1A/KRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/VHL/ATM/STAT5A/STAT3/PARP1/XIAP/CASP8/CDK1/CHEK1/CTNNB1/DVL3/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/SRSF1/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/AKT1S1/BID/CHEK2/YWHAB/PRKCD/MACC1/ACACA/E2F1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ASNS/EEF2/EIF4E/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/SMAD4/PRDX1/PIK3CA/RET/RPS6/RPS6KB1/TFRC/XRCC1/SQSTM1/WWTR1/DIABLO/NEK7/RICTOR/ERCC1/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/CASP8/CDK1/CHEK1/CTNNB1/DVL3/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/EEF2K/AKT1S1/BID/CHEK2/MYH11/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ASNS/EEF2/EIF4E/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/PIK3CA/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/ERCC1/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0016032 NOTCH1/BCL2/HSPA1A/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/BECN1/AXL/CAV1/TFRC
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/CASP8/CDK1/CTNNB1/MTOR/IGF1R/ITGA2/CCNE2/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/ERCC1/RAD50
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 82 82/125
## GO:0044423 GO:0044423 virion component 0 0/125
## GO:0110165 GO:0110165 cellular anatomical entity 125 125/125
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB3/HSPA1A/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/CASP8/CDK1/CHEK1/CTNNB1/DVL3/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/SRSF1/ARID1A/BECN1/PEA15/CCNE2/AKT1S1/MYH11/E2F1/AXL/CAV1/MSH2/CASP3/CCNE1/YAP1/EEF2/EIF4E/EIF4G1/FOXM1/FN1/GAPDH/MSH6/SMAD4/PIK3CA/RET/RPS6/TFRC/XRCC1/RAB11A/WWTR1/DIABLO/RICTOR/ERCC1/TP53BP1/RAD50
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/CASP8/CDK1/CHEK1/CTNNB1/DVL3/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/EEF2K/AKT1S1/BID/CHEK2/MYH11/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ASNS/EEF2/EIF4E/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/PIK3CA/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/ERCC1/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/140
## GO:0003824 GO:0003824 catalytic activity 63 63/140
## GO:0005198 GO:0005198 structural molecule activity 6 6/140
## GO:0005215 GO:0005215 transporter activity 2 2/140
## GO:0005488 GO:0005488 binding 140 140/140
## GO:0009055 GO:0009055 electron transfer activity 0 0/140
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/KIT/NCOA3/KRAS/NRAS/ADAR/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/EEF2/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/INPP4B/PRKCD/RAB25/ACACA/HSPA1A/AXL/PTK2/MSH2/CASP3/CCNE1/ASNS/GAPDH/MSH6/PRDX1/PIK3CA/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50/TGM2/DIRAS3/VHL/ACVRL1
## GO:0005198 TUBA1B/MYH11/FN1/RPS6/COL6A1/CTNNA1
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/CTNNA1/DIRAS3/GATA3/RBM15/TTF1/VHL/TSC1/ACVRL1
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 41 41/140
## GO:0002376 GO:0002376 immune system process 66 66/140
## GO:0008152 GO:0008152 metabolic process 122 122/140
## GO:0009987 GO:0009987 cellular process 140 140/140
## GO:0016032 GO:0016032 viral process 14 14/140
## GO:0022414 GO:0022414 reproductive process 40 40/140
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/CTNNA1/DIRAS3/GATA3
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/BCL2/KIT/RB1/ADAR/MYH9/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/TFRC/YWHAE/ARID1A/BECN1/NDRG1/BID/ERCC1/PRKCD/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/ANXA1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/SERPINE1/PIK3CA/RET/RPS6KB1/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2/GATA3/RBM15/TSC1
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/KRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/INPP4B/YWHAB/PRKCD/MACC1/ACACA/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/SQSTM1/WWTR1/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/TGM2/COL6A1/DIRAS3/GATA3/RBM15/TTF1/VHL/TSC1/ACVRL1
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/CTNNA1/DIRAS3/GATA3/RBM15/TTF1/VHL/TSC1/ACVRL1
## GO:0016032 NOTCH1/BCL2/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/TFRC/BECN1/HSPA1A/AXL/CAV1
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/CTNNA1/DIRAS3/GATA3
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 92 92/140
## GO:0044423 GO:0044423 virion component 0 0/140
## GO:0110165 GO:0110165 cellular anatomical entity 140 140/140
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB3/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/TFRC/ARID1A/BECN1/PEA15/CCNE2/DIABLO/AKT1S1/ERCC1/MYH11/E2F1/HSPA1A/AXL/CAV1/MSH2/CASP3/CCNE1/YAP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/SERPINE1/PIK3CA/RET/RPS6/XRCC1/RAB11A/WWTR1/RICTOR/TP53BP1/RAD50/TGM2/COL6A1/CDH2/CTNNA1/GATA3/RBM15/TSC1/ACVRL1
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/CTNNA1/DIRAS3/GATA3/RBM15/TTF1/VHL/TSC1/ACVRL1
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/144
## GO:0003824 GO:0003824 catalytic activity 65 65/144
## GO:0005198 GO:0005198 structural molecule activity 6 6/144
## GO:0005215 GO:0005215 transporter activity 2 2/144
## GO:0005488 GO:0005488 binding 144 144/144
## GO:0009055 GO:0009055 electron transfer activity 0 0/144
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/KIT/NCOA3/ERBB2/HSPA1A/KRAS/NRAS/ADAR/PTK2/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/VHL/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/EEF2/MTOR/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/INPP4B/PRKCD/RAB25/ACACA/AXL/MSH2/CASP3/CCNE1/ASNS/GAPDH/MSH6/PRDX1/PIK3CA/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50/TGM2/DIRAS3/ACVRL1
## GO:0005198 TUBA1B/MYH11/FN1/RPS6/COL6A1/CTNNA1
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/PREX1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/CTNNA1/DIRAS3/GATA3/RBM15/TTF1/TSC1/ACVRL1/XBP1
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 43 43/144
## GO:0002376 GO:0002376 immune system process 69 69/144
## GO:0008152 GO:0008152 metabolic process 126 126/144
## GO:0009987 GO:0009987 cellular process 144 144/144
## GO:0016032 GO:0016032 viral process 14 14/144
## GO:0022414 GO:0022414 reproductive process 42 42/144
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/AR/CASP8/CDK1/CTNNB1/MTOR/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/CTNNA1/DIRAS3/GATA3
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/BCL2/KIT/ERBB2/HSPA1A/RB1/ADAR/MYH9/PTK2/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/MTOR/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/TFRC/YWHAE/ARID1A/BECN1/NDRG1/BID/ERCC1/PRKCD/PREX1/AXL/CAV1/MSH2/CASP3/ANXA1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/SERPINE1/PIK3CA/RET/RPS6KB1/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2/GATA3/RBM15/TSC1/XBP1
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/HSPA1A/KRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/VHL/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/INPP4B/YWHAB/PRKCD/MACC1/ACACA/SMAD1/E2F1/PREX1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/SQSTM1/WWTR1/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/TGM2/COL6A1/DIRAS3/GATA3/RBM15/TTF1/TSC1/ACVRL1/XBP1
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/PREX1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/CTNNA1/DIRAS3/GATA3/RBM15/TTF1/TSC1/ACVRL1/XBP1
## GO:0016032 NOTCH1/BCL2/HSPA1A/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/TFRC/BECN1/AXL/CAV1
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/AR/CASP8/CDK1/CTNNB1/MTOR/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/CTNNA1/DIRAS3/GATA3
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 96 96/144
## GO:0044423 GO:0044423 virion component 0 0/144
## GO:0110165 GO:0110165 cellular anatomical entity 144 144/144
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB2/ERBB3/HSPA1A/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/TFRC/ARID1A/BECN1/PEA15/CCNE2/DIABLO/AKT1S1/ERCC1/MYH11/SMAD1/E2F1/AXL/CAV1/MSH2/CASP3/CCNE1/YAP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/SERPINE1/PIK3CA/RET/RPS6/XRCC1/RAB11A/WWTR1/RICTOR/TP53BP1/RAD50/TGM2/COL6A1/CDH2/CTNNA1/GATA3/RBM15/TSC1/ACVRL1/XBP1
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/PREX1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/CTNNA1/DIRAS3/GATA3/RBM15/TTF1/TSC1/ACVRL1/XBP1
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/18
## GO:0003824 GO:0003824 catalytic activity 7 7/18
## GO:0005198 GO:0005198 structural molecule activity 1 1/18
## GO:0005215 GO:0005215 transporter activity 0 0/18
## GO:0005488 GO:0005488 binding 18 18/18
## GO:0009055 GO:0009055 electron transfer activity 0 0/18
## geneID
## GO:0003774 MYH11
## GO:0003824 GAPDH/G6PD/FASN/ATM/MSH6/EGFR/MSH2
## GO:0005198 MYH11
## GO:0005215
## GO:0005488 GAPDH/G6PD/IGFBP2/FASN/PDCD4/AR/MYH11/PREX1/ATM/TTF1/MSH6/TFRC/RBM15/GATA3/EGFR/TSC1/IRS1/MSH2
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 7 7/18
## GO:0002376 GO:0002376 immune system process 11 11/18
## GO:0008152 GO:0008152 metabolic process 16 16/18
## GO:0009987 GO:0009987 cellular process 18 18/18
## GO:0016032 GO:0016032 viral process 2 2/18
## GO:0022414 GO:0022414 reproductive process 7 7/18
## geneID
## GO:0000003 IGFBP2/AR/ATM/MSH6/GATA3/EGFR/MSH2
## GO:0002376 GAPDH/G6PD/IGFBP2/PREX1/ATM/MSH6/TFRC/RBM15/GATA3/TSC1/MSH2
## GO:0008152 GAPDH/G6PD/FASN/PDCD4/AR/PREX1/ATM/TTF1/MSH6/TFRC/RBM15/GATA3/EGFR/TSC1/IRS1/MSH2
## GO:0009987 GAPDH/G6PD/IGFBP2/FASN/PDCD4/AR/MYH11/PREX1/ATM/TTF1/MSH6/TFRC/RBM15/GATA3/EGFR/TSC1/IRS1/MSH2
## GO:0016032 TFRC/EGFR
## GO:0022414 IGFBP2/AR/ATM/MSH6/GATA3/EGFR/MSH2
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 12 12/18
## GO:0044423 GO:0044423 virion component 0 0/18
## GO:0110165 GO:0110165 cellular anatomical entity 18 18/18
## geneID
## GO:0032991 GAPDH/AR/MYH11/ATM/MSH6/TFRC/RBM15/GATA3/EGFR/TSC1/IRS1/MSH2
## GO:0044423
## GO:0110165 GAPDH/G6PD/IGFBP2/FASN/PDCD4/AR/MYH11/PREX1/ATM/TTF1/MSH6/TFRC/RBM15/GATA3/EGFR/TSC1/IRS1/MSH2
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/25
## GO:0003824 GO:0003824 catalytic activity 13 13/25
## GO:0005198 GO:0005198 structural molecule activity 1 1/25
## GO:0005215 GO:0005215 transporter activity 0 0/25
## GO:0005488 GO:0005488 binding 25 25/25
## GO:0009055 GO:0009055 electron transfer activity 0 0/25
## geneID
## GO:0003774 MYH11
## GO:0003824 FASN/GAPDH/G6PD/MSH6/ATM/ASNS/PTEN/MSH2/EGFR/INPP4B/VHL/PRDX1/PDK1
## GO:0005198 MYH11
## GO:0005215
## GO:0005488 TFRC/FASN/GATA3/GAPDH/G6PD/MYH11/PDCD4/MSH6/ATM/RBM15/ASNS/PTEN/MSH2/IGFBP2/PEA15/EGFR/INPP4B/TSC1/VHL/TTF1/IRS1/PRDX1/XBP1/NF2/PDK1
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 7 7/25
## GO:0002376 GO:0002376 immune system process 12 12/25
## GO:0008152 GO:0008152 metabolic process 22 22/25
## GO:0009987 GO:0009987 cellular process 25 25/25
## GO:0016032 GO:0016032 viral process 2 2/25
## GO:0022414 GO:0022414 reproductive process 7 7/25
## geneID
## GO:0000003 GATA3/MSH6/ATM/PTEN/MSH2/IGFBP2/EGFR
## GO:0002376 TFRC/GATA3/GAPDH/G6PD/MSH6/ATM/RBM15/MSH2/IGFBP2/TSC1/PRDX1/XBP1
## GO:0008152 TFRC/FASN/GATA3/GAPDH/G6PD/PDCD4/MSH6/ATM/RBM15/ASNS/PTEN/MSH2/EGFR/INPP4B/TSC1/VHL/TTF1/IRS1/PRDX1/XBP1/NF2/PDK1
## GO:0009987 TFRC/FASN/GATA3/GAPDH/G6PD/MYH11/PDCD4/MSH6/ATM/RBM15/ASNS/PTEN/MSH2/IGFBP2/PEA15/EGFR/INPP4B/TSC1/VHL/TTF1/IRS1/PRDX1/XBP1/NF2/PDK1
## GO:0016032 TFRC/EGFR
## GO:0022414 GATA3/MSH6/ATM/PTEN/MSH2/IGFBP2/EGFR
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 14 14/25
## GO:0044423 GO:0044423 virion component 0 0/25
## GO:0110165 GO:0110165 cellular anatomical entity 25 25/25
## geneID
## GO:0032991 TFRC/GATA3/GAPDH/MYH11/MSH6/ATM/RBM15/MSH2/PEA15/EGFR/TSC1/IRS1/XBP1/PDK1
## GO:0044423
## GO:0110165 TFRC/FASN/GATA3/GAPDH/G6PD/MYH11/PDCD4/MSH6/ATM/RBM15/ASNS/PTEN/MSH2/IGFBP2/PEA15/EGFR/INPP4B/TSC1/VHL/TTF1/IRS1/PRDX1/XBP1/NF2/PDK1
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/48
## GO:0003824 GO:0003824 catalytic activity 18 18/48
## GO:0005198 GO:0005198 structural molecule activity 5 5/48
## GO:0005215 GO:0005215 transporter activity 0 0/48
## GO:0005488 GO:0005488 binding 48 48/48
## GO:0009055 GO:0009055 electron transfer activity 0 0/48
## geneID
## GO:0003774 MYH9
## GO:0003824 GAPDH/EEF2/TGM2/HSPA1A/FASN/PRKCA/G6PD/PIK3R1/CCND1/AKT2/CDKN1A/AKT1/ADAR/RAB11A/PARP1/DIRAS3/KDR/TUBA1B
## GO:0005198 COL6A1/RPS6/CTNNA1/FN1/TUBA1B
## GO:0005215
## GO:0005488 GAPDH/SQSTM1/EEF2/TGM2/HSPA1A/IGFBP2/COL6A1/SYP/CTNNB1/CDH2/FASN/RPS6/PRKCA/ANXA1/G6PD/NDRG1/ERBB3/CTNNA1/SERPINE1/PDCD4/FN1/PIK3R1/CCND1/MYH9/PXN/ERRFI1/PREX1/AKT2/CDKN1A/YWHAZ/PEA15/RBM3/AKT1/ITGA2/ADAR/RAB11A/YWHAB/TFRC/PARP1/DIRAS3/KDR/EIF4G1/JUN/TUBA1B/STAT5A/PIK3R2/XBP1/NOTCH3
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 11 11/48
## GO:0002376 GO:0002376 immune system process 23 23/48
## GO:0008152 GO:0008152 metabolic process 39 39/48
## GO:0009987 GO:0009987 cellular process 48 48/48
## GO:0016032 GO:0016032 viral process 6 6/48
## GO:0022414 GO:0022414 reproductive process 11 11/48
## geneID
## GO:0000003 IGFBP2/COL6A1/CTNNB1/CTNNA1/MYH9/ERRFI1/AKT1/ITGA2/PARP1/DIRAS3/KDR
## GO:0002376 GAPDH/SQSTM1/HSPA1A/IGFBP2/CTNNB1/PRKCA/ANXA1/G6PD/NDRG1/SERPINE1/FN1/PIK3R1/MYH9/PREX1/CDKN1A/YWHAZ/AKT1/ITGA2/ADAR/TFRC/PARP1/PIK3R2/XBP1
## GO:0008152 GAPDH/SQSTM1/EEF2/TGM2/HSPA1A/COL6A1/CTNNB1/FASN/RPS6/PRKCA/ANXA1/G6PD/ERBB3/SERPINE1/PDCD4/FN1/PIK3R1/CCND1/MYH9/ERRFI1/PREX1/AKT2/CDKN1A/YWHAZ/RBM3/AKT1/ITGA2/ADAR/YWHAB/TFRC/PARP1/DIRAS3/KDR/EIF4G1/JUN/STAT5A/PIK3R2/XBP1/NOTCH3
## GO:0009987 GAPDH/SQSTM1/EEF2/TGM2/HSPA1A/IGFBP2/COL6A1/SYP/CTNNB1/CDH2/FASN/RPS6/PRKCA/ANXA1/G6PD/NDRG1/ERBB3/CTNNA1/SERPINE1/PDCD4/FN1/PIK3R1/CCND1/MYH9/PXN/ERRFI1/PREX1/AKT2/CDKN1A/YWHAZ/PEA15/RBM3/AKT1/ITGA2/ADAR/RAB11A/YWHAB/TFRC/PARP1/DIRAS3/KDR/EIF4G1/JUN/TUBA1B/STAT5A/PIK3R2/XBP1/NOTCH3
## GO:0016032 HSPA1A/AKT1/ITGA2/ADAR/TFRC/JUN
## GO:0022414 IGFBP2/COL6A1/CTNNB1/CTNNA1/MYH9/ERRFI1/AKT1/ITGA2/PARP1/DIRAS3/KDR
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 33 33/48
## GO:0044423 GO:0044423 virion component 0 0/48
## GO:0110165 GO:0110165 cellular anatomical entity 48 48/48
## geneID
## GO:0032991 GAPDH/EEF2/TGM2/HSPA1A/COL6A1/CTNNB1/CDH2/RPS6/PRKCA/ERBB3/CTNNA1/SERPINE1/FN1/PIK3R1/CCND1/MYH9/PXN/CDKN1A/PEA15/RBM3/AKT1/ITGA2/ADAR/RAB11A/TFRC/PARP1/KDR/EIF4G1/JUN/STAT5A/PIK3R2/XBP1/NOTCH3
## GO:0044423
## GO:0110165 GAPDH/SQSTM1/EEF2/TGM2/HSPA1A/IGFBP2/COL6A1/SYP/CTNNB1/CDH2/FASN/RPS6/PRKCA/ANXA1/G6PD/NDRG1/ERBB3/CTNNA1/SERPINE1/PDCD4/FN1/PIK3R1/CCND1/MYH9/PXN/ERRFI1/PREX1/AKT2/CDKN1A/YWHAZ/PEA15/RBM3/AKT1/ITGA2/ADAR/RAB11A/YWHAB/TFRC/PARP1/DIRAS3/KDR/EIF4G1/JUN/TUBA1B/STAT5A/PIK3R2/XBP1/NOTCH3
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/45
## GO:0003824 GO:0003824 catalytic activity 18 18/45
## GO:0005198 GO:0005198 structural molecule activity 4 4/45
## GO:0005215 GO:0005215 transporter activity 0 0/45
## GO:0005488 GO:0005488 binding 45 45/45
## GO:0009055 GO:0009055 electron transfer activity 0 0/45
## geneID
## GO:0003774 MYH9
## GO:0003824 EEF2/GAPDH/HSPA1A/CCND1/ADAR/TUBA1B/FASN/CDKN1A/AKT1/TGM2/PRKCA/PIK3R1/DIRAS3/G6PD/PARK7/PRKCD/BAP1/IDH3A
## GO:0005198 FN1/RPS6/TUBA1B/COL6A1
## GO:0005215
## GO:0005488 FN1/SYP/EEF2/GAPDH/HSPA1A/CTNNB1/SQSTM1/RPS6/CCND1/ADAR/CDH2/TUBA1B/TFRC/SERPINE1/FASN/CDKN1A/PEA15/COL6A1/PIK3R2/SHC1/ITGA2/STMN1/NDRG1/AKT1/IGFBP2/YWHAE/TGM2/PXN/EIF4G1/PRKCA/PIK3R1/DIRAS3/G6PD/PARK7/MYH9/ANXA1/PRKCD/BAP1/PDCD4/JUN/CCNB1/DVL3/FOXM1/ANXA7/IDH3A
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 8 8/45
## GO:0002376 GO:0002376 immune system process 23 23/45
## GO:0008152 GO:0008152 metabolic process 37 37/45
## GO:0009987 GO:0009987 cellular process 45 45/45
## GO:0016032 GO:0016032 viral process 6 6/45
## GO:0022414 GO:0022414 reproductive process 8 8/45
## geneID
## GO:0000003 CTNNB1/COL6A1/ITGA2/AKT1/IGFBP2/DIRAS3/PARK7/MYH9
## GO:0002376 FN1/GAPDH/HSPA1A/CTNNB1/SQSTM1/ADAR/TFRC/SERPINE1/CDKN1A/PIK3R2/ITGA2/NDRG1/AKT1/IGFBP2/YWHAE/PRKCA/PIK3R1/G6PD/PARK7/MYH9/ANXA1/PRKCD/BAP1
## GO:0008152 FN1/EEF2/GAPDH/HSPA1A/CTNNB1/SQSTM1/RPS6/CCND1/ADAR/TFRC/SERPINE1/FASN/CDKN1A/COL6A1/PIK3R2/SHC1/ITGA2/AKT1/YWHAE/TGM2/EIF4G1/PRKCA/PIK3R1/DIRAS3/G6PD/PARK7/MYH9/ANXA1/PRKCD/BAP1/PDCD4/JUN/CCNB1/DVL3/FOXM1/ANXA7/IDH3A
## GO:0009987 FN1/SYP/EEF2/GAPDH/HSPA1A/CTNNB1/SQSTM1/RPS6/CCND1/ADAR/CDH2/TUBA1B/TFRC/SERPINE1/FASN/CDKN1A/PEA15/COL6A1/PIK3R2/SHC1/ITGA2/STMN1/NDRG1/AKT1/IGFBP2/YWHAE/TGM2/PXN/EIF4G1/PRKCA/PIK3R1/DIRAS3/G6PD/PARK7/MYH9/ANXA1/PRKCD/BAP1/PDCD4/JUN/CCNB1/DVL3/FOXM1/ANXA7/IDH3A
## GO:0016032 HSPA1A/ADAR/TFRC/ITGA2/AKT1/JUN
## GO:0022414 CTNNB1/COL6A1/ITGA2/AKT1/IGFBP2/DIRAS3/PARK7/MYH9
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 31 31/45
## GO:0044423 GO:0044423 virion component 0 0/45
## GO:0110165 GO:0110165 cellular anatomical entity 45 45/45
## geneID
## GO:0032991 FN1/EEF2/GAPDH/HSPA1A/CTNNB1/RPS6/CCND1/ADAR/CDH2/TFRC/SERPINE1/CDKN1A/PEA15/COL6A1/PIK3R2/SHC1/ITGA2/AKT1/TGM2/PXN/EIF4G1/PRKCA/PIK3R1/PARK7/MYH9/BAP1/JUN/CCNB1/DVL3/FOXM1/IDH3A
## GO:0044423
## GO:0110165 FN1/SYP/EEF2/GAPDH/HSPA1A/CTNNB1/SQSTM1/RPS6/CCND1/ADAR/CDH2/TUBA1B/TFRC/SERPINE1/FASN/CDKN1A/PEA15/COL6A1/PIK3R2/SHC1/ITGA2/STMN1/NDRG1/AKT1/IGFBP2/YWHAE/TGM2/PXN/EIF4G1/PRKCA/PIK3R1/DIRAS3/G6PD/PARK7/MYH9/ANXA1/PRKCD/BAP1/PDCD4/JUN/CCNB1/DVL3/FOXM1/ANXA7/IDH3A
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/53
## GO:0003824 GO:0003824 catalytic activity 19 19/53
## GO:0005198 GO:0005198 structural molecule activity 5 5/53
## GO:0005215 GO:0005215 transporter activity 0 0/53
## GO:0005488 GO:0005488 binding 53 53/53
## GO:0009055 GO:0009055 electron transfer activity 0 0/53
## geneID
## GO:0003774 MYH9
## GO:0003824 GAPDH/TGM2/HSPA1A/EEF2/PRKCA/FASN/G6PD/PIK3R1/CCND1/PARP1/AKT2/CDKN1A/KDR/AKT1/TUBA1B/RAB11A/DIRAS3/MET/ADAR
## GO:0005198 COL6A1/RPS6/FN1/CTNNA1/TUBA1B
## GO:0005215
## GO:0005488 GAPDH/SQSTM1/IGFBP2/TGM2/HSPA1A/EEF2/COL6A1/ERBB3/SYP/CDH2/PRKCA/FASN/CTNNB1/ANXA1/RPS6/PDCD4/G6PD/NDRG1/FN1/PIK3R1/CTNNA1/ERRFI1/SERPINE1/CCND1/MYH9/YWHAZ/PEA15/PXN/TFRC/PARP1/PREX1/AKT2/CDKN1A/EIF4G1/BCL2L1/KDR/AKT1/JUN/TUBA1B/PIK3R2/ITGA2/YWHAE/RAB11A/ETS1/STAT5A/DIRAS3/MET/ADAR/RBM3/STMN1/NOTCH3/YWHAB/ANXA7
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 12 12/53
## GO:0002376 GO:0002376 immune system process 24 24/53
## GO:0008152 GO:0008152 metabolic process 42 42/53
## GO:0009987 GO:0009987 cellular process 53 53/53
## GO:0016032 GO:0016032 viral process 6 6/53
## GO:0022414 GO:0022414 reproductive process 12 12/53
## geneID
## GO:0000003 IGFBP2/COL6A1/CTNNB1/CTNNA1/ERRFI1/MYH9/PARP1/BCL2L1/KDR/AKT1/ITGA2/DIRAS3
## GO:0002376 GAPDH/SQSTM1/IGFBP2/HSPA1A/PRKCA/CTNNB1/ANXA1/G6PD/NDRG1/FN1/PIK3R1/SERPINE1/MYH9/YWHAZ/TFRC/PARP1/PREX1/CDKN1A/AKT1/PIK3R2/ITGA2/YWHAE/ETS1/ADAR
## GO:0008152 GAPDH/SQSTM1/TGM2/HSPA1A/EEF2/COL6A1/ERBB3/PRKCA/FASN/CTNNB1/ANXA1/RPS6/PDCD4/G6PD/FN1/PIK3R1/ERRFI1/SERPINE1/CCND1/MYH9/YWHAZ/TFRC/PARP1/PREX1/AKT2/CDKN1A/EIF4G1/KDR/AKT1/JUN/PIK3R2/ITGA2/YWHAE/ETS1/STAT5A/DIRAS3/MET/ADAR/RBM3/NOTCH3/YWHAB/ANXA7
## GO:0009987 GAPDH/SQSTM1/IGFBP2/TGM2/HSPA1A/EEF2/COL6A1/ERBB3/SYP/CDH2/PRKCA/FASN/CTNNB1/ANXA1/RPS6/PDCD4/G6PD/NDRG1/FN1/PIK3R1/CTNNA1/ERRFI1/SERPINE1/CCND1/MYH9/YWHAZ/PEA15/PXN/TFRC/PARP1/PREX1/AKT2/CDKN1A/EIF4G1/BCL2L1/KDR/AKT1/JUN/TUBA1B/PIK3R2/ITGA2/YWHAE/RAB11A/ETS1/STAT5A/DIRAS3/MET/ADAR/RBM3/STMN1/NOTCH3/YWHAB/ANXA7
## GO:0016032 HSPA1A/TFRC/AKT1/JUN/ITGA2/ADAR
## GO:0022414 IGFBP2/COL6A1/CTNNB1/CTNNA1/ERRFI1/MYH9/PARP1/BCL2L1/KDR/AKT1/ITGA2/DIRAS3
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 35 35/53
## GO:0044423 GO:0044423 virion component 0 0/53
## GO:0110165 GO:0110165 cellular anatomical entity 53 53/53
## geneID
## GO:0032991 GAPDH/TGM2/HSPA1A/EEF2/COL6A1/ERBB3/CDH2/PRKCA/CTNNB1/RPS6/FN1/PIK3R1/CTNNA1/SERPINE1/CCND1/MYH9/PEA15/PXN/TFRC/PARP1/CDKN1A/EIF4G1/BCL2L1/KDR/AKT1/JUN/PIK3R2/ITGA2/RAB11A/ETS1/STAT5A/MET/ADAR/RBM3/NOTCH3
## GO:0044423
## GO:0110165 GAPDH/SQSTM1/IGFBP2/TGM2/HSPA1A/EEF2/COL6A1/ERBB3/SYP/CDH2/PRKCA/FASN/CTNNB1/ANXA1/RPS6/PDCD4/G6PD/NDRG1/FN1/PIK3R1/CTNNA1/ERRFI1/SERPINE1/CCND1/MYH9/YWHAZ/PEA15/PXN/TFRC/PARP1/PREX1/AKT2/CDKN1A/EIF4G1/BCL2L1/KDR/AKT1/JUN/TUBA1B/PIK3R2/ITGA2/YWHAE/RAB11A/ETS1/STAT5A/DIRAS3/MET/ADAR/RBM3/STMN1/NOTCH3/YWHAB/ANXA7
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 1 1/49
## GO:0003824 GO:0003824 catalytic activity 21 21/49
## GO:0005198 GO:0005198 structural molecule activity 5 5/49
## GO:0005215 GO:0005215 transporter activity 0 0/49
## GO:0005488 GO:0005488 binding 49 49/49
## GO:0009055 GO:0009055 electron transfer activity 0 0/49
## geneID
## GO:0003774 MYH9
## GO:0003824 GAPDH/HSPA1A/EEF2/ADAR/CCND1/TUBA1B/CDKN1A/FASN/PRKCA/TGM2/AKT1/DIRAS3/PCNA/G6PD/IDH3A/PRKCD/MAPK1/BAP1/PARK7/PIK3R1/CDK1
## GO:0005198 FN1/RPS6/TUBA1B/COL6A1/CTNNA1
## GO:0005215
## GO:0005488 FN1/GAPDH/SYP/SQSTM1/HSPA1A/EEF2/CTNNB1/RPS6/ADAR/CCND1/TUBA1B/CDH2/TFRC/CDKN1A/FASN/SERPINE1/COL6A1/PEA15/SHC1/PIK3R2/IGFBP2/ITGA2/YWHAE/STMN1/EIF4G1/NDRG1/PRKCA/TGM2/PXN/AKT1/DIRAS3/JUN/ANXA1/PCNA/PDCD4/MYH9/G6PD/IDH3A/PRKCD/MAPK1/BAP1/PARK7/PIK3R1/RBM3/ANLN/CCNB1/CDK1/CTNNA1/ANXA7
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 11 11/49
## GO:0002376 GO:0002376 immune system process 24 24/49
## GO:0008152 GO:0008152 metabolic process 39 39/49
## GO:0009987 GO:0009987 cellular process 49 49/49
## GO:0016032 GO:0016032 viral process 7 7/49
## GO:0022414 GO:0022414 reproductive process 11 11/49
## geneID
## GO:0000003 CTNNB1/COL6A1/IGFBP2/ITGA2/AKT1/DIRAS3/PCNA/MYH9/PARK7/CDK1/CTNNA1
## GO:0002376 FN1/GAPDH/SQSTM1/HSPA1A/CTNNB1/ADAR/TFRC/CDKN1A/SERPINE1/PIK3R2/IGFBP2/ITGA2/YWHAE/NDRG1/PRKCA/AKT1/ANXA1/MYH9/G6PD/PRKCD/MAPK1/BAP1/PARK7/PIK3R1
## GO:0008152 FN1/GAPDH/SQSTM1/HSPA1A/EEF2/CTNNB1/RPS6/ADAR/CCND1/TFRC/CDKN1A/FASN/SERPINE1/COL6A1/SHC1/PIK3R2/ITGA2/YWHAE/EIF4G1/PRKCA/TGM2/AKT1/DIRAS3/JUN/ANXA1/PCNA/PDCD4/MYH9/G6PD/IDH3A/PRKCD/MAPK1/BAP1/PARK7/PIK3R1/RBM3/CCNB1/CDK1/ANXA7
## GO:0009987 FN1/GAPDH/SYP/SQSTM1/HSPA1A/EEF2/CTNNB1/RPS6/ADAR/CCND1/TUBA1B/CDH2/TFRC/CDKN1A/FASN/SERPINE1/COL6A1/PEA15/SHC1/PIK3R2/IGFBP2/ITGA2/YWHAE/STMN1/EIF4G1/NDRG1/PRKCA/TGM2/PXN/AKT1/DIRAS3/JUN/ANXA1/PCNA/PDCD4/MYH9/G6PD/IDH3A/PRKCD/MAPK1/BAP1/PARK7/PIK3R1/RBM3/ANLN/CCNB1/CDK1/CTNNA1/ANXA7
## GO:0016032 HSPA1A/ADAR/TFRC/ITGA2/AKT1/JUN/CDK1
## GO:0022414 CTNNB1/COL6A1/IGFBP2/ITGA2/AKT1/DIRAS3/PCNA/MYH9/PARK7/CDK1/CTNNA1
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 33 33/49
## GO:0044423 GO:0044423 virion component 0 0/49
## GO:0110165 GO:0110165 cellular anatomical entity 49 49/49
## geneID
## GO:0032991 FN1/GAPDH/HSPA1A/EEF2/CTNNB1/RPS6/ADAR/CCND1/CDH2/TFRC/CDKN1A/SERPINE1/COL6A1/PEA15/SHC1/PIK3R2/ITGA2/EIF4G1/PRKCA/TGM2/PXN/AKT1/JUN/PCNA/MYH9/IDH3A/BAP1/PARK7/PIK3R1/RBM3/CCNB1/CDK1/CTNNA1
## GO:0044423
## GO:0110165 FN1/GAPDH/SYP/SQSTM1/HSPA1A/EEF2/CTNNB1/RPS6/ADAR/CCND1/TUBA1B/CDH2/TFRC/CDKN1A/FASN/SERPINE1/COL6A1/PEA15/SHC1/PIK3R2/IGFBP2/ITGA2/YWHAE/STMN1/EIF4G1/NDRG1/PRKCA/TGM2/PXN/AKT1/DIRAS3/JUN/ANXA1/PCNA/PDCD4/MYH9/G6PD/IDH3A/PRKCD/MAPK1/BAP1/PARK7/PIK3R1/RBM3/ANLN/CCNB1/CDK1/CTNNA1/ANXA7
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/130
## GO:0003824 GO:0003824 catalytic activity 60 60/130
## GO:0005198 GO:0005198 structural molecule activity 4 4/130
## GO:0005215 GO:0005215 transporter activity 2 2/130
## GO:0005488 GO:0005488 binding 130 130/130
## GO:0009055 GO:0009055 electron transfer activity 0 0/130
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/KIT/NCOA3/ERBB2/KRAS/NRAS/ADAR/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/EEF2/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/INPP4B/PRKCD/RAB25/ACACA/HSPA1A/AXL/PTK2/MSH2/CASP3/CCNE1/ASNS/GAPDH/MSH6/PRDX1/PIK3CA/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50
## GO:0005198 TUBA1B/MYH11/FN1/RPS6
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 38 38/130
## GO:0002376 GO:0002376 immune system process 64 64/130
## GO:0008152 GO:0008152 metabolic process 115 115/130
## GO:0009987 GO:0009987 cellular process 130 130/130
## GO:0016032 GO:0016032 viral process 14 14/130
## GO:0022414 GO:0022414 reproductive process 37 37/130
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/BCL2/KIT/ERBB2/RB1/ADAR/MYH9/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/TFRC/YWHAE/ARID1A/BECN1/NDRG1/BID/ERCC1/PRKCD/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/ANXA1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/SERPINE1/PIK3CA/RET/RPS6KB1/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/INPP4B/YWHAB/PRKCD/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/SQSTM1/WWTR1/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0016032 NOTCH1/BCL2/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/TFRC/BECN1/HSPA1A/AXL/CAV1
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 86 86/130
## GO:0044423 GO:0044423 virion component 0 0/130
## GO:0110165 GO:0110165 cellular anatomical entity 130 130/130
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB2/ERBB3/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/TFRC/ARID1A/BECN1/PEA15/CCNE2/DIABLO/AKT1S1/ERCC1/MYH11/SMAD1/E2F1/HSPA1A/AXL/CAV1/MSH2/CASP3/CCNE1/YAP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/SERPINE1/PIK3CA/RET/RPS6/XRCC1/RAB11A/WWTR1/RICTOR/TP53BP1/RAD50
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/125
## GO:0003824 GO:0003824 catalytic activity 59 59/125
## GO:0005198 GO:0005198 structural molecule activity 4 4/125
## GO:0005215 GO:0005215 transporter activity 2 2/125
## GO:0005488 GO:0005488 binding 125 125/125
## GO:0009055 GO:0009055 electron transfer activity 0 0/125
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 MET/BAP1/AKT2/PTEN/G6PD/KIT/NCOA3/KRAS/NRAS/ADAR/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/PARP1/XIAP/CHEK1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/INPP4B/PRKCD/RAB25/ACACA/HSPA1A/CASP9/AXL/PTK2/MSH2/CASP3/CCNE1/MAPK9/ASNS/CDK1/EEF2/GAPDH/MSH6/PIK3CA/MAPK3/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50
## GO:0005198 TUBA1B/MYH11/FN1/RPS6
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/STAT5A/STAT3/PARP1/XIAP/AR/CHEK1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/ACACA/E2F1/HSPA1A/CASP9/PREX1/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/ANXA7/ASNS/CDK1/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 33 33/125
## GO:0002376 GO:0002376 immune system process 60 60/125
## GO:0008152 GO:0008152 metabolic process 110 110/125
## GO:0009987 GO:0009987 cellular process 125 125/125
## GO:0016032 GO:0016032 viral process 12 12/125
## GO:0022414 GO:0022414 reproductive process 32 32/125
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/STAT3/PARP1/AR/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/CDK1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50
## GO:0002376 ESR1/BAP1/G6PD/BCL2/KIT/RB1/ADAR/MYH9/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/STAT3/PARP1/XIAP/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/YWHAE/ARID1A/NDRG1/BID/ERCC1/PRKCD/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/MAPK9/ANXA1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SERPINE1/PIK3CA/MAPK3/RET/RPS6KB1/TFRC/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2
## GO:0008152 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/KRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/STAT5A/STAT3/PARP1/XIAP/AR/CHEK1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/YWHAE/ARID1A/CCNE2/EEF2K/AKT1S1/BID/ERCC1/CHEK2/INPP4B/YWHAB/PRKCD/ACACA/E2F1/HSPA1A/CASP9/PREX1/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/ANXA7/ASNS/CDK1/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD3/SMAD4/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/SQSTM1/WWTR1/DIABLO/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009987 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/STAT5A/STAT3/PARP1/XIAP/AR/CHEK1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/ACACA/E2F1/HSPA1A/CASP9/PREX1/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/ANXA7/ASNS/CDK1/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0016032 BCL2/ADAR/EGFR/JUN/AKT1/GSK3B/ITGA2/HSPA1A/AXL/CAV1/CDK1/TFRC
## GO:0022414 ESR1/ERRFI1/PTEN/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/PARP1/AR/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/CDK1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 82 82/125
## GO:0044423 GO:0044423 virion component 0 0/125
## GO:0110165 GO:0110165 cellular anatomical entity 125 125/125
## geneID
## GO:0032991 ESR1/MET/BAP1/BCL2/KIT/NCOA3/ERBB3/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/STAT5A/STAT3/PARP1/AR/CHEK1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/ARID1A/PEA15/CCNE2/AKT1S1/ERCC1/MYH11/E2F1/HSPA1A/CASP9/AXL/CDKN2A/CAV1/MSH2/CASP3/CCNE1/YAP1/CDK1/EEF2/FOXM1/FN1/GAPDH/MSH6/SMAD3/SMAD4/SERPINE1/PIK3CA/RET/RPS6/TFRC/XRCC1/RAB11A/WWTR1/DIABLO/RICTOR/TP53BP1/RAD50
## GO:0044423
## GO:0110165 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/STAT5A/STAT3/PARP1/XIAP/AR/CHEK1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/ACACA/E2F1/HSPA1A/CASP9/PREX1/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/ANXA7/ASNS/CDK1/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/130
## GO:0003824 GO:0003824 catalytic activity 60 60/130
## GO:0005198 GO:0005198 structural molecule activity 4 4/130
## GO:0005215 GO:0005215 transporter activity 2 2/130
## GO:0005488 GO:0005488 binding 130 130/130
## GO:0009055 GO:0009055 electron transfer activity 0 0/130
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/KIT/NCOA3/ERBB2/KRAS/NRAS/ADAR/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/EEF2/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/INPP4B/PRKCD/RAB25/ACACA/HSPA1A/AXL/PTK2/MSH2/CASP3/CCNE1/ASNS/GAPDH/MSH6/PRDX1/PIK3CA/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50
## GO:0005198 TUBA1B/MYH11/FN1/RPS6
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 38 38/130
## GO:0002376 GO:0002376 immune system process 64 64/130
## GO:0008152 GO:0008152 metabolic process 115 115/130
## GO:0009987 GO:0009987 cellular process 130 130/130
## GO:0016032 GO:0016032 viral process 14 14/130
## GO:0022414 GO:0022414 reproductive process 37 37/130
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/BCL2/KIT/ERBB2/RB1/ADAR/MYH9/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/TFRC/YWHAE/ARID1A/BECN1/NDRG1/BID/ERCC1/PRKCD/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/ANXA1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/SERPINE1/PIK3CA/RET/RPS6KB1/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/INPP4B/YWHAB/PRKCD/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/SQSTM1/WWTR1/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0016032 NOTCH1/BCL2/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/TFRC/BECN1/HSPA1A/AXL/CAV1
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 86 86/130
## GO:0044423 GO:0044423 virion component 0 0/130
## GO:0110165 GO:0110165 cellular anatomical entity 130 130/130
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB2/ERBB3/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/TFRC/ARID1A/BECN1/PEA15/CCNE2/DIABLO/AKT1S1/ERCC1/MYH11/SMAD1/E2F1/HSPA1A/AXL/CAV1/MSH2/CASP3/CCNE1/YAP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/SERPINE1/PIK3CA/RET/RPS6/XRCC1/RAB11A/WWTR1/RICTOR/TP53BP1/RAD50
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/138
## GO:0003824 GO:0003824 catalytic activity 64 64/138
## GO:0005198 GO:0005198 structural molecule activity 4 4/138
## GO:0005215 GO:0005215 transporter activity 2 2/138
## GO:0005488 GO:0005488 binding 138 138/138
## GO:0009055 GO:0009055 electron transfer activity 0 0/138
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/KIT/NCOA3/KRAS/NRAS/ADAR/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/ACVRL1/CHEK2/INPP4B/PRKCD/RAB25/ACACA/ERBB2/HSPA1A/CASP9/AXL/PTK2/MSH2/CASP3/CCNE1/MAPK9/ASNS/EEF2/GAPDH/MSH6/PRDX1/PIK3CA/MAPK3/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50
## GO:0005198 TUBA1B/MYH11/FN1/RPS6
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/E2F1/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/ACVRL1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/ACACA/ERBB2/HSPA1A/CASP9/PREX1/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/TP53/YAP1/XBP1/ANXA7/ASNS/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/VASP/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/PTCH1/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 38 38/138
## GO:0002376 GO:0002376 immune system process 69 69/138
## GO:0008152 GO:0008152 metabolic process 122 122/138
## GO:0009987 GO:0009987 cellular process 138 138/138
## GO:0016032 GO:0016032 viral process 15 15/138
## GO:0022414 GO:0022414 reproductive process 37 37/138
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/PTCH1/RAD50
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/BCL2/KIT/RB1/ADAR/MYH9/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/YWHAE/ARID1A/BECN1/NDRG1/BID/ERCC1/PRKCD/ERBB2/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/MAPK9/ANXA1/TP53/XBP1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6KB1/TFRC/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/E2F1/KRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/AKT1S1/BID/ERCC1/ACVRL1/CHEK2/INPP4B/YWHAB/PRKCD/ACACA/ERBB2/HSPA1A/CASP9/PREX1/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/TP53/YAP1/XBP1/ANXA7/ASNS/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD3/SMAD4/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/SQSTM1/WWTR1/DIABLO/NEK7/RICTOR/PTCH1/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/E2F1/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/ACVRL1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/ACACA/ERBB2/HSPA1A/CASP9/PREX1/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/TP53/YAP1/XBP1/ANXA7/ASNS/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/VASP/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/PTCH1/TP53BP1/FASN/BRAF/LCN2/RAD50
## GO:0016032 NOTCH1/BCL2/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/BECN1/HSPA1A/AXL/CAV1/TP53/TFRC
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/PTCH1/RAD50
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 91 91/138
## GO:0044423 GO:0044423 virion component 0 0/138
## GO:0110165 GO:0110165 cellular anatomical entity 138 138/138
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB3/E2F1/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/ARID1A/BECN1/PEA15/CCNE2/AKT1S1/ERCC1/ACVRL1/MYH11/ERBB2/HSPA1A/CASP9/AXL/CDKN2A/CAV1/MSH2/CASP3/CCNE1/TP53/YAP1/XBP1/EEF2/FOXM1/FN1/GAPDH/MSH6/SMAD3/SMAD4/SERPINE1/PIK3CA/RET/RPS6/TFRC/XRCC1/RAB11A/WWTR1/DIABLO/RICTOR/TP53BP1/RAD50
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/NF2/E2F1/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/ACVRL1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/ACACA/ERBB2/HSPA1A/CASP9/PREX1/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/TP53/YAP1/XBP1/ANXA7/ASNS/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/VASP/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/PTCH1/TP53BP1/FASN/BRAF/LCN2/RAD50
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/142
## GO:0003824 GO:0003824 catalytic activity 64 64/142
## GO:0005198 GO:0005198 structural molecule activity 6 6/142
## GO:0005215 GO:0005215 transporter activity 2 2/142
## GO:0005488 GO:0005488 binding 142 142/142
## GO:0009055 GO:0009055 electron transfer activity 0 0/142
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/KIT/NCOA3/ERBB2/KRAS/NRAS/ADAR/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/EEF2/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/INPP4B/PRKCD/RAB25/ACACA/HSPA1A/AXL/PTK2/MSH2/CASP3/CCNE1/ASNS/GAPDH/MSH6/PRDX1/PIK3CA/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50/TGM2/DIRAS3/VHL/ACVRL1
## GO:0005198 TUBA1B/MYH11/FN1/RPS6/COL6A1/CTNNA1
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/DIRAS3/CTNNA1/GATA3/TTF1/RBM15/TSC1/VHL/ACVRL1
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 42 42/142
## GO:0002376 GO:0002376 immune system process 67 67/142
## GO:0008152 GO:0008152 metabolic process 124 124/142
## GO:0009987 GO:0009987 cellular process 142 142/142
## GO:0016032 GO:0016032 viral process 14 14/142
## GO:0022414 GO:0022414 reproductive process 41 41/142
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/DIRAS3/CTNNA1/GATA3
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/BCL2/KIT/ERBB2/RB1/ADAR/MYH9/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/TFRC/YWHAE/ARID1A/BECN1/NDRG1/BID/ERCC1/PRKCD/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/ANXA1/FN1/GAPDH/MSH6/IGFBP2/PRDX1/SERPINE1/PIK3CA/RET/RPS6KB1/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2/GATA3/RBM15/TSC1
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/INPP4B/YWHAB/PRKCD/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/SQSTM1/WWTR1/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/TGM2/COL6A1/DIRAS3/GATA3/TTF1/RBM15/TSC1/VHL/ACVRL1
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/DIRAS3/CTNNA1/GATA3/TTF1/RBM15/TSC1/VHL/ACVRL1
## GO:0016032 NOTCH1/BCL2/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/TFRC/BECN1/HSPA1A/AXL/CAV1
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/DIRAS3/CTNNA1/GATA3
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 94 94/142
## GO:0044423 GO:0044423 virion component 0 0/142
## GO:0110165 GO:0110165 cellular anatomical entity 142 142/142
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB2/ERBB3/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/TFRC/ARID1A/BECN1/PEA15/CCNE2/DIABLO/AKT1S1/ERCC1/MYH11/SMAD1/E2F1/HSPA1A/AXL/CAV1/MSH2/CASP3/CCNE1/YAP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/SERPINE1/PIK3CA/RET/RPS6/XRCC1/RAB11A/WWTR1/RICTOR/TP53BP1/RAD50/TGM2/COL6A1/CDH2/CTNNA1/GATA3/RBM15/TSC1/ACVRL1
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/PTK2/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/TGM2/COL6A1/CDH2/DIRAS3/CTNNA1/GATA3/TTF1/RBM15/TSC1/VHL/ACVRL1
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/137
## GO:0003824 GO:0003824 catalytic activity 63 63/137
## GO:0005198 GO:0005198 structural molecule activity 5 5/137
## GO:0005215 GO:0005215 transporter activity 2 2/137
## GO:0005488 GO:0005488 binding 137 137/137
## GO:0009055 GO:0009055 electron transfer activity 0 0/137
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 MET/BAP1/AKT2/PTEN/G6PD/KIT/NCOA3/KRAS/NRAS/ADAR/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/PARP1/XIAP/CHEK1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/PRKCD/RAB25/ACACA/HSPA1A/CASP9/AXL/PTK2/MSH2/CASP3/CCNE1/MAPK9/ASNS/CDK1/EEF2/GAPDH/MSH6/PRDX1/PIK3CA/MAPK3/RET/RPS6KB1/XRCC1/RAB11A/NEK7/INPP4B/FASN/BRAF/RAD50/TGM2/ATM/VHL
## GO:0005198 TUBA1B/MYH11/FN1/RPS6/COL6A1
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/STAT5A/STAT3/PARP1/XIAP/AR/CHEK1/DVL3/EIF4E/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/YWHAB/PRKCD/RAB25/PRRT2/ACACA/E2F1/HSPA1A/CASP9/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/ASNS/CDK1/CTNNB1/EEF2/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/CDH2/COL6A1/SERPINE1/TGM2/GATA3/ATM/RBM15/VHL/NF2/TSC1/PREX1/TTF1
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 37 37/137
## GO:0002376 GO:0002376 immune system process 66 66/137
## GO:0008152 GO:0008152 metabolic process 120 120/137
## GO:0009987 GO:0009987 cellular process 137 137/137
## GO:0016032 GO:0016032 viral process 12 12/137
## GO:0022414 GO:0022414 reproductive process 36 36/137
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/STAT3/PARP1/AR/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/CDK1/CTNNB1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/GATA3/ATM
## GO:0002376 ESR1/BAP1/G6PD/BCL2/KIT/RB1/ADAR/MYH9/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/STAT3/PARP1/XIAP/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/YWHAE/ARID1A/BID/ERCC1/PRKCD/HSPA1A/AXL/PTK2/CAV1/MSH2/CASP3/MAPK9/ANXA1/CTNNB1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/PRDX1/PIK3CA/MAPK3/RET/RPS6KB1/TFRC/SQSTM1/GAB2/NDRG1/NEK7/TP53BP1/BRAF/LCN2/SERPINE1/GATA3/ATM/RBM15/TSC1/PREX1
## GO:0008152 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/KRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/STAT5A/STAT3/PARP1/XIAP/AR/CHEK1/DVL3/EIF4E/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/YWHAE/ARID1A/CCNE2/EEF2K/AKT1S1/BID/ERCC1/CHEK2/YWHAB/PRKCD/ACACA/E2F1/HSPA1A/CASP9/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/ASNS/CDK1/CTNNB1/EEF2/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/SMAD3/SMAD4/PRDX1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/SQSTM1/WWTR1/DIABLO/NEK7/RICTOR/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50/COL6A1/SERPINE1/TGM2/GATA3/ATM/RBM15/VHL/NF2/TSC1/PREX1/TTF1
## GO:0009987 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/STAT5A/STAT3/PARP1/XIAP/AR/CHEK1/DVL3/EIF4E/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/YWHAB/PRKCD/RAB25/PRRT2/ACACA/E2F1/HSPA1A/CASP9/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/ASNS/CDK1/CTNNB1/EEF2/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/CDH2/COL6A1/SERPINE1/TGM2/GATA3/ATM/RBM15/VHL/NF2/TSC1/PREX1/TTF1
## GO:0016032 BCL2/ADAR/EGFR/JUN/AKT1/GSK3B/ITGA2/HSPA1A/AXL/CAV1/CDK1/TFRC
## GO:0022414 ESR1/ERRFI1/PTEN/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/PARP1/AR/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/CDK1/CTNNB1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/GATA3/ATM
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 90 90/137
## GO:0044423 GO:0044423 virion component 0 0/137
## GO:0110165 GO:0110165 cellular anatomical entity 137 137/137
## geneID
## GO:0032991 ESR1/MET/BAP1/BCL2/KIT/NCOA3/ERBB3/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/STAT5A/STAT3/PARP1/AR/CHEK1/DVL3/EIF4E/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/ARID1A/PEA15/CCNE2/AKT1S1/ERCC1/MYH11/E2F1/HSPA1A/CASP9/AXL/CDKN2A/CAV1/MSH2/CASP3/CCNE1/YAP1/CDK1/CTNNB1/EEF2/EIF4G1/FOXM1/FN1/GAPDH/MSH6/SMAD3/SMAD4/PIK3CA/RET/RPS6/TFRC/XRCC1/RAB11A/WWTR1/DIABLO/RICTOR/TP53BP1/RAD50/CDH2/COL6A1/SERPINE1/TGM2/GATA3/ATM/RBM15/TSC1
## GO:0044423
## GO:0110165 ESR1/MET/BAP1/ERRFI1/AKT2/PTEN/G6PD/BCL2/KIT/NCOA3/ERBB3/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/STAT5A/STAT3/PARP1/XIAP/AR/CHEK1/DVL3/EIF4E/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/PEA15/CCNE2/TUBA1B/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/YWHAB/PRKCD/RAB25/PRRT2/ACACA/E2F1/HSPA1A/CASP9/AXL/PTK2/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/ASNS/CDK1/CTNNB1/EEF2/EIF4EBP1/EIF4G1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/NDRG1/WWTR1/ANLN/DIABLO/NEK7/RICTOR/INPP4B/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/CDH2/COL6A1/SERPINE1/TGM2/GATA3/ATM/RBM15/VHL/NF2/TSC1/PREX1/TTF1
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/148
## GO:0003824 GO:0003824 catalytic activity 66 66/148
## GO:0005198 GO:0005198 structural molecule activity 6 6/148
## GO:0005215 GO:0005215 transporter activity 2 2/148
## GO:0005488 GO:0005488 binding 148 148/148
## GO:0009055 GO:0009055 electron transfer activity 0 0/148
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/MAPK14/KIT/NCOA3/ERBB2/KRAS/NRAS/ADAR/PTK2/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/EEF2/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/INPP4B/RAB11B/PRKCD/RAB25/ACACA/HSPA1A/AXL/MSH2/CASP3/CCNE1/ASNS/GAPDH/MSH6/PRDX1/PIK3CA/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50/TGM2/DIRAS3/VHL/ACVRL1
## GO:0005198 TUBA1B/MYH11/FN1/RPS6/COL6A1/CTNNA1
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/MAPK14/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/RAB11B/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/CDH1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/NFE2L2/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TSC2/TP53BP1/FASN/BRAF/LCN2/RAD50/TGM2/SYP/COL6A1/DIRAS3/CTNNA1/CDH2/RBM3/GATA3/TTF1/RBM15/TSC1/VHL/ACVRL1
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 42 42/148
## GO:0002376 GO:0002376 immune system process 69 69/148
## GO:0008152 GO:0008152 metabolic process 130 130/148
## GO:0009987 GO:0009987 cellular process 148 148/148
## GO:0016032 GO:0016032 viral process 14 14/148
## GO:0022414 GO:0022414 reproductive process 41 41/148
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/DIRAS3/CTNNA1/GATA3
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/MAPK14/BCL2/KIT/ERBB2/RB1/ADAR/MYH9/PTK2/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/TFRC/YWHAE/ARID1A/BECN1/NDRG1/BID/ERCC1/PRKCD/HSPA1A/PREX1/AXL/CAV1/MSH2/CASP3/ANXA1/FN1/GAPDH/MSH6/IGFBP2/NFE2L2/PRDX1/SERPINE1/PIK3CA/RET/RPS6KB1/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2/GATA3/RBM15/TSC1
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/MAPK14/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/INPP4B/YWHAB/RAB11B/PRKCD/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/CDH1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD4/NFE2L2/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/SQSTM1/WWTR1/NEK7/RICTOR/TSC2/TP53BP1/FASN/BRAF/LCN2/RAD50/TGM2/COL6A1/DIRAS3/RBM3/GATA3/TTF1/RBM15/TSC1/VHL/ACVRL1
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/MAPK14/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/RAB11B/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/CDH1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/NFE2L2/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TSC2/TP53BP1/FASN/BRAF/LCN2/RAD50/TGM2/SYP/COL6A1/DIRAS3/CTNNA1/CDH2/RBM3/GATA3/TTF1/RBM15/TSC1/VHL/ACVRL1
## GO:0016032 NOTCH1/BCL2/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/TFRC/BECN1/HSPA1A/AXL/CAV1
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/AR/CASP8/CDK1/CTNNB1/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/SMAD1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/DIRAS3/CTNNA1/GATA3
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 98 98/148
## GO:0044423 GO:0044423 virion component 0 0/148
## GO:0110165 GO:0110165 cellular anatomical entity 148 148/148
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB2/ERBB3/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/TFRC/ARID1A/BECN1/PEA15/CCNE2/DIABLO/AKT1S1/ERCC1/MYH11/SMAD1/E2F1/HSPA1A/AXL/CAV1/MSH2/CASP3/CCNE1/YAP1/CDH1/FOXM1/FN1/GAPDH/MSH6/SMAD4/NFE2L2/SERPINE1/PIK3CA/RET/RPS6/XRCC1/RAB11A/WWTR1/RICTOR/TSC2/TP53BP1/RAD50/TGM2/COL6A1/CTNNA1/CDH2/RBM3/GATA3/RBM15/TSC1/ACVRL1
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/MAPK14/BCL2/KIT/NCOA3/ERBB2/ERBB3/NF2/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EEF2/EIF4E/EIF4G1/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/TFRC/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/DIABLO/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/RAB11B/PRKCD/RAB25/PRRT2/MACC1/ACACA/SMAD1/E2F1/HSPA1A/PREX1/AXL/CAV1/MSH2/CASP3/CCNE1/ANXA1/TFF1/YAP1/CDH1/ANXA7/ASNS/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD4/NFE2L2/PRDX1/SERPINE1/PIK3CA/RET/RPS6/RPS6KB1/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/NEK7/RICTOR/TSC2/TP53BP1/FASN/BRAF/LCN2/RAD50/TGM2/SYP/COL6A1/DIRAS3/CTNNA1/CDH2/RBM3/GATA3/TTF1/RBM15/TSC1/VHL/ACVRL1
## ID Description Count GeneRatio
## GO:0003774 GO:0003774 cytoskeletal motor activity 2 2/147
## GO:0003824 GO:0003824 catalytic activity 67 67/147
## GO:0005198 GO:0005198 structural molecule activity 5 5/147
## GO:0005215 GO:0005215 transporter activity 2 2/147
## GO:0005488 GO:0005488 binding 147 147/147
## GO:0009055 GO:0009055 electron transfer activity 0 0/147
## geneID
## GO:0003774 MYH9/MYH11
## GO:0003824 AKT2/BAP1/MET/PTEN/G6PD/KIT/NCOA3/HSPA1A/KRAS/NRAS/ADAR/PTK2/CCND1/CDKN1A/EGFR/PIK3R1/EZH2/RAF1/PTGS2/AKT1/VHL/ATM/PARP1/XIAP/CASP8/CDK1/CHEK1/MTOR/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/TUBA1B/EEF2K/ERCC1/CHEK2/INPP4B/RAB11B/PRKCD/RAB25/ACACA/CASP9/AXL/MSH2/CASP3/CCNE1/MAPK9/ASNS/EEF2/GAPDH/MSH6/PRDX1/PIK3CA/MAPK3/RET/RPS6KB1/XRCC1/RAB11A/NEK7/FASN/BRAF/RAD50/TGM2/DIRAS3
## GO:0005198 TUBA1B/MYH11/FN1/RPS6/COL6A1
## GO:0005215 BCL2/IGF1R
## GO:0005488 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/RAB11B/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/CASP9/PREX1/AXL/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/CDH1/ANXA7/ASNS/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/COL6A1/CDH2/TGM2/DIRAS3/GATA3/RBM15/TSC1/NF2/TTF1/XBP1
## GO:0009055
## ID Description Count GeneRatio
## GO:0000003 GO:0000003 reproduction 41 41/147
## GO:0002376 GO:0002376 immune system process 71 71/147
## GO:0008152 GO:0008152 metabolic process 130 130/147
## GO:0009987 GO:0009987 cellular process 147 147/147
## GO:0016032 GO:0016032 viral process 14 14/147
## GO:0022414 GO:0022414 reproductive process 40 40/147
## geneID
## GO:0000003 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/STAT3/PARP1/AR/CASP8/CDK1/CTNNB1/MTOR/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/DIRAS3/GATA3
## GO:0002376 ESR1/BAP1/NOTCH1/G6PD/BCL2/KIT/HSPA1A/RB1/ADAR/MYH9/PTK2/CDKN1A/MYC/PIK3R1/BCL2L11/EZH2/PIK3R2/RAF1/ETS1/FOXO3/YWHAZ/AKT1/ATM/STAT3/PARP1/XIAP/CASP8/CTNNB1/MTOR/IGF1R/ITGA2/MAPT/PRKCA/MAPK1/MAPK8/YWHAE/ARID1A/BECN1/NDRG1/BID/ERCC1/PRKCD/PREX1/AXL/CAV1/MSH2/CASP3/MAPK9/ANXA1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6KB1/TFRC/SQSTM1/GAB2/NEK7/TP53BP1/BRAF/LCN2/GATA3/RBM15/TSC1/XBP1
## GO:0008152 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/HSPA1A/KRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/EZH2/PIK3R2/RAF1/PTGS2/ETS1/SHC1/FOXO3/YWHAZ/AKT1/VHL/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/RAD51/SRSF1/YWHAE/ARID1A/BECN1/CCNE2/EEF2K/AKT1S1/BID/ERCC1/CHEK2/INPP4B/YWHAB/RAB11B/PRKCD/MACC1/ACACA/E2F1/CASP9/PREX1/AXL/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/CDH1/ANXA7/ASNS/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/SMAD3/SMAD4/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/SQSTM1/WWTR1/DIABLO/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/COL6A1/TGM2/DIRAS3/GATA3/RBM15/TSC1/NF2/TTF1/XBP1
## GO:0009987 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/RAB11B/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/CASP9/PREX1/AXL/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/CDH1/ANXA7/ASNS/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/COL6A1/CDH2/TGM2/DIRAS3/GATA3/RBM15/TSC1/NF2/TTF1/XBP1
## GO:0016032 NOTCH1/BCL2/HSPA1A/ADAR/EGFR/JUN/AKT1/CDK1/GSK3B/ITGA2/BECN1/AXL/CAV1/TFRC
## GO:0022414 ESR1/ERRFI1/PTEN/NOTCH1/BCL2/KIT/RB1/MYH9/CDKN1B/EGFR/BCL2L11/PTGS2/FOXO3/AKT1/BCL2L1/ATM/PARP1/AR/CASP8/CDK1/CTNNB1/MTOR/IGF1R/ITGA2/RAD51/CCNE2/ERCC1/AXL/MSH2/CASP3/CCNE1/MSH6/IGFBP2/SMAD4/PIK3CA/RPS6KB1/RAD50/COL6A1/DIRAS3/GATA3
## ID Description Count GeneRatio
## GO:0032991 GO:0032991 protein-containing complex 96 96/147
## GO:0044423 GO:0044423 virion component 0 0/147
## GO:0110165 GO:0110165 cellular anatomical entity 147 147/147
## geneID
## GO:0032991 ESR1/BAP1/MET/NOTCH1/BCL2/KIT/NCOA3/ERBB3/HSPA1A/RB1/ADAR/MYH9/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/PTGS2/ETS1/SHC1/FOXO3/AKT1/BCL2L1/ATM/STAT5A/STAT3/PARP1/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/PXN/RAD51/SRSF1/ARID1A/BECN1/PEA15/CCNE2/AKT1S1/ERCC1/MYH11/E2F1/CASP9/AXL/CDKN2A/CAV1/MSH2/CASP3/CCNE1/YAP1/CDH1/EEF2/FOXM1/FN1/GAPDH/MSH6/SMAD3/SMAD4/SERPINE1/PIK3CA/RET/RPS6/TFRC/XRCC1/RAB11A/WWTR1/DIABLO/RICTOR/TP53BP1/RAD50/COL6A1/CDH2/TGM2/GATA3/RBM15/TSC1/XBP1
## GO:0044423
## GO:0110165 ESR1/AKT2/BAP1/ERRFI1/MET/PTEN/NOTCH1/G6PD/BCL2/KIT/NCOA3/ERBB3/HSPA1A/KRAS/NRAS/RB1/ADAR/PDCD4/MYH9/PTK2/CCND1/CDKN1A/CDKN1B/IRS1/MYC/EGFR/JUN/PIK3R1/NOTCH3/BCL2L11/EZH2/PIK3R2/RAF1/PTGS2/ETS1/STMN1/SHC1/FOXO3/YWHAZ/AKT1/VHL/BCL2L1/ATM/STAT5A/STAT3/PARP1/XIAP/AR/CASP8/CDK1/CHEK1/CTNNB1/DVL3/EIF4E/EIF4G1/MTOR/GSK3B/IGF1R/ITGA2/MAPT/YBX1/PRKAA1/PRKCA/MAPK1/MAPK8/PXN/RAD51/SRSF1/YWHAE/ARID1A/BECN1/PEA15/CCNE2/TUBA1B/NDRG1/EEF2K/AKT1S1/BID/ERCC1/CHEK2/MYH11/INPP4B/YWHAB/RAB11B/PRKCD/RAB25/PRRT2/MACC1/ACACA/E2F1/CASP9/PREX1/AXL/CDKN2A/CAV1/MSH2/CASP3/CCNE1/MAPK9/ANXA1/TFF1/YAP1/CDH1/ANXA7/ASNS/EEF2/EIF4EBP1/FOXM1/FN1/GAPDH/MSH6/IGFBP2/SMAD3/SMAD4/PRDX1/SERPINE1/PIK3CA/MAPK3/RET/RPS6/RPS6KB1/TFRC/XRCC1/RAB11A/SQSTM1/GAB2/WWTR1/ANLN/DIABLO/NEK7/RICTOR/TP53BP1/FASN/BRAF/LCN2/RAD50/SYP/COL6A1/CDH2/TGM2/DIRAS3/GATA3/RBM15/TSC1/NF2/TTF1/XBP1barplot(ggo_MF[[1]], title = "groupGO, Molecular Function, \n RPPAArray, FDR = 0.9")
barplot(ggo_MF[[2]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, FDR = 1-1e-14")
barplot(ggo_MF[[3]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, FDR = 1-1e-6")
barplot(ggo_MF[[4]], title = "groupGO, Molecular Function, \n miRNASeqGene, FDR = 1-1e-13")
barplot(ggo_MF[[5]], title = "groupGO, Molecular Function, \n miRNASeqGene, FDR = 1-1e-6")
barplot(ggo_MF[[6]], title = "groupGO, Molecular Function, \n All datasets, FDR = 1-1e-14")
barplot(ggo_MF[[7]], title = "groupGO, Molecular Function, \n All datasets, FDR = 1-1e-6")
barplot(ggo_MF[[8]], title = "groupGO, Molecular Function, \n RPPAArray, Surviving Patients, FDR = 0.9")
barplot(ggo_MF[[9]], title = "groupGO, Molecular Function, \n RPPAArray, Deceased Patients, FDR = 0.9")
barplot(ggo_MF[[10]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")
barplot(ggo_MF[[11]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")
barplot(ggo_MF[[12]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_MF[[13]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")
barplot(ggo_MF[[14]], title = "groupGO, Molecular Function, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-13")
barplot(ggo_MF[[15]], title = "groupGO, Molecular Function, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-13")
barplot(ggo_MF[[16]], title = "groupGO, Molecular Function, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_MF[[17]], title = "groupGO, Molecular Function, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
barplot(ggo_MF[[18]], title = "groupGO, Molecular Function, \n All datasets, Surviving Patients, FDR = 1-1e-14")
barplot(ggo_MF[[19]], title = "groupGO, Molecular Function, \n All datasets, Deceased Patients, FDR = 1-1e-14")
barplot(ggo_MF[[20]], title = "groupGO, Molecular Function, \n All datasets, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_MF[[21]], title = "groupGO, Molecular Function, \n All datasets, Deceased Patients, FDR = 1-1e-6")
barplot(ggo_BP[[1]], title = "groupGO, Biological Process, \n RPPAArray, FDR = 0.9")
barplot(ggo_BP[[2]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, FDR = 1-1e-14")
barplot(ggo_BP[[3]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, FDR = 1-1e-6")
barplot(ggo_BP[[4]], title = "groupGO, Biological Process, \n miRNASeqGene, FDR = 1-1e-13")
barplot(ggo_BP[[5]], title = "groupGO, Biological Process, \n miRNASeqGene, FDR = 1-1e-6")
barplot(ggo_BP[[6]], title = "groupGO, Biological Process, \n All datasets, FDR = 1-1e-14")
barplot(ggo_BP[[7]], title = "groupGO, Biological Process, \n All datasets, FDR = 1-1e-6")
barplot(ggo_BP[[8]], title = "groupGO, Biological Process, \n RPPAArray, Surviving Patients, FDR = 0.9")
barplot(ggo_BP[[9]], title = "groupGO, Biological Process, \n RPPAArray, Deceased Patients, FDR = 0.9")
barplot(ggo_BP[[10]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")
barplot(ggo_BP[[11]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")
barplot(ggo_BP[[12]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_BP[[13]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")
barplot(ggo_BP[[14]], title = "groupGO, Biological Process, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-14")
barplot(ggo_BP[[15]], title = "groupGO, Biological Process, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-14")
barplot(ggo_BP[[16]], title = "groupGO, Biological Process, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_BP[[17]], title = "groupGO, Biological Process, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
barplot(ggo_BP[[18]], title = "groupGO, Biological Process, \n All datasets, Surviving Patients, FDR = 1-1e-14")
barplot(ggo_BP[[19]], title = "groupGO, Biological Process, \n All datasets, Deceased Patients, FDR = 1-1e-14")
barplot(ggo_BP[[20]], title = "groupGO, Biological Process, \n All datasets, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_BP[[21]], title = "groupGO, Biological Process, \n All datasets, Deceased Patients, FDR = 1-1e-6")
barplot(ggo_CC[[1]], title = "groupGO, Cellular Component, \n RPPAArray, FDR = 0.9")
barplot(ggo_CC[[2]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, FDR = 1-1e-14")
barplot(ggo_CC[[3]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, FDR = 1-1e-6")
barplot(ggo_CC[[4]], title = "groupGO, Cellular Component, \n miRNASeqGene, FDR = 1-1e-13")
barplot(ggo_CC[[5]], title = "groupGO, Cellular Component, \n miRNASeqGene, FDR = 1-1e-6")
barplot(ggo_CC[[6]], title = "groupGO, Cellular Component, \n All datasets, FDR = 1-1e-14")
barplot(ggo_CC[[7]], title = "groupGO, Cellular Component, \n All datasets, FDR = 1-1e-6")
barplot(ggo_CC[[8]], title = "groupGO, Cellular Component, \n RPPAArray, Surviving Patients, FDR = 0.9")
barplot(ggo_CC[[9]], title = "groupGO, Cellular Component, \n RPPAArray, Deceased Patients, FDR = 0.9")
barplot(ggo_CC[[10]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")
barplot(ggo_CC[[11]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")
barplot(ggo_CC[[12]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_CC[[13]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")
barplot(ggo_CC[[14]], title = "groupGO, Cellular Component, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-13")
barplot(ggo_CC[[15]], title = "groupGO, Cellular Component, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-13")
barplot(ggo_CC[[16]], title = "groupGO, Cellular Component, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_CC[[17]], title = "groupGO, Cellular Component, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
barplot(ggo_CC[[18]], title = "groupGO, Cellular Component, \n All datasets, Surviving Patients, FDR = 1-1e-14")
barplot(ggo_CC[[19]], title = "groupGO, Cellular Component, \n All datasets, Deceased Patients, FDR = 1-1e-14")
barplot(ggo_CC[[20]], title = "groupGO, Cellular Component, \n All datasets, Surviving Patients, FDR = 1-1e-6")
barplot(ggo_CC[[21]], title = "groupGO, Cellular Component, \n All datasets, Deceased Patients, FDR = 1-1e-6")
B. GO Over-Representation
ego_MF <- list()#GO enrichment of a geneset for Molecular Function
ego_BP <- list()#GO enrichment of a geneset for Biological Process
ego_CC <- list()#GO enrichment of a geneset for Cellular Component
for(z in 1:length(geneNames)){
print(z)
input <- geneNames[[z]]
ego_MF[[z]] <- enrichGO(
gene = input,
OrgDb = org.Hs.eg.db,
ont = "MF",
pAdjustMethod = "BH",
keyType="SYMBOL",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05,
minGSSize = 2,
readable = TRUE)
ego_BP[[z]] <- enrichGO(
gene = input,
OrgDb = org.Hs.eg.db,
ont = "BP",
pAdjustMethod = "BH",
keyType="SYMBOL",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05,
minGSSize = 2,
readable = TRUE)
ego_CC[[z]] <- enrichGO(
gene = input,
OrgDb = org.Hs.eg.db,
ont = "CC",
pAdjustMethod = "BH",
keyType="SYMBOL",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05,
minGSSize = 2,
readable = TRUE)
}## [1] 1
## [1] 2
## [1] 3
## [1] 4
## [1] 5
## [1] 6
## [1] 7
## [1] 8
## [1] 9
## [1] 10
## [1] 11
## [1] 12
## [1] 13
## [1] 14
## [1] 15
## [1] 16
## [1] 17
## [1] 18
## [1] 19
## [1] 20
## [1] 21for(z in 1:length(geneNames)){
print(head(ego_MF[[z]]))
print(head(ego_BP[[z]]))
print(head(ego_CC[[z]]))
}## ID Description GeneRatio
## GO:0032143 GO:0032143 single thymine insertion binding 2/14
## GO:0032137 GO:0032137 guanine/thymine mispair binding 2/14
## GO:0032142 GO:0032142 single guanine insertion binding 2/14
## GO:0032138 GO:0032138 single base insertion or deletion binding 2/14
## GO:0032135 GO:0032135 DNA insertion or deletion binding 2/14
## GO:0032405 GO:0032405 MutLalpha complex binding 2/14
## BgRatio pvalue p.adjust qvalue geneID Count
## GO:0032143 2/18522 5.305412e-07 8.060742e-05 3.014405e-05 MSH6/MSH2 2
## GO:0032137 3/18522 1.590936e-06 8.060742e-05 3.014405e-05 MSH6/MSH2 2
## GO:0032142 3/18522 1.590936e-06 8.060742e-05 3.014405e-05 MSH6/MSH2 2
## GO:0032138 4/18522 3.180497e-06 1.208589e-04 4.519654e-05 MSH6/MSH2 2
## GO:0032135 6/18522 7.944376e-06 2.012575e-04 7.526251e-05 MSH6/MSH2 2
## GO:0032405 6/18522 7.944376e-06 2.012575e-04 7.526251e-05 MSH6/MSH2 2
## ID
## GO:0051053 GO:0051053
## GO:0002562 GO:0002562
## GO:0016444 GO:0016444
## GO:0002520 GO:0002520
## GO:0002200 GO:0002200
## GO:0010165 GO:0010165
## Description
## GO:0051053 negative regulation of DNA metabolic process
## GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus
## GO:0016444 somatic cell DNA recombination
## GO:0002520 immune system development
## GO:0002200 somatic diversification of immune receptors
## GO:0010165 response to X-ray
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0051053 5/14 142/18888 4.242310e-08 5.387733e-05 2.228329e-05
## GO:0002562 4/14 70/18888 1.683461e-07 5.968005e-05 2.468325e-05
## GO:0016444 4/14 70/18888 1.683461e-07 5.968005e-05 2.468325e-05
## GO:0002520 5/14 197/18888 2.175939e-07 5.968005e-05 2.468325e-05
## GO:0002200 4/14 76/18888 2.349608e-07 5.968005e-05 2.468325e-05
## GO:0010165 3/14 28/18888 1.050419e-06 2.223388e-04 9.195776e-05
## geneID Count
## GO:0051053 GATA3/ATM/TTF1/MSH6/MSH2 5
## GO:0002562 TFRC/ATM/MSH6/MSH2 4
## GO:0016444 TFRC/ATM/MSH6/MSH2 4
## GO:0002520 TFRC/GATA3/ATM/MSH6/MSH2 5
## GO:0002200 TFRC/ATM/MSH6/MSH2 4
## GO:0010165 GATA3/ATM/MSH2 3
## ID Description GeneRatio BgRatio pvalue
## GO:0032301 GO:0032301 MutSalpha complex 2/14 2/19894 4.598847e-07
## GO:0032300 GO:0032300 mismatch repair complex 2/14 11/19894 2.520226e-05
## GO:0042470 GO:0042470 melanosome 3/14 112/19894 6.043424e-05
## GO:0048770 GO:0048770 pigment granule 3/14 112/19894 6.043424e-05
## GO:0032302 GO:0032302 MutSbeta complex 1/14 2/19894 1.407000e-03
## GO:0097452 GO:0097452 GAIT complex 1/14 4/19894 2.812161e-03
## p.adjust qvalue geneID Count
## GO:0032301 2.759308e-05 1.694312e-05 MSH6/MSH2 2
## GO:0032300 7.560678e-04 4.642522e-04 MSH6/MSH2 2
## GO:0042470 9.065136e-04 5.566311e-04 FASN/MYH11/TFRC 3
## GO:0048770 9.065136e-04 5.566311e-04 FASN/MYH11/TFRC 3
## GO:0032302 1.688400e-02 1.036737e-02 MSH2 1
## GO:0097452 2.812161e-02 1.726765e-02 GAPDH 1
## ID Description GeneRatio
## GO:0045296 GO:0045296 cadherin binding 13/46
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 10/46
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 9/46
## GO:0045309 GO:0045309 protein phosphorylated amino acid binding 5/46
## GO:0140311 GO:0140311 protein sequestering activity 4/46
## GO:0019903 GO:0019903 protein phosphatase binding 6/46
## BgRatio pvalue p.adjust qvalue
## GO:0045296 333/18522 9.692270e-13 2.694451e-10 1.316108e-10
## GO:0044389 324/18522 5.449804e-09 7.575228e-07 3.700130e-07
## GO:0031625 305/18522 5.107424e-08 4.732879e-06 2.311781e-06
## GO:0045309 59/18522 3.421023e-07 2.377611e-05 1.161347e-05
## GO:0140311 29/18522 7.555303e-07 4.200748e-05 2.051861e-05
## GO:0019903 142/18522 1.329046e-06 6.157914e-05 3.007841e-05
## geneID
## GO:0045296 EEF2/HSPA1A/CTNNB1/CDH2/FASN/CTNNA1/NDRG1/ANXA1/YWHAZ/YWHAB/MYH9/YWHAE/KDR
## GO:0044389 SQSTM1/HSPA1A/CTNNB1/TUBA1B/CDKN1A/ERBB3/YWHAZ/YWHAE/PARP1/CCNB1
## GO:0031625 SQSTM1/HSPA1A/CTNNB1/TUBA1B/CDKN1A/ERBB3/YWHAZ/YWHAE/PARP1
## GO:0045309 PIK3R1/YWHAZ/YWHAB/PIK3R2/YWHAE
## GO:0140311 SQSTM1/CDKN1A/YWHAZ/YWHAE
## GO:0019903 CTNNB1/CDH2/PIK3R1/PXN/PIK3R2/YWHAE
## Count
## GO:0045296 13
## GO:0044389 10
## GO:0031625 9
## GO:0045309 5
## GO:0140311 4
## GO:0019903 6
## ID Description
## GO:0034504 GO:0034504 protein localization to nucleus
## GO:0031400 GO:0031400 negative regulation of protein modification process
## GO:0051402 GO:0051402 neuron apoptotic process
## GO:1900180 GO:1900180 regulation of protein localization to nucleus
## GO:0030099 GO:0030099 myeloid cell differentiation
## GO:0097305 GO:0097305 response to alcohol
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0034504 10/46 311/18888 3.059074e-09 5.478249e-06 2.714232e-06
## GO:0031400 11/46 426/18888 4.430448e-09 5.478249e-06 2.714232e-06
## GO:0051402 9/46 292/18888 2.976501e-08 2.453629e-05 1.215666e-05
## GO:1900180 7/46 144/18888 5.397589e-08 3.337059e-05 1.653367e-05
## GO:0030099 10/46 439/18888 8.010214e-08 3.961852e-05 1.962924e-05
## GO:0097305 8/46 259/18888 1.865836e-07 7.138999e-05 3.537061e-05
## geneID
## GO:0034504 SQSTM1/PIK3R1/CDKN1A/CTNNA1/TFRC/YWHAZ/PIK3R2/YWHAE/PARP1/CDK1
## GO:0031400 SQSTM1/HSPA1A/CTNNB1/G6PD/CDKN1A/PDCD4/ADAR/YWHAB/ERRFI1/EIF4G1/YWHAE
## GO:0051402 GAPDH/CTNNB1/CCND1/COL6A1/G6PD/ERBB3/PARP1/KDR/BCL2L1
## GO:1900180 PIK3R1/CTNNA1/TFRC/YWHAZ/PIK3R2/PARP1/CDK1
## GO:0030099 HSPA1A/CTNNB1/FASN/PRKCA/PIK3R1/G6PD/ADAR/TFRC/MYH9/PARP1
## GO:0097305 CTNNB1/G6PD/CDKN1A/CTNNA1/EIF4G1/PARP1/CDK1/BCL2L1
## Count
## GO:0034504 10
## GO:0031400 11
## GO:0051402 9
## GO:1900180 7
## GO:0030099 10
## GO:0097305 8
## ID Description GeneRatio BgRatio pvalue
## GO:0005925 GO:0005925 focal adhesion 13/46 421/19894 7.670385e-12
## GO:0030055 GO:0030055 cell-substrate junction 13/46 431/19894 1.029085e-11
## GO:0005912 GO:0005912 adherens junction 6/46 188/19894 4.498552e-06
## GO:0097125 GO:0097125 cyclin B1-CDK1 complex 2/46 2/19894 5.230557e-06
## GO:0042470 GO:0042470 melanosome 5/46 112/19894 5.894996e-06
## GO:0048770 GO:0048770 pigment granule 5/46 112/19894 5.894996e-06
## p.adjust qvalue
## GO:0005925 1.281211e-09 6.120349e-10
## GO:0030055 1.281211e-09 6.120349e-10
## GO:0005912 2.446423e-04 1.168657e-04
## GO:0097125 2.446423e-04 1.168657e-04
## GO:0042470 2.446423e-04 1.168657e-04
## GO:0048770 2.446423e-04 1.168657e-04
## geneID
## GO:0005925 HSPA1A/CTNNB1/TGM2/CDH2/CTNNA1/ANXA1/YWHAZ/YWHAB/PXN/PIK3R2/ITGA2/MYH9/YWHAE
## GO:0030055 HSPA1A/CTNNB1/TGM2/CDH2/CTNNA1/ANXA1/YWHAZ/YWHAB/PXN/PIK3R2/ITGA2/MYH9/YWHAE
## GO:0005912 CTNNB1/CDH2/CTNNA1/NDRG1/ANXA1/MYH9
## GO:0097125 CDK1/CCNB1
## GO:0042470 FASN/TFRC/YWHAZ/YWHAB/YWHAE
## GO:0048770 FASN/TFRC/YWHAZ/YWHAB/YWHAE
## Count
## GO:0005925 13
## GO:0030055 13
## GO:0005912 6
## GO:0097125 2
## GO:0042470 5
## GO:0048770 5
## ID Description GeneRatio
## GO:0045296 GO:0045296 cadherin binding 16/55
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 11/55
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 10/55
## GO:0045309 GO:0045309 protein phosphorylated amino acid binding 6/55
## GO:0051219 GO:0051219 phosphoprotein binding 6/55
## GO:0019207 GO:0019207 kinase regulator activity 8/55
## BgRatio pvalue p.adjust qvalue
## GO:0045296 333/18522 1.312656e-15 4.161119e-13 1.948258e-13
## GO:0044389 324/18522 2.387925e-09 3.784861e-07 1.772092e-07
## GO:0031625 305/18522 1.922313e-08 1.637936e-06 7.668901e-07
## GO:0045309 59/18522 2.066796e-08 1.637936e-06 7.668901e-07
## GO:0051219 93/18522 3.236654e-07 2.052039e-05 9.607752e-06
## GO:0019207 270/18522 1.237087e-06 6.535943e-05 3.060162e-05
## geneID
## GO:0045296 HSPA1A/EEF2/CTNNB1/CDH2/FASN/ANXA1/NDRG1/CTNNA1/YWHAZ/MYH9/YWHAE/YWHAB/PRDX1/ANLN/PARK7/KDR
## GO:0044389 SQSTM1/HSPA1A/CTNNB1/ERBB3/CDKN1A/TUBA1B/YWHAZ/YWHAE/CCNB1/JUN/PARP1
## GO:0031625 SQSTM1/HSPA1A/CTNNB1/ERBB3/CDKN1A/TUBA1B/YWHAZ/YWHAE/JUN/PARP1
## GO:0045309 PIK3R1/PIK3R2/YWHAZ/YWHAE/YWHAB/SHC1
## GO:0051219 PIK3R1/PIK3R2/YWHAZ/YWHAE/YWHAB/SHC1
## GO:0019207 ERBB3/PIK3R1/CDKN1A/CCND1/PIK3R2/CCNB1/YWHAB/AKT1
## Count
## GO:0045296 16
## GO:0044389 11
## GO:0031625 10
## GO:0045309 6
## GO:0051219 6
## GO:0019207 8
## ID Description
## GO:0034504 GO:0034504 protein localization to nucleus
## GO:0031400 GO:0031400 negative regulation of protein modification process
## GO:1900180 GO:1900180 regulation of protein localization to nucleus
## GO:0051402 GO:0051402 neuron apoptotic process
## GO:0014037 GO:0014037 Schwann cell differentiation
## GO:1900182 GO:1900182 positive regulation of protein localization to nucleus
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0034504 12/55 311/18888 7.489550e-11 2.162982e-07 1.083225e-07
## GO:0031400 13/55 426/18888 2.000619e-10 2.888894e-07 1.446764e-07
## GO:1900180 9/55 144/18888 3.191962e-10 3.072795e-07 1.538862e-07
## GO:0051402 11/55 292/18888 6.535819e-10 4.718861e-07 2.363214e-07
## GO:0014037 6/55 49/18888 5.845827e-09 3.376550e-06 1.690982e-06
## GO:1900182 7/55 94/18888 1.006690e-08 4.845532e-06 2.426652e-06
## geneID
## GO:0034504 SQSTM1/PIK3R1/CDKN1A/CTNNA1/TFRC/PIK3R2/YWHAZ/YWHAE/AKT1/CDK1/PARK7/PARP1
## GO:0031400 SQSTM1/HSPA1A/CTNNB1/G6PD/CDKN1A/ADAR/PDCD4/ERRFI1/EIF4G1/YWHAE/YWHAB/AKT1/PARK7
## GO:1900180 PIK3R1/CTNNA1/TFRC/PIK3R2/YWHAZ/AKT1/CDK1/PARK7/PARP1
## GO:0051402 GAPDH/CTNNB1/COL6A1/ERBB3/G6PD/CCND1/AKT2/PARK7/BCL2L1/KDR/PARP1
## GO:0014037 COL6A1/ERBB3/NDRG1/AKT2/AKT1/CDK1
## GO:1900182 PIK3R1/TFRC/PIK3R2/AKT1/CDK1/PARK7/PARP1
## Count
## GO:0034504 12
## GO:0031400 13
## GO:1900180 9
## GO:0051402 11
## GO:0014037 6
## GO:1900182 7
## ID Description GeneRatio BgRatio pvalue
## GO:0005925 GO:0005925 focal adhesion 14/55 421/19894 5.761579e-12
## GO:0030055 GO:0030055 cell-substrate junction 14/55 431/19894 7.888574e-12
## GO:0042470 GO:0042470 melanosome 6/55 112/19894 6.443021e-07
## GO:0048770 GO:0048770 pigment granule 6/55 112/19894 6.443021e-07
## GO:0005912 GO:0005912 adherens junction 7/55 188/19894 8.325869e-07
## GO:0097125 GO:0097125 cyclin B1-CDK1 complex 2/55 2/19894 7.504712e-06
## p.adjust qvalue
## GO:0005925 9.979046e-10 5.106813e-10
## GO:0030055 9.979046e-10 5.106813e-10
## GO:0042470 4.075210e-05 2.085504e-05
## GO:0048770 4.075210e-05 2.085504e-05
## GO:0005912 4.212890e-05 2.155962e-05
## GO:0097125 3.164487e-04 1.619438e-04
## geneID
## GO:0005925 HSPA1A/TGM2/CTNNB1/CDH2/ANXA1/CTNNA1/ITGA2/PIK3R2/PXN/YWHAZ/MYH9/YWHAE/YWHAB/SHC1
## GO:0030055 HSPA1A/TGM2/CTNNB1/CDH2/ANXA1/CTNNA1/ITGA2/PIK3R2/PXN/YWHAZ/MYH9/YWHAE/YWHAB/SHC1
## GO:0042470 FASN/TFRC/YWHAZ/YWHAE/YWHAB/PRDX1
## GO:0048770 FASN/TFRC/YWHAZ/YWHAE/YWHAB/PRDX1
## GO:0005912 CTNNB1/CDH2/ANXA1/NDRG1/CTNNA1/MYH9/PARK7
## GO:0097125 CCNB1/CDK1
## Count
## GO:0005925 14
## GO:0030055 14
## GO:0042470 6
## GO:0048770 6
## GO:0005912 7
## GO:0097125 2
## ID Description GeneRatio
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 18/113
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 18/113
## GO:0019903 GO:0019903 protein phosphatase binding 13/113
## GO:0019902 GO:0019902 phosphatase binding 14/113
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 18/113
## GO:0106310 GO:0106310 protein serine kinase activity 16/113
## BgRatio pvalue p.adjust qvalue
## GO:0031625 305/18522 3.959025e-13 2.066611e-10 1.033514e-10
## GO:0044389 324/18522 1.103059e-12 2.878985e-10 1.439783e-10
## GO:0019903 142/18522 3.612479e-12 6.285714e-10 3.143491e-10
## GO:0019902 189/18522 9.279673e-12 1.210997e-09 6.056207e-10
## GO:0140297 478/18522 6.606275e-10 5.853864e-08 2.927522e-08
## GO:0106310 363/18522 6.728579e-10 5.853864e-08 2.927522e-08
## geneID
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/GSK3B/YWHAE/TUBA1B/BID/CHEK2/HSPA1A/CTNNB1/SQSTM1
## GO:0044389 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/GSK3B/YWHAE/TUBA1B/BID/CHEK2/HSPA1A/CTNNB1/SQSTM1
## GO:0019903 MET/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/STAT3/MAPT/MAPK8/PXN/YWHAE/CTNNB1/RPS6KB1
## GO:0019902 MET/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/STAT3/MAPT/MAPK8/PXN/YWHAE/CTNNB1/MAPK1/RPS6KB1
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/GSK3B/ARID1A/E2F1/YAP1/CTNNB1/EIF4E/TP53BP1
## GO:0106310 AKT2/RAF1/AKT1/ATM/CHEK1/GSK3B/PRKAA1/MAPK8/CHEK2/PRKCD/PIK3CA/PRKCA/MAPK1/RPS6KB1/NEK7/BRAF
## Count
## GO:0031625 18
## GO:0044389 18
## GO:0019903 13
## GO:0019902 14
## GO:0140297 18
## GO:0106310 16
## ID Description GeneRatio BgRatio
## GO:0051402 GO:0051402 neuron apoptotic process 24/113 292/18888
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 21/113 234/18888
## GO:0043434 GO:0043434 response to peptide hormone 26/113 438/18888
## GO:0044772 GO:0044772 mitotic cell cycle phase transition 26/113 451/18888
## GO:0018105 GO:0018105 peptidyl-serine phosphorylation 22/113 282/18888
## GO:0018209 GO:0018209 peptidyl-serine modification 22/113 294/18888
## pvalue p.adjust qvalue
## GO:0051402 8.546400e-21 3.519408e-17 1.635511e-17
## GO:0000082 4.664170e-19 8.492181e-16 3.946419e-16
## GO:0043434 6.186630e-19 8.492181e-16 3.946419e-16
## GO:0044772 1.275758e-18 1.064236e-15 4.945632e-16
## GO:0018105 1.292175e-18 1.064236e-15 4.945632e-16
## GO:0018209 3.165189e-18 2.172375e-15 1.009529e-15
## geneID
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/GSK3B/BID/AXL/MSH2/CASP3/CTNNB1/GAPDH/PIK3CA/DIABLO/BRAF
## GO:0000082 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/ATM/ARID1A/CCNE2/BID/CHEK2/E2F1/CCNE1/EIF4E/EIF4EBP1/EIF4G1/RPS6KB1
## GO:0043434 ERRFI1/AKT2/RB1/PTK2/CDKN1B/IRS1/PIK3R1/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PXN/PRKCD/CAV1/TFF1/PIK3CA/PRKCA/MAPK1/RPS6KB1/BRAF
## GO:0044772 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/ATM/CHEK1/ARID1A/CCNE2/BID/CHEK2/E2F1/CCNE1/EIF4E/EIF4EBP1/EIF4G1/FOXM1/RPS6KB1/RAB11A/ANLN/RAD50
## GO:0018105 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/ATM/GSK3B/PRKAA1/MAPK8/PRKCD/CAV1/EIF4G1/PRKCA/MAPK1/RET/RPS6KB1/TFRC/NEK7/RICTOR/BRAF
## GO:0018209 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/ATM/GSK3B/PRKAA1/MAPK8/PRKCD/CAV1/EIF4G1/PRKCA/MAPK1/RET/RPS6KB1/TFRC/NEK7/RICTOR/BRAF
## Count
## GO:0051402 24
## GO:0000082 21
## GO:0043434 26
## GO:0044772 26
## GO:0018105 22
## GO:0018209 22
## ID Description GeneRatio BgRatio
## GO:0005925 GO:0005925 focal adhesion 14/113 421/19894
## GO:0030055 GO:0030055 cell-substrate junction 14/113 431/19894
## GO:0000781 GO:0000781 chromosome, telomeric region 9/113 173/19894
## GO:0031968 GO:0031968 organelle outer membrane 10/113 248/19894
## GO:0019867 GO:0019867 outer membrane 10/113 250/19894
## GO:1902911 GO:1902911 protein kinase complex 8/113 150/19894
## pvalue p.adjust qvalue
## GO:0005925 1.189829e-07 2.662704e-05 1.593285e-05
## GO:0030055 1.584943e-07 2.662704e-05 1.593285e-05
## GO:0000781 6.351282e-07 7.113435e-05 4.256473e-05
## GO:0031968 1.525224e-06 1.101871e-04 6.593274e-05
## GO:0019867 1.639688e-06 1.101871e-04 6.593274e-05
## GO:1902911 2.271714e-06 1.272160e-04 7.612235e-05
## geneID
## GO:0005925 KRAS/MYH9/PTK2/EGFR/SHC1/YWHAZ/ITGA2/PXN/YWHAE/HSPA1A/CAV1/ANXA1/CTNNB1/MAPK1
## GO:0030055 KRAS/MYH9/PTK2/EGFR/SHC1/YWHAZ/ITGA2/PXN/YWHAE/HSPA1A/CAV1/ANXA1/CTNNB1/MAPK1
## GO:0000781 EZH2/ATM/PARP1/CHEK1/CHEK2/MSH2/ERCC1/TP53BP1/RAD50
## GO:0031968 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/BID/RPS6KB1
## GO:0019867 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/BID/RPS6KB1
## GO:1902911 RB1/CCND1/CDKN1A/IRS1/IGF1R/PRKAA1/CCNE2/CCNE1
## Count
## GO:0005925 14
## GO:0030055 14
## GO:0000781 9
## GO:0031968 10
## GO:0019867 10
## GO:1902911 8
## ID Description GeneRatio
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 19/125
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 19/125
## GO:0019903 GO:0019903 protein phosphatase binding 14/125
## GO:0019902 GO:0019902 phosphatase binding 15/125
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 20/125
## GO:0019207 GO:0019207 kinase regulator activity 16/125
## BgRatio pvalue p.adjust qvalue
## GO:0031625 305/18522 2.089422e-13 1.132467e-10 5.674431e-11
## GO:0044389 324/18522 6.138015e-13 1.353420e-10 6.781558e-11
## GO:0019903 142/18522 7.491256e-13 1.353420e-10 6.781558e-11
## GO:0019902 189/18522 2.633034e-12 3.567761e-10 1.787692e-10
## GO:0004674 427/18522 8.957830e-12 9.710287e-10 4.865516e-10
## GO:0019207 270/18522 4.016445e-11 3.296640e-09 1.651841e-09
## geneID
## GO:0031625 BCL2/ERBB3/HSPA1A/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SQSTM1
## GO:0044389 BCL2/ERBB3/HSPA1A/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SQSTM1
## GO:0019903 MET/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/RPS6KB1
## GO:0019902 MET/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/RPS6KB1
## GO:0004674 AKT2/EGFR/RAF1/AKT1/ATM/CDK1/CHEK1/MTOR/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/CHEK2/PRKCD/PIK3CA/RPS6KB1/NEK7/BRAF
## GO:0019207 ERBB3/CCND1/CDKN1A/CDKN1B/EGFR/PIK3R1/PIK3R2/AKT1/CCNE2/AKT1S1/YWHAB/CAV1/CASP3/CCNE1/PIK3CA/RICTOR
## Count
## GO:0031625 19
## GO:0044389 19
## GO:0019903 14
## GO:0019902 15
## GO:0004674 20
## GO:0019207 16
## ID Description GeneRatio BgRatio
## GO:0043434 GO:0043434 response to peptide hormone 29/125 438/18888
## GO:0051402 GO:0051402 neuron apoptotic process 25/125 292/18888
## GO:0062197 GO:0062197 cellular response to chemical stress 25/125 311/18888
## GO:0018105 GO:0018105 peptidyl-serine phosphorylation 24/125 282/18888
## GO:0018209 GO:0018209 peptidyl-serine modification 24/125 294/18888
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 22/125 234/18888
## pvalue p.adjust qvalue
## GO:0043434 4.350188e-21 1.387215e-17 6.214429e-18
## GO:0051402 6.247309e-21 1.387215e-17 6.214429e-18
## GO:0062197 2.926095e-20 4.331596e-17 1.940463e-17
## GO:0018105 4.716848e-20 5.236881e-17 2.346011e-17
## GO:0018209 1.256626e-19 1.116135e-16 5.000048e-17
## GO:0000082 2.257241e-19 1.670735e-16 7.484537e-17
## geneID
## GO:0043434 AKT2/ERRFI1/RB1/PTK2/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/MTOR/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/CAV1/TFF1/PIK3CA/RPS6KB1/BRAF
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/AKT1S1/BID/AXL/MSH2/CASP3/GAPDH/PIK3CA/DIABLO/BRAF
## GO:0062197 MET/G6PD/HSPA1A/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/ATM/PARP1/CDK1/MTOR/MAPT/PRKAA1/MAPK1/MAPK8/PXN/BECN1/PRKCD/AXL/CAV1/CASP3/PRDX1/PIK3CA
## GO:0018105 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/ATM/CDK1/MTOR/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/PRKCD/CAV1/EIF4G1/RET/RPS6KB1/TFRC/NEK7/RICTOR/BRAF
## GO:0018209 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/ATM/CDK1/MTOR/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/PRKCD/CAV1/EIF4G1/RET/RPS6KB1/TFRC/NEK7/RICTOR/BRAF
## GO:0000082 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/ATM/CDK1/ARID1A/CCNE2/BID/CHEK2/E2F1/CCNE1/EIF4E/EIF4EBP1/EIF4G1/RPS6KB1
## Count
## GO:0043434 29
## GO:0051402 25
## GO:0062197 25
## GO:0018105 24
## GO:0018209 24
## GO:0000082 22
## ID
## GO:0005925 GO:0005925
## GO:0000781 GO:0000781
## GO:0030055 GO:0030055
## GO:0031968 GO:0031968
## GO:0019867 GO:0019867
## GO:0061695 GO:0061695
## Description
## GO:0005925 focal adhesion
## GO:0000781 chromosome, telomeric region
## GO:0030055 cell-substrate junction
## GO:0031968 organelle outer membrane
## GO:0019867 outer membrane
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 16/125 421/19894 9.238717e-09 1.503633e-06 8.748084e-07
## GO:0000781 11/125 173/19894 1.230305e-08 1.503633e-06 8.748084e-07
## GO:0030055 16/125 431/19894 1.285157e-08 1.503633e-06 8.748084e-07
## GO:0031968 12/125 248/19894 5.479182e-08 4.200343e-06 2.443745e-06
## GO:0019867 12/125 250/19894 5.983395e-08 4.200343e-06 2.443745e-06
## GO:0061695 13/125 308/19894 7.400807e-08 4.329472e-06 2.518871e-06
## geneID
## GO:0005925 HSPA1A/KRAS/MYH9/PTK2/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/CAV1/ANXA1
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/CHEK2/MSH2/XRCC1/ERCC1/TP53BP1/RAD50
## GO:0030055 HSPA1A/KRAS/MYH9/PTK2/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/CAV1/ANXA1
## GO:0031968 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/MTOR/BECN1/BID/RPS6KB1
## GO:0019867 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/MTOR/BECN1/BID/RPS6KB1
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/CDK1/IGF1R/PRKAA1/BECN1/CCNE2/CCNE1/PIK3CA
## Count
## GO:0005925 16
## GO:0000781 11
## GO:0030055 16
## GO:0031968 12
## GO:0019867 12
## GO:0061695 13
## ID Description GeneRatio
## GO:0019903 GO:0019903 protein phosphatase binding 15/140
## GO:0019902 GO:0019902 phosphatase binding 16/140
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 19/140
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 19/140
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 22/140
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 20/140
## BgRatio pvalue p.adjust qvalue
## GO:0019903 142/18522 2.117064e-13 1.179204e-10 6.195196e-11
## GO:0019902 189/18522 1.032162e-12 2.874572e-10 1.510216e-10
## GO:0031625 305/18522 1.694282e-12 3.145717e-10 1.652668e-10
## GO:0044389 324/18522 4.904125e-12 6.828994e-10 3.587755e-10
## GO:0140297 478/18522 1.084954e-11 1.208638e-09 6.349834e-10
## GO:0004674 427/18522 7.537835e-11 6.997623e-09 3.676348e-09
## geneID
## GO:0019903 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/PTK2/RPS6KB1/CDH2
## GO:0019902 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/PTK2/RPS6KB1/CDH2
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/HSPA1A/SQSTM1
## GO:0044389 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/HSPA1A/SQSTM1
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/AR/CTNNB1/EIF4E/GSK3B/ARID1A/E2F1/YAP1/SMAD4/TP53BP1/GATA3/VHL
## GO:0004674 AKT2/EGFR/RAF1/AKT1/ATM/CDK1/CHEK1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/CHEK2/PRKCD/PIK3CA/RPS6KB1/NEK7/BRAF/ACVRL1
## Count
## GO:0019903 15
## GO:0019902 16
## GO:0031625 19
## GO:0044389 19
## GO:0140297 22
## GO:0004674 20
## ID Description GeneRatio
## GO:0051402 GO:0051402 neuron apoptotic process 27/140
## GO:0043434 GO:0043434 response to peptide hormone 30/140
## GO:0097191 GO:0097191 extrinsic apoptotic signaling pathway 22/140
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 22/140
## GO:0062197 GO:0062197 cellular response to chemical stress 24/140
## GO:0071375 GO:0071375 cellular response to peptide hormone stimulus 24/140
## BgRatio pvalue p.adjust qvalue
## GO:0051402 292/18888 4.474068e-22 2.074178e-18 9.593344e-19
## GO:0043434 438/18888 1.045762e-20 2.424075e-17 1.121166e-17
## GO:0097191 230/18888 1.996199e-18 3.084794e-15 1.426757e-15
## GO:0000082 234/18888 2.899894e-18 3.360977e-15 1.554496e-15
## GO:0062197 311/18888 7.448689e-18 5.755354e-15 2.661926e-15
## GO:0071375 311/18888 7.448689e-18 5.755354e-15 2.661926e-15
## geneID
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/DIABLO/AKT1S1/BID/AXL/MSH2/CASP3/GAPDH/PIK3CA/BRAF/COL6A1/GATA3
## GO:0043434 AKT2/ERRFI1/RB1/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/TFF1/PIK3CA/RPS6KB1/BRAF/COL6A1/TSC1
## GO:0097191 BCL2/ERBB3/PIK3R1/BCL2L11/RAF1/FOXO3/AKT1/BCL2L1/AR/CASP8/GSK3B/PEA15/DIABLO/BID/HSPA1A/CAV1/YAP1/SMAD4/SERPINE1/RET/RPS6KB1/CTNNA1
## GO:0000082 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/ATM/CDK1/EIF4E/EIF4G1/ARID1A/CCNE2/BID/CHEK2/E2F1/CCNE1/EIF4EBP1/RPS6KB1
## GO:0062197 MET/G6PD/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/ATM/PARP1/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/PXN/BECN1/PRKCD/HSPA1A/AXL/CAV1/CASP3/PRDX1/PIK3CA
## GO:0071375 AKT2/RB1/IRS1/PIK3R1/PIK3R2/RAF1/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/PIK3CA/RPS6KB1/COL6A1
## Count
## GO:0051402 27
## GO:0043434 30
## GO:0097191 22
## GO:0000082 22
## GO:0062197 24
## GO:0071375 24
## ID
## GO:0005925 GO:0005925
## GO:0030055 GO:0030055
## GO:0000781 GO:0000781
## GO:0061695 GO:0061695
## GO:1902911 GO:1902911
## GO:0044853 GO:0044853
## Description
## GO:0005925 focal adhesion
## GO:0030055 cell-substrate junction
## GO:0000781 chromosome, telomeric region
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GO:1902911 protein kinase complex
## GO:0044853 plasma membrane raft
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 19/140 421/19894 1.339410e-10 3.785075e-08 2.191359e-08
## GO:0030055 19/140 431/19894 1.992145e-10 3.785075e-08 2.191359e-08
## GO:0000781 12/140 173/19894 3.543075e-09 4.487895e-07 2.598255e-07
## GO:0061695 13/140 308/19894 2.819023e-07 2.678072e-05 1.550462e-05
## GO:1902911 9/140 150/19894 1.170938e-06 7.600626e-05 4.400362e-05
## GO:0044853 8/140 113/19894 1.352170e-06 7.600626e-05 4.400362e-05
## geneID
## GO:0005925 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/TGM2/CDH2/CTNNA1
## GO:0030055 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/TGM2/CDH2/CTNNA1
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/XRCC1/TP53BP1/RAD50
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/CDK1/IGF1R/PRKAA1/BECN1/CCNE2/CCNE1/PIK3CA
## GO:1902911 RB1/CCND1/CDKN1A/IRS1/CDK1/IGF1R/PRKAA1/CCNE2/CCNE1
## GO:0044853 IRS1/PTGS2/CTNNB1/IGF1R/MAPK1/CAV1/CDH2/CTNNA1
## Count
## GO:0005925 19
## GO:0030055 19
## GO:0000781 12
## GO:0061695 13
## GO:1902911 9
## GO:0044853 8
## ID Description GeneRatio
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 20/144
## GO:0019903 GO:0019903 protein phosphatase binding 15/144
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 20/144
## GO:0019902 GO:0019902 phosphatase binding 16/144
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 21/144
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 22/144
## BgRatio pvalue p.adjust qvalue
## GO:0031625 305/18522 2.778845e-13 9.174119e-11 4.777658e-11
## GO:0019903 142/18522 3.218989e-13 9.174119e-11 4.777658e-11
## GO:0044389 324/18522 8.549207e-13 1.624349e-10 8.459215e-11
## GO:0019902 189/18522 1.604252e-12 2.286059e-10 1.190524e-10
## GO:0004674 427/18522 1.681872e-11 1.832400e-09 9.542691e-10
## GO:0140297 478/18522 1.928842e-11 1.832400e-09 9.542691e-10
## geneID
## GO:0031625 BCL2/ERBB3/HSPA1A/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/SQSTM1
## GO:0019903 MET/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/RPS6KB1/CDH2
## GO:0044389 BCL2/ERBB3/HSPA1A/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/SQSTM1
## GO:0019902 MET/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/RPS6KB1/CDH2
## GO:0004674 AKT2/EGFR/RAF1/AKT1/ATM/CDK1/CHEK1/MTOR/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/CHEK2/PRKCD/PIK3CA/RPS6KB1/NEK7/BRAF/ACVRL1
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/VHL/STAT5A/STAT3/PARP1/AR/CTNNB1/EIF4E/GSK3B/ARID1A/E2F1/YAP1/SMAD4/TP53BP1/GATA3
## Count
## GO:0031625 20
## GO:0019903 15
## GO:0044389 20
## GO:0019902 16
## GO:0004674 21
## GO:0140297 22
## ID Description GeneRatio
## GO:0043434 GO:0043434 response to peptide hormone 32/144
## GO:0051402 GO:0051402 neuron apoptotic process 27/144
## GO:0071375 GO:0071375 cellular response to peptide hormone stimulus 26/144
## GO:1901653 GO:1901653 cellular response to peptide 27/144
## GO:0062197 GO:0062197 cellular response to chemical stress 25/144
## GO:0018105 GO:0018105 peptidyl-serine phosphorylation 24/144
## BgRatio pvalue p.adjust qvalue
## GO:0043434 438/18888 1.574587e-22 7.410008e-19 3.353042e-19
## GO:0051402 292/18888 9.814675e-22 2.309393e-18 1.045005e-18
## GO:0071375 311/18888 7.712721e-20 1.209869e-16 5.474679e-17
## GO:1901653 376/18888 7.213021e-19 8.486120e-16 3.839985e-16
## GO:0062197 311/18888 1.091608e-18 1.027421e-15 4.649100e-16
## GO:0018105 282/18888 1.523075e-18 1.194599e-15 5.405581e-16
## geneID
## GO:0043434 AKT2/ERRFI1/RB1/PTK2/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/MTOR/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/CAV1/TFF1/PIK3CA/RPS6KB1/BRAF/COL6A1/TSC1/XBP1
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/DIABLO/AKT1S1/BID/AXL/MSH2/CASP3/GAPDH/PIK3CA/BRAF/COL6A1/GATA3
## GO:0071375 AKT2/RB1/PTK2/IRS1/PIK3R1/PIK3R2/RAF1/SHC1/AKT1/STAT5A/STAT3/PARP1/MTOR/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/CAV1/PIK3CA/RPS6KB1/COL6A1/XBP1
## GO:1901653 AKT2/RB1/PTK2/IRS1/PIK3R1/PIK3R2/RAF1/SHC1/FOXO3/AKT1/STAT5A/STAT3/PARP1/MTOR/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/CAV1/PIK3CA/RPS6KB1/COL6A1/XBP1
## GO:0062197 MET/G6PD/HSPA1A/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/ATM/PARP1/CDK1/MTOR/MAPT/PRKAA1/MAPK1/MAPK8/PXN/BECN1/PRKCD/AXL/CAV1/CASP3/PRDX1/PIK3CA
## GO:0018105 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/ATM/CDK1/EIF4G1/MTOR/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/TFRC/PRKCD/CAV1/RET/RPS6KB1/NEK7/RICTOR/BRAF
## Count
## GO:0043434 32
## GO:0051402 27
## GO:0071375 26
## GO:1901653 27
## GO:0062197 25
## GO:0018105 24
## ID
## GO:0005925 GO:0005925
## GO:0030055 GO:0030055
## GO:0000781 GO:0000781
## GO:0031968 GO:0031968
## GO:0019867 GO:0019867
## GO:0061695 GO:0061695
## Description
## GO:0005925 focal adhesion
## GO:0030055 cell-substrate junction
## GO:0000781 chromosome, telomeric region
## GO:0031968 organelle outer membrane
## GO:0019867 outer membrane
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 19/144 421/19894 2.197096e-10 6.229460e-08 3.518984e-08
## GO:0030055 19/144 431/19894 3.261497e-10 6.229460e-08 3.518984e-08
## GO:0000781 12/144 173/19894 4.888511e-09 6.224704e-07 3.516297e-07
## GO:0031968 12/144 248/19894 2.615972e-07 2.178682e-05 1.230724e-05
## GO:0019867 12/144 250/19894 2.851678e-07 2.178682e-05 1.230724e-05
## GO:0061695 13/144 308/19894 3.911056e-07 2.490039e-05 1.406608e-05
## geneID
## GO:0005925 HSPA1A/KRAS/MYH9/PTK2/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/CAV1/ANXA1/TGM2/CDH2/CTNNA1
## GO:0030055 HSPA1A/KRAS/MYH9/PTK2/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/CAV1/ANXA1/TGM2/CDH2/CTNNA1
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/XRCC1/TP53BP1/RAD50
## GO:0031968 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/MTOR/BECN1/BID/RPS6KB1
## GO:0019867 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/MTOR/BECN1/BID/RPS6KB1
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/CDK1/IGF1R/PRKAA1/BECN1/CCNE2/CCNE1/PIK3CA
## Count
## GO:0005925 19
## GO:0030055 19
## GO:0000781 12
## GO:0031968 12
## GO:0019867 12
## GO:0061695 13
## ID Description GeneRatio
## GO:0032143 GO:0032143 single thymine insertion binding 2/18
## GO:0032137 GO:0032137 guanine/thymine mispair binding 2/18
## GO:0032142 GO:0032142 single guanine insertion binding 2/18
## GO:0032138 GO:0032138 single base insertion or deletion binding 2/18
## GO:0032135 GO:0032135 DNA insertion or deletion binding 2/18
## GO:0032405 GO:0032405 MutLalpha complex binding 2/18
## BgRatio pvalue p.adjust qvalue geneID Count
## GO:0032143 2/18522 8.920088e-07 0.0001497712 6.381227e-05 MSH6/MSH2 2
## GO:0032137 3/18522 2.674485e-06 0.0001497712 6.381227e-05 MSH6/MSH2 2
## GO:0032142 3/18522 2.674485e-06 0.0001497712 6.381227e-05 MSH6/MSH2 2
## GO:0032138 4/18522 5.345889e-06 0.0002245274 9.566328e-05 MSH6/MSH2 2
## GO:0032135 6/18522 1.334933e-05 0.0003737814 1.592552e-04 MSH6/MSH2 2
## GO:0032405 6/18522 1.334933e-05 0.0003737814 1.592552e-04 MSH6/MSH2 2
## ID
## GO:0002520 GO:0002520
## GO:0051053 GO:0051053
## GO:0035051 GO:0035051
## GO:0002562 GO:0002562
## GO:0016444 GO:0016444
## GO:0002200 GO:0002200
## Description
## GO:0002520 immune system development
## GO:0051053 negative regulation of DNA metabolic process
## GO:0035051 cardiocyte differentiation
## GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus
## GO:0016444 somatic cell DNA recombination
## GO:0002200 somatic diversification of immune receptors
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0002520 6/18 197/18888 1.995120e-08 3.034578e-05 1.516292e-05
## GO:0051053 5/18 142/18888 1.772137e-07 1.347710e-04 6.734120e-05
## GO:0035051 5/18 165/18888 3.741687e-07 1.548067e-04 7.735245e-05
## GO:0002562 4/18 70/18888 5.088977e-07 1.548067e-04 7.735245e-05
## GO:0016444 4/18 70/18888 5.088977e-07 1.548067e-04 7.735245e-05
## GO:0002200 4/18 76/18888 7.095469e-07 1.798701e-04 8.987595e-05
## geneID Count
## GO:0002520 ATM/MSH6/TFRC/RBM15/GATA3/MSH2 6
## GO:0051053 ATM/TTF1/MSH6/GATA3/MSH2 5
## GO:0035051 G6PD/PDCD4/MYH11/EGFR/TSC1 5
## GO:0002562 ATM/MSH6/TFRC/MSH2 4
## GO:0016444 ATM/MSH6/TFRC/MSH2 4
## GO:0002200 ATM/MSH6/TFRC/MSH2 4
## ID Description GeneRatio BgRatio pvalue
## GO:0032301 GO:0032301 MutSalpha complex 2/18 2/19894 7.732128e-07
## GO:0032300 GO:0032300 mismatch repair complex 2/18 11/19894 4.232193e-05
## GO:0042470 GO:0042470 melanosome 3/18 112/19894 1.332719e-04
## GO:0048770 GO:0048770 pigment granule 3/18 112/19894 1.332719e-04
## GO:0032302 GO:0032302 MutSbeta complex 1/18 2/19894 1.808818e-03
## GO:0070435 GO:0070435 Shc-EGFR complex 1/18 2/19894 1.808818e-03
## p.adjust qvalue geneID Count
## GO:0032301 6.804273e-05 3.906759e-05 MSH6/MSH2 2
## GO:0032300 1.862165e-03 1.069186e-03 MSH6/MSH2 2
## GO:0042470 2.931983e-03 1.683435e-03 FASN/MYH11/TFRC 3
## GO:0048770 2.931983e-03 1.683435e-03 FASN/MYH11/TFRC 3
## GO:0032302 2.593940e-02 1.489344e-02 MSH2 1
## GO:0070435 2.593940e-02 1.489344e-02 EGFR 1
## ID
## GO:0032143 GO:0032143
## GO:0032137 GO:0032137
## GO:0032142 GO:0032142
## GO:0032138 GO:0032138
## GO:0106017 GO:0106017
## GO:0032135 GO:0032135
## Description GeneRatio
## GO:0032143 single thymine insertion binding 2/25
## GO:0032137 guanine/thymine mispair binding 2/25
## GO:0032142 single guanine insertion binding 2/25
## GO:0032138 single base insertion or deletion binding 2/25
## GO:0106017 phosphatidylinositol-3,4-bisphosphate phosphatase activity 2/25
## GO:0032135 DNA insertion or deletion binding 2/25
## BgRatio pvalue p.adjust qvalue geneID Count
## GO:0032143 2/18522 1.749037e-06 0.0003477701 0.0001655610 MSH6/MSH2 2
## GO:0032137 3/18522 5.242766e-06 0.0003477701 0.0001655610 MSH6/MSH2 2
## GO:0032142 3/18522 5.242766e-06 0.0003477701 0.0001655610 MSH6/MSH2 2
## GO:0032138 4/18522 1.047685e-05 0.0004169787 0.0001985088 MSH6/MSH2 2
## GO:0106017 4/18522 1.047685e-05 0.0004169787 0.0001985088 PTEN/INPP4B 2
## GO:0032135 6/18522 2.614878e-05 0.0007433725 0.0003538933 MSH6/MSH2 2
## ID
## GO:0002520 GO:0002520
## GO:0002285 GO:0002285
## GO:0051053 GO:0051053
## GO:0002562 GO:0002562
## GO:0016444 GO:0016444
## GO:0002366 GO:0002366
## Description
## GO:0002520 immune system development
## GO:0002285 lymphocyte activation involved in immune response
## GO:0051053 negative regulation of DNA metabolic process
## GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus
## GO:0016444 somatic cell DNA recombination
## GO:0002366 leukocyte activation involved in immune response
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0002520 6/25 197/18888 1.791009e-07 0.0002446131 0.0001268547
## GO:0002285 6/25 212/18888 2.760870e-07 0.0002446131 0.0001268547
## GO:0051053 5/25 142/18888 1.053320e-06 0.0004780573 0.0002479173
## GO:0002562 4/25 70/18888 2.062995e-06 0.0004780573 0.0002479173
## GO:0016444 4/25 70/18888 2.062995e-06 0.0004780573 0.0002479173
## GO:0002366 6/25 301/18888 2.138290e-06 0.0004780573 0.0002479173
## geneID Count
## GO:0002520 TFRC/GATA3/MSH6/ATM/RBM15/MSH2 6
## GO:0002285 TFRC/GATA3/MSH6/MSH2/TSC1/XBP1 6
## GO:0051053 GATA3/MSH6/ATM/MSH2/TTF1 5
## GO:0002562 TFRC/MSH6/ATM/MSH2 4
## GO:0016444 TFRC/MSH6/ATM/MSH2 4
## GO:0002366 TFRC/GATA3/MSH6/MSH2/TSC1/XBP1 6
## ID Description GeneRatio BgRatio pvalue
## GO:0032301 GO:0032301 MutSalpha complex 2/25 2/19894 1.516104e-06
## GO:0042470 GO:0042470 melanosome 4/25 112/19894 1.099122e-05
## GO:0048770 GO:0048770 pigment granule 4/25 112/19894 1.099122e-05
## GO:0032300 GO:0032300 mismatch repair complex 2/25 11/19894 8.280912e-05
## GO:0032302 GO:0032302 MutSbeta complex 1/25 2/19894 2.511804e-03
## GO:0070435 GO:0070435 Shc-EGFR complex 1/25 2/19894 2.511804e-03
## p.adjust qvalue geneID Count
## GO:0032301 0.0001607070 9.415801e-05 MSH6/MSH2 2
## GO:0042470 0.0003883566 2.275376e-04 TFRC/FASN/MYH11/PRDX1 4
## GO:0048770 0.0003883566 2.275376e-04 TFRC/FASN/MYH11/PRDX1 4
## GO:0032300 0.0021944418 1.285721e-03 MSH6/MSH2 2
## GO:0032302 0.0391261253 2.292395e-02 MSH2 1
## GO:0070435 0.0391261253 2.292395e-02 EGFR 1
## ID Description GeneRatio
## GO:0045296 GO:0045296 cadherin binding 13/48
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 9/48
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 9/48
## GO:0019207 GO:0019207 kinase regulator activity 7/48
## GO:0045309 GO:0045309 protein phosphorylated amino acid binding 4/48
## GO:0019903 GO:0019903 protein phosphatase binding 5/48
## BgRatio pvalue p.adjust qvalue
## GO:0045296 333/18522 1.779006e-12 4.999007e-10 2.602967e-10
## GO:0031625 305/18522 7.553584e-08 1.061279e-05 5.526043e-06
## GO:0044389 324/18522 1.263639e-07 1.183608e-05 6.163010e-06
## GO:0019207 270/18522 5.717796e-06 4.016752e-04 2.091510e-04
## GO:0045309 59/18522 1.627145e-05 9.144552e-04 4.761539e-04
## GO:0019903 142/18522 3.241437e-05 1.518073e-03 7.904558e-04
## geneID
## GO:0045296 EEF2/HSPA1A/CTNNB1/CDH2/FASN/ANXA1/NDRG1/CTNNA1/MYH9/YWHAZ/YWHAB/KDR/NOTCH3
## GO:0031625 SQSTM1/HSPA1A/CTNNB1/ERBB3/CDKN1A/YWHAZ/PARP1/JUN/TUBA1B
## GO:0044389 SQSTM1/HSPA1A/CTNNB1/ERBB3/CDKN1A/YWHAZ/PARP1/JUN/TUBA1B
## GO:0019207 ERBB3/PIK3R1/CCND1/CDKN1A/AKT1/YWHAB/PIK3R2
## GO:0045309 PIK3R1/YWHAZ/YWHAB/PIK3R2
## GO:0019903 CTNNB1/CDH2/PIK3R1/PXN/PIK3R2
## Count
## GO:0045296 13
## GO:0031625 9
## GO:0044389 9
## GO:0019207 7
## GO:0045309 4
## GO:0019903 5
## ID Description
## GO:0045785 GO:0045785 positive regulation of cell adhesion
## GO:0071375 GO:0071375 cellular response to peptide hormone stimulus
## GO:0031400 GO:0031400 negative regulation of protein modification process
## GO:0043434 GO:0043434 response to peptide hormone
## GO:0030099 GO:0030099 myeloid cell differentiation
## GO:0048660 GO:0048660 regulation of smooth muscle cell proliferation
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0045785 12/48 485/18888 2.159693e-09 5.173694e-06 2.554297e-06
## GO:0071375 10/48 311/18888 4.767583e-09 5.173694e-06 2.554297e-06
## GO:0031400 11/48 426/18888 7.205508e-09 5.173694e-06 2.554297e-06
## GO:0043434 11/48 438/18888 9.603336e-09 5.173694e-06 2.554297e-06
## GO:0030099 11/48 439/18888 9.832181e-09 5.173694e-06 2.554297e-06
## GO:0048660 8/48 174/18888 1.216801e-08 5.335674e-06 2.634268e-06
## geneID
## GO:0045785 TGM2/IGFBP2/PRKCA/ANXA1/FN1/PREX1/AKT1/ITGA2/TFRC/KDR/PIK3R2/XBP1
## GO:0071375 COL6A1/PRKCA/PIK3R1/PXN/AKT2/AKT1/PARP1/STAT5A/PIK3R2/XBP1
## GO:0031400 SQSTM1/HSPA1A/CTNNB1/G6PD/PDCD4/ERRFI1/CDKN1A/AKT1/ADAR/YWHAB/EIF4G1
## GO:0043434 COL6A1/PRKCA/PIK3R1/PXN/ERRFI1/AKT2/AKT1/PARP1/STAT5A/PIK3R2/XBP1
## GO:0030099 HSPA1A/CTNNB1/FASN/PRKCA/G6PD/PIK3R1/MYH9/ADAR/TFRC/PARP1/STAT5A
## GO:0048660 CTNNB1/PDCD4/PIK3R1/CDKN1A/AKT1/ITGA2/JUN/NOTCH3
## Count
## GO:0045785 12
## GO:0071375 10
## GO:0031400 11
## GO:0043434 11
## GO:0030099 11
## GO:0048660 8
## ID Description GeneRatio BgRatio
## GO:0005925 GO:0005925 focal adhesion 12/48 421/19894
## GO:0030055 GO:0030055 cell-substrate junction 12/48 431/19894
## GO:0005912 GO:0005912 adherens junction 6/48 188/19894
## GO:0016342 GO:0016342 catenin complex 3/48 31/19894
## GO:0019898 GO:0019898 extrinsic component of membrane 5/48 177/19894
## GO:0031252 GO:0031252 cell leading edge 7/48 426/19894
## pvalue p.adjust qvalue
## GO:0005925 2.416166e-10 3.665730e-08 1.812906e-08
## GO:0030055 3.160112e-10 3.665730e-08 1.812906e-08
## GO:0005912 5.801947e-06 4.486839e-04 2.218990e-04
## GO:0016342 5.650618e-05 2.444049e-03 1.208718e-03
## GO:0019898 6.617899e-05 2.444049e-03 1.208718e-03
## GO:0031252 6.780532e-05 2.444049e-03 1.208718e-03
## geneID
## GO:0005925 TGM2/HSPA1A/CTNNB1/CDH2/ANXA1/CTNNA1/MYH9/PXN/YWHAZ/ITGA2/YWHAB/PIK3R2
## GO:0030055 TGM2/HSPA1A/CTNNB1/CDH2/ANXA1/CTNNA1/MYH9/PXN/YWHAZ/ITGA2/YWHAB/PIK3R2
## GO:0005912 CTNNB1/CDH2/ANXA1/NDRG1/CTNNA1/MYH9
## GO:0016342 CTNNB1/CDH2/CTNNA1
## GO:0019898 CTNNB1/CDH2/CTNNA1/PIK3R1/PIK3R2
## GO:0031252 CTNNB1/CDH2/CTNNA1/MYH9/PXN/AKT2/AKT1
## Count
## GO:0005925 12
## GO:0030055 12
## GO:0005912 6
## GO:0016342 3
## GO:0019898 5
## GO:0031252 7
## ID Description GeneRatio
## GO:0045296 GO:0045296 cadherin binding 10/45
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 8/45
## GO:0019903 GO:0019903 protein phosphatase binding 6/45
## GO:0019902 GO:0019902 phosphatase binding 6/45
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 7/45
## GO:0045309 GO:0045309 protein phosphorylated amino acid binding 4/45
## BgRatio pvalue p.adjust qvalue
## GO:0045296 333/18522 5.630025e-09 1.649597e-06 7.763508e-07
## GO:0044389 324/18522 9.868523e-07 1.135853e-04 5.345669e-05
## GO:0019903 142/18522 1.162989e-06 1.135853e-04 5.345669e-05
## GO:0019902 189/18522 6.100384e-06 4.468531e-04 2.103027e-04
## GO:0031625 305/18522 8.133231e-06 4.766073e-04 2.243060e-04
## GO:0045309 59/18522 1.254850e-05 6.127850e-04 2.883953e-04
## geneID Count
## GO:0045296 EEF2/HSPA1A/CTNNB1/CDH2/FASN/NDRG1/YWHAE/PARK7/MYH9/ANXA1 10
## GO:0044389 HSPA1A/CTNNB1/SQSTM1/TUBA1B/CDKN1A/YWHAE/JUN/CCNB1 8
## GO:0019903 CTNNB1/CDH2/PIK3R2/YWHAE/PXN/PIK3R1 6
## GO:0019902 CTNNB1/CDH2/PIK3R2/YWHAE/PXN/PIK3R1 6
## GO:0031625 HSPA1A/CTNNB1/SQSTM1/TUBA1B/CDKN1A/YWHAE/JUN 7
## GO:0045309 PIK3R2/SHC1/YWHAE/PIK3R1 4
## ID Description
## GO:0031400 GO:0031400 negative regulation of protein modification process
## GO:0034504 GO:0034504 protein localization to nucleus
## GO:0030099 GO:0030099 myeloid cell differentiation
## GO:1900182 GO:1900182 positive regulation of protein localization to nucleus
## GO:1903829 GO:1903829 positive regulation of protein localization
## GO:0048009 GO:0048009 insulin-like growth factor receptor signaling pathway
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0031400 12/45 426/18888 2.179360e-10 5.760047e-07 2.943282e-07
## GO:0034504 9/45 311/18888 4.173133e-08 5.514796e-05 2.817963e-05
## GO:0030099 10/45 439/18888 6.400455e-08 5.638801e-05 2.881328e-05
## GO:1900182 6/45 94/18888 9.004280e-08 5.949578e-05 3.040129e-05
## GO:1903829 10/45 483/18888 1.557480e-07 6.364657e-05 3.252227e-05
## GO:0048009 5/45 53/18888 1.608698e-07 6.364657e-05 3.252227e-05
## geneID
## GO:0031400 HSPA1A/CTNNB1/SQSTM1/ADAR/CDKN1A/AKT1/YWHAE/EIF4G1/G6PD/PARK7/PRKCD/PDCD4
## GO:0034504 SQSTM1/TFRC/CDKN1A/PIK3R2/AKT1/YWHAE/PIK3R1/PARK7/PRKCD
## GO:0030099 HSPA1A/CTNNB1/ADAR/TFRC/FASN/PRKCA/PIK3R1/G6PD/MYH9/BAP1
## GO:1900182 TFRC/PIK3R2/AKT1/PIK3R1/PARK7/PRKCD
## GO:1903829 SQSTM1/TFRC/PIK3R2/AKT1/YWHAE/EIF4G1/PIK3R1/PARK7/PRKCD/BAP1
## GO:0048009 COL6A1/SHC1/AKT1/IGFBP2/PIK3R1
## Count
## GO:0031400 12
## GO:0034504 9
## GO:0030099 10
## GO:1900182 6
## GO:1903829 10
## GO:0048009 5
## ID Description GeneRatio
## GO:0005925 GO:0005925 focal adhesion 11/45
## GO:0030055 GO:0030055 cell-substrate junction 11/45
## GO:0005912 GO:0005912 adherens junction 6/45
## GO:0062023 GO:0062023 collagen-containing extracellular matrix 7/45
## GO:0016235 GO:0016235 aggresome 3/45
## GO:0005916 GO:0005916 fascia adherens 2/45
## BgRatio pvalue p.adjust qvalue
## GO:0005925 421/19894 1.779464e-09 2.683762e-07 1.364625e-07
## GO:0030055 431/19894 2.274374e-09 2.683762e-07 1.364625e-07
## GO:0005912 188/19894 3.942557e-06 3.101478e-04 1.577023e-04
## GO:0062023 428/19894 4.549194e-05 2.684024e-03 1.364758e-03
## GO:0016235 35/19894 6.728824e-05 3.176005e-03 1.614918e-03
## GO:0005916 9/19894 1.783048e-04 5.259990e-03 2.674571e-03
## geneID Count
## GO:0005925 HSPA1A/CTNNB1/CDH2/PIK3R2/SHC1/ITGA2/YWHAE/TGM2/PXN/MYH9/ANXA1 11
## GO:0030055 HSPA1A/CTNNB1/CDH2/PIK3R2/SHC1/ITGA2/YWHAE/TGM2/PXN/MYH9/ANXA1 11
## GO:0005912 CTNNB1/CDH2/NDRG1/PARK7/MYH9/ANXA1 6
## GO:0062023 FN1/CDH2/SERPINE1/COL6A1/TGM2/ANXA1/ANXA7 7
## GO:0016235 EEF2/HSPA1A/SQSTM1 3
## GO:0005916 CTNNB1/CDH2 2
## ID Description GeneRatio
## GO:0045296 GO:0045296 cadherin binding 14/53
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 10/53
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 10/53
## GO:0019903 GO:0019903 protein phosphatase binding 7/53
## GO:0045309 GO:0045309 protein phosphorylated amino acid binding 5/53
## GO:0019902 GO:0019902 phosphatase binding 7/53
## BgRatio pvalue p.adjust qvalue
## GO:0045296 333/18522 3.587395e-13 1.040345e-10 5.324449e-11
## GO:0031625 305/18522 1.319362e-08 1.913075e-06 9.791055e-07
## GO:0044389 324/18522 2.339069e-08 2.261100e-06 1.157224e-06
## GO:0019903 142/18522 1.540591e-07 1.116928e-05 5.716403e-06
## GO:0045309 59/18522 7.041119e-07 4.083849e-05 2.090101e-05
## GO:0019902 189/18522 1.068580e-06 5.164805e-05 2.643330e-05
## geneID
## GO:0045296 HSPA1A/EEF2/CDH2/FASN/CTNNB1/ANXA1/NDRG1/CTNNA1/MYH9/YWHAZ/KDR/YWHAE/NOTCH3/YWHAB
## GO:0031625 SQSTM1/HSPA1A/ERBB3/CTNNB1/YWHAZ/PARP1/CDKN1A/JUN/TUBA1B/YWHAE
## GO:0044389 SQSTM1/HSPA1A/ERBB3/CTNNB1/YWHAZ/PARP1/CDKN1A/JUN/TUBA1B/YWHAE
## GO:0019903 CDH2/CTNNB1/PIK3R1/PXN/PIK3R2/YWHAE/MET
## GO:0045309 PIK3R1/YWHAZ/PIK3R2/YWHAE/YWHAB
## GO:0019902 CDH2/CTNNB1/PIK3R1/PXN/PIK3R2/YWHAE/MET
## Count
## GO:0045296 14
## GO:0031625 10
## GO:0044389 10
## GO:0019903 7
## GO:0045309 5
## GO:0019902 7
## ID Description
## GO:0001667 GO:0001667 ameboidal-type cell migration
## GO:0010634 GO:0010634 positive regulation of epithelial cell migration
## GO:0031400 GO:0031400 negative regulation of protein modification process
## GO:0030099 GO:0030099 myeloid cell differentiation
## GO:0010631 GO:0010631 epithelial cell migration
## GO:0090132 GO:0090132 epithelium migration
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0001667 13/53 498/18888 8.183022e-10 1.536984e-06 7.851378e-07
## GO:0010634 9/53 177/18888 1.413038e-09 1.536984e-06 7.851378e-07
## GO:0031400 12/53 426/18888 1.717301e-09 1.536984e-06 7.851378e-07
## GO:0030099 12/53 439/18888 2.410056e-09 1.617750e-06 8.263955e-07
## GO:0010631 11/53 375/18888 5.896643e-09 2.195806e-06 1.121684e-06
## GO:0090132 11/53 378/18888 6.404612e-09 2.195806e-06 1.121684e-06
## geneID
## GO:0001667 CDH2/PRKCA/ANXA1/FN1/MYH9/PXN/KDR/AKT1/ITGA2/RAB11A/ETS1/STAT5A/MET
## GO:0010634 PRKCA/ANXA1/KDR/AKT1/ITGA2/RAB11A/ETS1/STAT5A/MET
## GO:0031400 SQSTM1/HSPA1A/CTNNB1/PDCD4/G6PD/ERRFI1/CDKN1A/EIF4G1/AKT1/YWHAE/ADAR/YWHAB
## GO:0030099 HSPA1A/PRKCA/FASN/CTNNB1/G6PD/PIK3R1/MYH9/TFRC/PARP1/ETS1/STAT5A/ADAR
## GO:0010631 PRKCA/ANXA1/MYH9/PXN/KDR/AKT1/ITGA2/RAB11A/ETS1/STAT5A/MET
## GO:0090132 PRKCA/ANXA1/MYH9/PXN/KDR/AKT1/ITGA2/RAB11A/ETS1/STAT5A/MET
## Count
## GO:0001667 13
## GO:0010634 9
## GO:0031400 12
## GO:0030099 12
## GO:0010631 11
## GO:0090132 11
## ID Description GeneRatio BgRatio pvalue
## GO:0005925 GO:0005925 focal adhesion 13/53 421/19894 5.544249e-11
## GO:0030055 GO:0030055 cell-substrate junction 13/53 431/19894 7.413751e-11
## GO:0005912 GO:0005912 adherens junction 6/53 188/19894 1.043748e-05
## GO:0042470 GO:0042470 melanosome 5/53 112/19894 1.196057e-05
## GO:0048770 GO:0048770 pigment granule 5/53 112/19894 1.196057e-05
## GO:0045178 GO:0045178 basal part of cell 7/53 305/19894 1.565599e-05
## p.adjust qvalue
## GO:0005925 8.933570e-09 4.643349e-09
## GO:0030055 8.933570e-09 4.643349e-09
## GO:0005912 5.764993e-04 2.996437e-04
## GO:0042470 5.764993e-04 2.996437e-04
## GO:0048770 5.764993e-04 2.996437e-04
## GO:0045178 6.288488e-04 3.268530e-04
## geneID
## GO:0005925 TGM2/HSPA1A/CDH2/CTNNB1/ANXA1/CTNNA1/MYH9/YWHAZ/PXN/PIK3R2/ITGA2/YWHAE/YWHAB
## GO:0030055 TGM2/HSPA1A/CDH2/CTNNB1/ANXA1/CTNNA1/MYH9/YWHAZ/PXN/PIK3R2/ITGA2/YWHAE/YWHAB
## GO:0005912 CDH2/CTNNB1/ANXA1/NDRG1/CTNNA1/MYH9
## GO:0042470 FASN/YWHAZ/TFRC/YWHAE/YWHAB
## GO:0048770 FASN/YWHAZ/TFRC/YWHAE/YWHAB
## GO:0045178 ERBB3/CDH2/CTNNB1/ANXA1/TFRC/ITGA2/MET
## Count
## GO:0005925 13
## GO:0030055 13
## GO:0005912 6
## GO:0042470 5
## GO:0048770 5
## GO:0045178 7
## ID Description GeneRatio
## GO:0045296 GO:0045296 cadherin binding 12/49
## GO:0045309 GO:0045309 protein phosphorylated amino acid binding 5/49
## GO:0019902 GO:0019902 phosphatase binding 7/49
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 8/49
## GO:0019903 GO:0019903 protein phosphatase binding 6/49
## GO:0030971 GO:0030971 receptor tyrosine kinase binding 5/49
## BgRatio pvalue p.adjust qvalue
## GO:0045296 333/18522 4.758727e-11 1.489481e-08 6.762401e-09
## GO:0045309 59/18522 4.724478e-07 6.430525e-05 2.919525e-05
## GO:0019902 189/18522 6.163443e-07 6.430525e-05 2.919525e-05
## GO:0044389 324/18522 1.942916e-06 1.207549e-04 5.482397e-05
## GO:0019903 142/18522 1.947041e-06 1.207549e-04 5.482397e-05
## GO:0030971 81/18522 2.314790e-06 1.207549e-04 5.482397e-05
## geneID
## GO:0045296 HSPA1A/EEF2/CTNNB1/CDH2/FASN/YWHAE/NDRG1/ANXA1/MYH9/PARK7/ANLN/CTNNA1
## GO:0045309 SHC1/PIK3R2/YWHAE/MAPK1/PIK3R1
## GO:0019902 CTNNB1/CDH2/PIK3R2/YWHAE/PXN/MAPK1/PIK3R1
## GO:0044389 SQSTM1/HSPA1A/CTNNB1/TUBA1B/CDKN1A/YWHAE/JUN/CCNB1
## GO:0019903 CTNNB1/CDH2/PIK3R2/YWHAE/PXN/PIK3R1
## GO:0030971 SQSTM1/SHC1/PIK3R2/PCNA/PIK3R1
## Count
## GO:0045296 12
## GO:0045309 5
## GO:0019902 7
## GO:0044389 8
## GO:0019903 6
## GO:0030971 5
## ID Description
## GO:0034504 GO:0034504 protein localization to nucleus
## GO:0031400 GO:0031400 negative regulation of protein modification process
## GO:0034599 GO:0034599 cellular response to oxidative stress
## GO:0032075 GO:0032075 positive regulation of nuclease activity
## GO:0000302 GO:0000302 response to reactive oxygen species
## GO:1900180 GO:1900180 regulation of protein localization to nucleus
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0034504 11/49 311/18888 3.375982e-10 6.119571e-07 3.087600e-07
## GO:0031400 12/49 426/18888 6.443749e-10 6.119571e-07 3.087600e-07
## GO:0034599 10/49 248/18888 6.661362e-10 6.119571e-07 3.087600e-07
## GO:0032075 4/49 7/18888 1.390814e-09 9.582708e-07 4.834909e-07
## GO:0000302 9/49 203/18888 2.269570e-09 1.250987e-06 6.311792e-07
## GO:1900180 8/49 144/18888 3.250569e-09 1.304111e-06 6.579826e-07
## geneID
## GO:0034504 SQSTM1/TFRC/CDKN1A/PIK3R2/YWHAE/AKT1/PRKCD/PARK7/PIK3R1/CDK1/CTNNA1
## GO:0031400 SQSTM1/HSPA1A/CTNNB1/ADAR/CDKN1A/YWHAE/EIF4G1/AKT1/PDCD4/G6PD/PRKCD/PARK7
## GO:0034599 HSPA1A/PXN/AKT1/JUN/PCNA/G6PD/PRKCD/MAPK1/PARK7/CDK1
## GO:0032075 HSPA1A/AKT1/PCNA/PRKCD
## GO:0000302 COL6A1/PXN/AKT1/JUN/PCNA/PRKCD/MAPK1/PARK7/CDK1
## GO:1900180 TFRC/PIK3R2/AKT1/PRKCD/PARK7/PIK3R1/CDK1/CTNNA1
## Count
## GO:0034504 11
## GO:0031400 12
## GO:0034599 10
## GO:0032075 4
## GO:0000302 9
## GO:1900180 8
## ID Description
## GO:0005925 GO:0005925 focal adhesion
## GO:0030055 GO:0030055 cell-substrate junction
## GO:0000307 GO:0000307 cyclin-dependent protein kinase holoenzyme complex
## GO:0005912 GO:0005912 adherens junction
## GO:0070557 GO:0070557 PCNA-p21 complex
## GO:0097125 GO:0097125 cyclin B1-CDK1 complex
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 13/49 421/19894 1.868462e-11 3.166591e-09 1.620515e-09
## GO:0030055 13/49 431/19894 2.503234e-11 3.166591e-09 1.620515e-09
## GO:0000307 5/49 56/19894 2.554437e-07 2.154242e-05 1.102441e-05
## GO:0005912 7/49 188/19894 3.696901e-07 2.338290e-05 1.196628e-05
## GO:0070557 2/49 2/19894 5.943126e-06 2.506018e-04 1.282464e-04
## GO:0097125 2/49 2/19894 5.943126e-06 2.506018e-04 1.282464e-04
## geneID
## GO:0005925 HSPA1A/CTNNB1/CDH2/SHC1/PIK3R2/ITGA2/YWHAE/TGM2/PXN/ANXA1/MYH9/MAPK1/CTNNA1
## GO:0030055 HSPA1A/CTNNB1/CDH2/SHC1/PIK3R2/ITGA2/YWHAE/TGM2/PXN/ANXA1/MYH9/MAPK1/CTNNA1
## GO:0000307 CCND1/CDKN1A/PCNA/CCNB1/CDK1
## GO:0005912 CTNNB1/CDH2/NDRG1/ANXA1/MYH9/PARK7/CTNNA1
## GO:0070557 CDKN1A/PCNA
## GO:0097125 CCNB1/CDK1
## Count
## GO:0005925 13
## GO:0030055 13
## GO:0000307 5
## GO:0005912 7
## GO:0070557 2
## GO:0097125 2
## ID Description GeneRatio
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 20/130
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 20/130
## GO:0019903 GO:0019903 protein phosphatase binding 14/130
## GO:0019902 GO:0019902 phosphatase binding 15/130
## GO:0019207 GO:0019207 kinase regulator activity 16/130
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 20/130
## BgRatio pvalue p.adjust qvalue
## GO:0031625 305/18522 3.777491e-14 2.047400e-11 1.041792e-11
## GO:0044389 324/18522 1.178373e-13 3.193392e-11 1.624915e-11
## GO:0019903 142/18522 1.294257e-12 2.338291e-10 1.189808e-10
## GO:0019902 189/18522 4.697829e-12 6.365558e-10 3.239029e-10
## GO:0019207 270/18522 7.338435e-11 7.954864e-09 4.047726e-09
## GO:0140297 478/18522 1.408162e-10 1.168562e-08 5.946070e-09
## geneID
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/HSPA1A/SQSTM1
## GO:0044389 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/HSPA1A/SQSTM1
## GO:0019903 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/PTK2/RPS6KB1
## GO:0019902 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/PTK2/RPS6KB1
## GO:0019207 ERBB3/CCND1/CDKN1A/CDKN1B/EGFR/PIK3R1/PIK3R2/AKT1/CCNE2/AKT1S1/YWHAB/CAV1/CASP3/CCNE1/PIK3CA/RICTOR
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/AR/CTNNB1/EIF4E/GSK3B/ARID1A/E2F1/YAP1/SMAD4/TP53BP1
## Count
## GO:0031625 20
## GO:0044389 20
## GO:0019903 14
## GO:0019902 15
## GO:0019207 16
## GO:0140297 20
## ID Description GeneRatio BgRatio
## GO:0051402 GO:0051402 neuron apoptotic process 25/130 292/18888
## GO:0043434 GO:0043434 response to peptide hormone 28/130 438/18888
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 22/130 234/18888
## GO:0062197 GO:0062197 cellular response to chemical stress 24/130 311/18888
## GO:0018105 GO:0018105 peptidyl-serine phosphorylation 23/130 282/18888
## GO:0010038 GO:0010038 response to metal ion 25/130 360/18888
## pvalue p.adjust qvalue
## GO:0051402 1.728946e-20 7.781986e-17 3.534330e-17
## GO:0043434 1.805625e-19 4.063558e-16 1.845539e-16
## GO:0000082 5.490606e-19 8.237740e-16 3.741318e-16
## GO:0062197 1.227584e-18 1.381339e-15 6.273599e-16
## GO:0018105 2.004592e-18 1.804533e-15 8.195614e-16
## GO:0010038 2.748137e-18 2.061560e-15 9.362950e-16
## geneID
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/DIABLO/AKT1S1/BID/AXL/MSH2/CASP3/GAPDH/PIK3CA/BRAF
## GO:0043434 AKT2/ERRFI1/RB1/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/TFF1/PIK3CA/RPS6KB1/BRAF
## GO:0000082 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/ATM/CDK1/EIF4E/EIF4G1/ARID1A/CCNE2/BID/CHEK2/E2F1/CCNE1/EIF4EBP1/RPS6KB1
## GO:0062197 MET/G6PD/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/ATM/PARP1/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/PXN/BECN1/PRKCD/HSPA1A/AXL/CAV1/CASP3/PRDX1/PIK3CA
## GO:0018105 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/ATM/CDK1/EIF4G1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/TFRC/PRKCD/CAV1/RET/RPS6KB1/NEK7/RICTOR/BRAF
## GO:0010038 G6PD/BCL2/KIT/CDKN1B/EGFR/JUN/PTGS2/AKT1/PARP1/CASP8/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/TFRC/BECN1/NDRG1/EEF2K/ERCC1/CAV1/CASP3/TFF1/NEK7/BRAF
## Count
## GO:0051402 25
## GO:0043434 28
## GO:0000082 22
## GO:0062197 24
## GO:0018105 23
## GO:0010038 25
## ID
## GO:0000781 GO:0000781
## GO:0005925 GO:0005925
## GO:0030055 GO:0030055
## GO:0061695 GO:0061695
## GO:1902911 GO:1902911
## GO:0031968 GO:0031968
## Description
## GO:0000781 chromosome, telomeric region
## GO:0005925 focal adhesion
## GO:0030055 cell-substrate junction
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GO:1902911 protein kinase complex
## GO:0031968 organelle outer membrane
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0000781 12/130 173/19894 1.510211e-09 5.512271e-07 3.322465e-07
## GO:0005925 16/130 421/19894 1.635708e-08 2.761768e-06 1.664628e-06
## GO:0030055 16/130 431/19894 2.269947e-08 2.761768e-06 1.664628e-06
## GO:0061695 13/130 308/19894 1.179933e-07 1.076689e-05 6.489630e-06
## GO:1902911 9/130 150/19894 6.275122e-07 4.025720e-05 2.426461e-05
## GO:0031968 11/130 248/19894 7.132908e-07 4.025720e-05 2.426461e-05
## geneID
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/XRCC1/TP53BP1/RAD50
## GO:0005925 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1
## GO:0030055 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/CDK1/IGF1R/PRKAA1/BECN1/CCNE2/CCNE1/PIK3CA
## GO:1902911 RB1/CCND1/CDKN1A/IRS1/CDK1/IGF1R/PRKAA1/CCNE2/CCNE1
## GO:0031968 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/BECN1/BID/RPS6KB1
## Count
## GO:0000781 12
## GO:0005925 16
## GO:0030055 16
## GO:0061695 13
## GO:1902911 9
## GO:0031968 11
## ID Description GeneRatio
## GO:0019902 GO:0019902 phosphatase binding 16/125
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 22/125
## GO:0019207 GO:0019207 kinase regulator activity 17/125
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 20/125
## GO:0019903 GO:0019903 protein phosphatase binding 13/125
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 17/125
## BgRatio pvalue p.adjust qvalue
## GO:0019902 189/18522 1.719680e-13 9.183092e-11 4.670289e-11
## GO:0140297 478/18522 1.026637e-12 2.741120e-10 1.394064e-10
## GO:0019207 270/18522 3.581531e-12 6.375126e-10 3.242228e-10
## GO:0004674 427/18522 8.957830e-12 1.195870e-09 6.081895e-10
## GO:0019903 142/18522 1.332590e-11 1.423206e-09 7.238070e-10
## GO:0031625 305/18522 2.485038e-11 2.211684e-09 1.124807e-09
## geneID
## GO:0019902 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/MAPT/MAPK1/MAPK8/PXN/YWHAE/PTK2/SMAD3/MAPK3/RPS6KB1
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/AR/EIF4E/GSK3B/ARID1A/E2F1/CDKN2A/YAP1/SMAD3/SMAD4/MAPK3/TP53BP1
## GO:0019207 ERBB3/CCND1/CDKN1A/CDKN1B/EGFR/PIK3R1/PIK3R2/AKT1/CCNE2/AKT1S1/YWHAB/CDKN2A/CAV1/CASP3/CCNE1/PIK3CA/RICTOR
## GO:0004674 AKT2/EGFR/RAF1/AKT1/CHEK1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/CHEK2/PRKCD/MAPK9/CDK1/PIK3CA/MAPK3/RPS6KB1/NEK7/BRAF
## GO:0019903 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/MAPT/MAPK8/PXN/YWHAE/PTK2/RPS6KB1
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/GSK3B/YWHAE/TUBA1B/BID/CHEK2/HSPA1A/SMAD3/SQSTM1
## Count
## GO:0019902 16
## GO:0140297 22
## GO:0019207 17
## GO:0004674 20
## GO:0019903 13
## GO:0031625 17
## ID Description GeneRatio
## GO:0043434 GO:0043434 response to peptide hormone 30/125
## GO:0010038 GO:0010038 response to metal ion 26/125
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 22/125
## GO:0071375 GO:0071375 cellular response to peptide hormone stimulus 24/125
## GO:0018105 GO:0018105 peptidyl-serine phosphorylation 23/125
## GO:0044772 GO:0044772 mitotic cell cycle phase transition 27/125
## BgRatio pvalue p.adjust qvalue
## GO:0043434 438/18888 3.091366e-22 1.284153e-18 6.130667e-19
## GO:0010038 360/18888 7.039858e-20 1.462178e-16 6.980575e-17
## GO:0000082 234/18888 2.257241e-19 3.125527e-16 1.492155e-16
## GO:0071375 311/18888 4.678801e-19 4.858935e-16 2.319700e-16
## GO:0018105 282/18888 7.956045e-19 6.609882e-16 3.155619e-16
## GO:0044772 451/18888 1.580125e-18 1.031375e-15 4.923882e-16
## geneID
## GO:0043434 ERRFI1/AKT2/RB1/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/TFF1/SMAD3/PIK3CA/MAPK3/RPS6KB1/BRAF
## GO:0010038 G6PD/BCL2/KIT/CDKN1B/EGFR/JUN/PTGS2/AKT1/PARP1/MAPT/PRKAA1/MAPK1/MAPK8/NDRG1/EEF2K/ERCC1/CASP9/CAV1/CASP3/MAPK9/TFF1/CDK1/MAPK3/TFRC/NEK7/BRAF
## GO:0000082 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/EIF4E/EIF4G1/ARID1A/CCNE2/BID/CHEK2/E2F1/CDKN2A/CCNE1/CDK1/EIF4EBP1/RPS6KB1
## GO:0071375 AKT2/RB1/IRS1/PIK3R1/PIK3R2/RAF1/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/PIK3CA/MAPK3/RPS6KB1
## GO:0018105 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/EIF4G1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/PRKCD/CAV1/MAPK9/CDK1/RET/RPS6KB1/TFRC/NEK7/RICTOR/BRAF
## GO:0044772 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/CHEK1/EIF4E/EIF4G1/ARID1A/CCNE2/BID/CHEK2/E2F1/CDKN2A/CCNE1/CDK1/EIF4EBP1/FOXM1/RPS6KB1/RAB11A/ANLN/RAD50
## Count
## GO:0043434 30
## GO:0010038 26
## GO:0000082 22
## GO:0071375 24
## GO:0018105 23
## GO:0044772 27
## ID
## GO:0005925 GO:0005925
## GO:0000781 GO:0000781
## GO:0030055 GO:0030055
## GO:1902911 GO:1902911
## GO:0061695 GO:0061695
## GO:0000307 GO:0000307
## Description
## GO:0005925 focal adhesion
## GO:0000781 chromosome, telomeric region
## GO:0030055 cell-substrate junction
## GO:1902911 protein kinase complex
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GO:0000307 cyclin-dependent protein kinase holoenzyme complex
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 16/125 421/19894 9.238717e-09 1.435092e-06 8.838270e-07
## GO:0000781 11/125 173/19894 1.230305e-08 1.435092e-06 8.838270e-07
## GO:0030055 16/125 431/19894 1.285157e-08 1.435092e-06 8.838270e-07
## GO:1902911 9/125 150/19894 4.499346e-07 3.768202e-05 2.320715e-05
## GO:0061695 12/125 308/19894 5.669862e-07 3.798808e-05 2.339564e-05
## GO:0000307 6/125 56/19894 1.369442e-06 7.646050e-05 4.708958e-05
## geneID
## GO:0005925 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/MAPK3
## GO:0000781 EZH2/PARP1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/CDK1/XRCC1/TP53BP1/RAD50
## GO:0030055 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/MAPK3
## GO:1902911 RB1/CCND1/CDKN1A/IRS1/IGF1R/PRKAA1/CCNE2/CCNE1/CDK1
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/IGF1R/PRKAA1/CCNE2/CCNE1/CDK1/PIK3CA
## GO:0000307 RB1/CCND1/CDKN1A/CCNE2/CCNE1/CDK1
## Count
## GO:0005925 16
## GO:0000781 11
## GO:0030055 16
## GO:1902911 9
## GO:0061695 12
## GO:0000307 6
## ID Description GeneRatio
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 20/130
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 20/130
## GO:0019903 GO:0019903 protein phosphatase binding 14/130
## GO:0019902 GO:0019902 phosphatase binding 15/130
## GO:0019207 GO:0019207 kinase regulator activity 16/130
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 20/130
## BgRatio pvalue p.adjust qvalue
## GO:0031625 305/18522 3.777491e-14 2.047400e-11 1.041792e-11
## GO:0044389 324/18522 1.178373e-13 3.193392e-11 1.624915e-11
## GO:0019903 142/18522 1.294257e-12 2.338291e-10 1.189808e-10
## GO:0019902 189/18522 4.697829e-12 6.365558e-10 3.239029e-10
## GO:0019207 270/18522 7.338435e-11 7.954864e-09 4.047726e-09
## GO:0140297 478/18522 1.408162e-10 1.168562e-08 5.946070e-09
## geneID
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/HSPA1A/SQSTM1
## GO:0044389 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/HSPA1A/SQSTM1
## GO:0019903 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/PTK2/RPS6KB1
## GO:0019902 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/PTK2/RPS6KB1
## GO:0019207 ERBB3/CCND1/CDKN1A/CDKN1B/EGFR/PIK3R1/PIK3R2/AKT1/CCNE2/AKT1S1/YWHAB/CAV1/CASP3/CCNE1/PIK3CA/RICTOR
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/AR/CTNNB1/EIF4E/GSK3B/ARID1A/E2F1/YAP1/SMAD4/TP53BP1
## Count
## GO:0031625 20
## GO:0044389 20
## GO:0019903 14
## GO:0019902 15
## GO:0019207 16
## GO:0140297 20
## ID Description GeneRatio BgRatio
## GO:0051402 GO:0051402 neuron apoptotic process 25/130 292/18888
## GO:0043434 GO:0043434 response to peptide hormone 28/130 438/18888
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 22/130 234/18888
## GO:0062197 GO:0062197 cellular response to chemical stress 24/130 311/18888
## GO:0018105 GO:0018105 peptidyl-serine phosphorylation 23/130 282/18888
## GO:0010038 GO:0010038 response to metal ion 25/130 360/18888
## pvalue p.adjust qvalue
## GO:0051402 1.728946e-20 7.781986e-17 3.534330e-17
## GO:0043434 1.805625e-19 4.063558e-16 1.845539e-16
## GO:0000082 5.490606e-19 8.237740e-16 3.741318e-16
## GO:0062197 1.227584e-18 1.381339e-15 6.273599e-16
## GO:0018105 2.004592e-18 1.804533e-15 8.195614e-16
## GO:0010038 2.748137e-18 2.061560e-15 9.362950e-16
## geneID
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/DIABLO/AKT1S1/BID/AXL/MSH2/CASP3/GAPDH/PIK3CA/BRAF
## GO:0043434 AKT2/ERRFI1/RB1/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/TFF1/PIK3CA/RPS6KB1/BRAF
## GO:0000082 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/ATM/CDK1/EIF4E/EIF4G1/ARID1A/CCNE2/BID/CHEK2/E2F1/CCNE1/EIF4EBP1/RPS6KB1
## GO:0062197 MET/G6PD/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/ATM/PARP1/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/PXN/BECN1/PRKCD/HSPA1A/AXL/CAV1/CASP3/PRDX1/PIK3CA
## GO:0018105 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/ATM/CDK1/EIF4G1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/TFRC/PRKCD/CAV1/RET/RPS6KB1/NEK7/RICTOR/BRAF
## GO:0010038 G6PD/BCL2/KIT/CDKN1B/EGFR/JUN/PTGS2/AKT1/PARP1/CASP8/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/TFRC/BECN1/NDRG1/EEF2K/ERCC1/CAV1/CASP3/TFF1/NEK7/BRAF
## Count
## GO:0051402 25
## GO:0043434 28
## GO:0000082 22
## GO:0062197 24
## GO:0018105 23
## GO:0010038 25
## ID
## GO:0000781 GO:0000781
## GO:0005925 GO:0005925
## GO:0030055 GO:0030055
## GO:0061695 GO:0061695
## GO:1902911 GO:1902911
## GO:0031968 GO:0031968
## Description
## GO:0000781 chromosome, telomeric region
## GO:0005925 focal adhesion
## GO:0030055 cell-substrate junction
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GO:1902911 protein kinase complex
## GO:0031968 organelle outer membrane
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0000781 12/130 173/19894 1.510211e-09 5.512271e-07 3.322465e-07
## GO:0005925 16/130 421/19894 1.635708e-08 2.761768e-06 1.664628e-06
## GO:0030055 16/130 431/19894 2.269947e-08 2.761768e-06 1.664628e-06
## GO:0061695 13/130 308/19894 1.179933e-07 1.076689e-05 6.489630e-06
## GO:1902911 9/130 150/19894 6.275122e-07 4.025720e-05 2.426461e-05
## GO:0031968 11/130 248/19894 7.132908e-07 4.025720e-05 2.426461e-05
## geneID
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/XRCC1/TP53BP1/RAD50
## GO:0005925 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1
## GO:0030055 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/CDK1/IGF1R/PRKAA1/BECN1/CCNE2/CCNE1/PIK3CA
## GO:1902911 RB1/CCND1/CDKN1A/IRS1/CDK1/IGF1R/PRKAA1/CCNE2/CCNE1
## GO:0031968 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/BECN1/BID/RPS6KB1
## Count
## GO:0000781 12
## GO:0005925 16
## GO:0030055 16
## GO:0061695 13
## GO:1902911 9
## GO:0031968 11
## ID Description GeneRatio
## GO:0019902 GO:0019902 phosphatase binding 18/138
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 21/138
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 21/138
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 24/138
## GO:0019903 GO:0019903 protein phosphatase binding 15/138
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 22/138
## BgRatio pvalue p.adjust qvalue
## GO:0019902 189/18522 3.530337e-15 1.994640e-12 1.051669e-12
## GO:0031625 305/18522 1.070939e-14 3.025403e-12 1.595136e-12
## GO:0044389 324/18522 3.537739e-14 6.662742e-12 3.512913e-12
## GO:0140297 478/18522 1.241363e-13 1.753425e-11 9.244888e-12
## GO:0019903 142/18522 1.708227e-13 1.930296e-11 1.017744e-11
## GO:0004674 427/18522 8.683081e-13 8.176568e-11 4.311073e-11
## geneID
## GO:0019902 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/PTK2/TP53/SMAD3/MAPK3/RPS6KB1
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/HSPA1A/TP53/SMAD3/SQSTM1
## GO:0044389 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/HSPA1A/TP53/SMAD3/SQSTM1
## GO:0140297 ESR1/BCL2/NCOA3/E2F1/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/AR/CTNNB1/EIF4E/GSK3B/ARID1A/CDKN2A/TP53/YAP1/SMAD3/SMAD4/MAPK3/TP53BP1
## GO:0019903 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/PTK2/TP53/RPS6KB1
## GO:0004674 AKT2/EGFR/RAF1/AKT1/ATM/CDK1/CHEK1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/ACVRL1/CHEK2/PRKCD/MAPK9/PIK3CA/MAPK3/RPS6KB1/NEK7/BRAF
## Count
## GO:0019902 18
## GO:0031625 21
## GO:0044389 21
## GO:0140297 24
## GO:0019903 15
## GO:0004674 22
## ID Description GeneRatio BgRatio
## GO:0051402 GO:0051402 neuron apoptotic process 27/138 292/18888
## GO:0043434 GO:0043434 response to peptide hormone 31/138 438/18888
## GO:0062197 GO:0062197 cellular response to chemical stress 27/138 311/18888
## GO:0010038 GO:0010038 response to metal ion 28/138 360/18888
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 24/138 234/18888
## GO:0006979 GO:0006979 response to oxidative stress 28/138 398/18888
## pvalue p.adjust qvalue
## GO:0051402 2.990530e-22 1.204328e-18 5.415104e-19
## GO:0043434 5.191068e-22 1.204328e-18 5.415104e-19
## GO:0062197 1.589685e-21 2.458712e-18 1.105528e-18
## GO:0010038 5.230037e-21 6.066843e-18 2.727877e-18
## GO:0000082 6.570800e-21 6.097702e-18 2.741753e-18
## GO:0006979 7.760224e-20 6.001240e-17 2.698380e-17
## geneID
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/AKT1S1/BID/CASP9/AXL/MSH2/CASP3/TP53/GAPDH/PIK3CA/DIABLO/BRAF
## GO:0043434 AKT2/ERRFI1/RB1/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/TFF1/XBP1/SMAD3/PIK3CA/MAPK3/RPS6KB1/BRAF
## GO:0062197 MET/G6PD/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/ATM/PARP1/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/PXN/BECN1/PRKCD/HSPA1A/AXL/CAV1/CASP3/MAPK9/TP53/PRDX1/PIK3CA/MAPK3
## GO:0010038 G6PD/BCL2/KIT/CDKN1B/EGFR/JUN/PTGS2/AKT1/PARP1/CASP8/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/BECN1/NDRG1/EEF2K/ERCC1/CASP9/CAV1/CASP3/MAPK9/TFF1/MAPK3/TFRC/NEK7/BRAF
## GO:0000082 PTEN/BCL2/E2F1/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/ATM/CDK1/EIF4E/EIF4G1/ARID1A/CCNE2/BID/CHEK2/CDKN2A/CCNE1/TP53/EIF4EBP1/RPS6KB1
## GO:0006979 MET/G6PD/BCL2/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/ATM/PARP1/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/PXN/BECN1/ERCC1/PRKCD/HSPA1A/AXL/CASP3/MAPK9/TP53/PRDX1/MAPK3/XRCC1
## Count
## GO:0051402 27
## GO:0043434 31
## GO:0062197 27
## GO:0010038 28
## GO:0000082 24
## GO:0006979 28
## ID
## GO:0005925 GO:0005925
## GO:0030055 GO:0030055
## GO:0000781 GO:0000781
## GO:0005901 GO:0005901
## GO:0061695 GO:0061695
## GO:1902911 GO:1902911
## Description
## GO:0005925 focal adhesion
## GO:0030055 cell-substrate junction
## GO:0000781 chromosome, telomeric region
## GO:0005901 caveola
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GO:1902911 protein kinase complex
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 18/138 421/19894 7.970149e-10 2.170356e-07 1.303737e-07
## GO:0030055 18/138 431/19894 1.157523e-09 2.170356e-07 1.303737e-07
## GO:0000781 12/138 173/19894 3.004464e-09 3.755580e-07 2.255983e-07
## GO:0005901 8/138 82/19894 1.011520e-07 9.482999e-06 5.696454e-06
## GO:0061695 13/138 308/19894 2.383031e-07 1.787273e-05 1.073618e-05
## GO:1902911 9/138 150/19894 1.037884e-06 5.830001e-05 3.502092e-05
## geneID
## GO:0005925 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/MAPK3/VASP
## GO:0030055 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/MAPK3/VASP
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/XRCC1/TP53BP1/RAD50
## GO:0005901 IRS1/PTGS2/CTNNB1/IGF1R/MAPK1/CAV1/MAPK3/PTCH1
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/CDK1/IGF1R/PRKAA1/BECN1/CCNE2/CCNE1/PIK3CA
## GO:1902911 RB1/CCND1/CDKN1A/IRS1/CDK1/IGF1R/PRKAA1/CCNE2/CCNE1
## Count
## GO:0005925 18
## GO:0030055 18
## GO:0000781 12
## GO:0005901 8
## GO:0061695 13
## GO:1902911 9
## ID Description GeneRatio
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 20/142
## GO:0019903 GO:0019903 protein phosphatase binding 15/142
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 20/142
## GO:0019902 GO:0019902 phosphatase binding 16/142
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 22/142
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 20/142
## BgRatio pvalue p.adjust qvalue
## GO:0031625 305/18522 2.120082e-13 7.334607e-11 3.853438e-11
## GO:0019903 142/18522 2.614833e-13 7.334607e-11 3.853438e-11
## GO:0044389 324/18522 6.535422e-13 1.222124e-10 6.420765e-11
## GO:0019902 189/18522 1.289084e-12 1.807941e-10 9.498517e-11
## GO:0140297 478/18522 1.450330e-11 1.627270e-09 8.549312e-10
## GO:0004674 427/18522 9.800004e-11 9.163003e-09 4.814037e-09
## geneID
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/HSPA1A/SQSTM1
## GO:0019903 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/PTK2/RPS6KB1/CDH2
## GO:0044389 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/HSPA1A/SQSTM1
## GO:0019902 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/PTK2/RPS6KB1/CDH2
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/AR/CTNNB1/EIF4E/GSK3B/ARID1A/E2F1/YAP1/SMAD4/TP53BP1/GATA3/VHL
## GO:0004674 AKT2/EGFR/RAF1/AKT1/ATM/CDK1/CHEK1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/CHEK2/PRKCD/PIK3CA/RPS6KB1/NEK7/BRAF/ACVRL1
## Count
## GO:0031625 20
## GO:0019903 15
## GO:0044389 20
## GO:0019902 16
## GO:0140297 22
## GO:0004674 20
## ID Description GeneRatio
## GO:0051402 GO:0051402 neuron apoptotic process 27/142
## GO:0043434 GO:0043434 response to peptide hormone 30/142
## GO:0097191 GO:0097191 extrinsic apoptotic signaling pathway 22/142
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 22/142
## GO:0062197 GO:0062197 cellular response to chemical stress 24/142
## GO:0071375 GO:0071375 cellular response to peptide hormone stimulus 24/142
## BgRatio pvalue p.adjust qvalue
## GO:0051402 292/18888 6.648362e-22 3.096142e-18 1.433247e-18
## GO:0043434 438/18888 1.614224e-20 3.758722e-17 1.739964e-17
## GO:0097191 230/18888 2.739947e-18 4.253312e-15 1.968917e-15
## GO:0000082 234/18888 3.978710e-18 4.632213e-15 2.144315e-15
## GO:0062197 311/18888 1.048821e-17 8.140599e-15 3.768395e-15
## GO:0071375 311/18888 1.048821e-17 8.140599e-15 3.768395e-15
## geneID
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/DIABLO/AKT1S1/BID/AXL/MSH2/CASP3/GAPDH/PIK3CA/BRAF/COL6A1/GATA3
## GO:0043434 AKT2/ERRFI1/RB1/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/TFF1/PIK3CA/RPS6KB1/BRAF/COL6A1/TSC1
## GO:0097191 BCL2/ERBB3/PIK3R1/BCL2L11/RAF1/FOXO3/AKT1/BCL2L1/AR/CASP8/GSK3B/PEA15/DIABLO/BID/HSPA1A/CAV1/YAP1/SMAD4/SERPINE1/RET/RPS6KB1/CTNNA1
## GO:0000082 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/ATM/CDK1/EIF4E/EIF4G1/ARID1A/CCNE2/BID/CHEK2/E2F1/CCNE1/EIF4EBP1/RPS6KB1
## GO:0062197 MET/G6PD/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/ATM/PARP1/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/PXN/BECN1/PRKCD/HSPA1A/AXL/CAV1/CASP3/PRDX1/PIK3CA
## GO:0071375 AKT2/RB1/IRS1/PIK3R1/PIK3R2/RAF1/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/PIK3CA/RPS6KB1/COL6A1
## Count
## GO:0051402 27
## GO:0043434 30
## GO:0097191 22
## GO:0000082 22
## GO:0062197 24
## GO:0071375 24
## ID
## GO:0005925 GO:0005925
## GO:0030055 GO:0030055
## GO:0000781 GO:0000781
## GO:0061695 GO:0061695
## GO:1902911 GO:1902911
## GO:0044853 GO:0044853
## Description
## GO:0005925 focal adhesion
## GO:0030055 cell-substrate junction
## GO:0000781 chromosome, telomeric region
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GO:1902911 protein kinase complex
## GO:0044853 plasma membrane raft
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 19/142 421/19894 1.719171e-10 4.879102e-08 2.783065e-08
## GO:0030055 19/142 431/19894 2.554504e-10 4.879102e-08 2.783065e-08
## GO:0000781 12/142 173/19894 4.167148e-09 5.306169e-07 3.026666e-07
## GO:0061695 13/142 308/19894 3.325123e-07 3.175492e-05 1.811317e-05
## GO:1902911 9/142 150/19894 1.318477e-06 8.401001e-05 4.791974e-05
## GO:0044853 8/142 113/19894 1.504893e-06 8.401001e-05 4.791974e-05
## geneID
## GO:0005925 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/TGM2/CDH2/CTNNA1
## GO:0030055 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/TGM2/CDH2/CTNNA1
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/XRCC1/TP53BP1/RAD50
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/CDK1/IGF1R/PRKAA1/BECN1/CCNE2/CCNE1/PIK3CA
## GO:1902911 RB1/CCND1/CDKN1A/IRS1/CDK1/IGF1R/PRKAA1/CCNE2/CCNE1
## GO:0044853 IRS1/PTGS2/CTNNB1/IGF1R/MAPK1/CAV1/CDH2/CTNNA1
## Count
## GO:0005925 19
## GO:0030055 19
## GO:0000781 12
## GO:0061695 13
## GO:1902911 9
## GO:0044853 8
## ID Description GeneRatio
## GO:0019902 GO:0019902 phosphatase binding 18/137
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 25/137
## GO:0019903 GO:0019903 protein phosphatase binding 15/137
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 21/137
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 18/137
## GO:0019207 GO:0019207 kinase regulator activity 17/137
## BgRatio pvalue p.adjust qvalue
## GO:0019902 189/18522 3.097054e-15 1.709574e-12 9.160761e-13
## GO:0140297 478/18522 1.194408e-14 3.296565e-12 1.766466e-12
## GO:0019903 142/18522 1.532438e-13 2.819686e-11 1.510930e-11
## GO:0004674 427/18522 6.306427e-12 8.702869e-10 4.663437e-10
## GO:0031625 305/18522 1.155129e-11 1.275263e-09 6.833501e-10
## GO:0019207 270/18522 1.615466e-11 1.486229e-09 7.963965e-10
## geneID
## GO:0019902 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/MAPT/MAPK1/MAPK8/PXN/YWHAE/PTK2/CTNNB1/SMAD3/MAPK3/RPS6KB1/CDH2
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/AR/EIF4E/GSK3B/ARID1A/E2F1/CDKN2A/YAP1/CTNNB1/SMAD3/SMAD4/MAPK3/TP53BP1/GATA3/VHL
## GO:0019903 MET/BCL2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/MAPT/MAPK8/PXN/YWHAE/PTK2/CTNNB1/RPS6KB1/CDH2
## GO:0004674 AKT2/EGFR/RAF1/AKT1/CHEK1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/CHEK2/PRKCD/MAPK9/CDK1/PIK3CA/MAPK3/RPS6KB1/NEK7/BRAF/ATM
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/GSK3B/YWHAE/TUBA1B/BID/CHEK2/HSPA1A/CTNNB1/SMAD3/SQSTM1
## GO:0019207 ERBB3/CCND1/CDKN1A/CDKN1B/EGFR/PIK3R1/PIK3R2/AKT1/CCNE2/AKT1S1/YWHAB/CDKN2A/CAV1/CASP3/CCNE1/PIK3CA/RICTOR
## Count
## GO:0019902 18
## GO:0140297 25
## GO:0019903 15
## GO:0004674 21
## GO:0031625 18
## GO:0019207 17
## ID Description GeneRatio
## GO:0043434 GO:0043434 response to peptide hormone 32/137
## GO:0051402 GO:0051402 neuron apoptotic process 27/137
## GO:0000082 GO:0000082 G1/S transition of mitotic cell cycle 23/137
## GO:0062197 GO:0062197 cellular response to chemical stress 25/137
## GO:0071375 GO:0071375 cellular response to peptide hormone stimulus 25/137
## GO:0018105 GO:0018105 peptidyl-serine phosphorylation 24/137
## BgRatio pvalue p.adjust qvalue
## GO:0043434 438/18888 3.011422e-23 1.351526e-19 6.102091e-20
## GO:0051402 292/18888 2.438584e-22 5.472182e-19 2.470671e-19
## GO:0000082 234/18888 1.018094e-19 1.523069e-16 6.876600e-17
## GO:0062197 311/18888 3.085904e-19 2.769907e-16 1.250603e-16
## GO:0071375 311/18888 3.085904e-19 2.769907e-16 1.250603e-16
## GO:0018105 282/18888 4.525460e-19 3.363408e-16 1.518567e-16
## geneID
## GO:0043434 ERRFI1/AKT2/RB1/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/TFF1/SMAD3/PIK3CA/MAPK3/RPS6KB1/BRAF/COL6A1/TSC1
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/PARP1/XIAP/GSK3B/AKT1S1/BID/CASP9/AXL/MSH2/CASP3/CTNNB1/GAPDH/PIK3CA/DIABLO/BRAF/COL6A1/GATA3/ATM
## GO:0000082 PTEN/BCL2/RB1/CCND1/CDKN1A/CDKN1B/MYC/EGFR/EZH2/AKT1/EIF4E/ARID1A/CCNE2/BID/CHEK2/E2F1/CDKN2A/CCNE1/CDK1/EIF4EBP1/EIF4G1/RPS6KB1/ATM
## GO:0062197 MET/G6PD/EGFR/JUN/EZH2/PTGS2/FOXO3/AKT1/PARP1/MAPT/PRKAA1/MAPK1/MAPK8/PXN/PRKCD/HSPA1A/AXL/CAV1/CASP3/MAPK9/CDK1/PRDX1/PIK3CA/MAPK3/ATM
## GO:0071375 AKT2/RB1/IRS1/PIK3R1/PIK3R2/RAF1/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/PTK2/CAV1/PIK3CA/MAPK3/RPS6KB1/COL6A1
## GO:0018105 AKT2/PTEN/BCL2/EGFR/RAF1/PTGS2/AKT1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/PRKCD/CAV1/MAPK9/CDK1/EIF4G1/RET/RPS6KB1/TFRC/NEK7/RICTOR/BRAF/ATM
## Count
## GO:0043434 32
## GO:0051402 27
## GO:0000082 23
## GO:0062197 25
## GO:0071375 25
## GO:0018105 24
## ID
## GO:0005925 GO:0005925
## GO:0030055 GO:0030055
## GO:0000781 GO:0000781
## GO:1902911 GO:1902911
## GO:0044853 GO:0044853
## GO:0061695 GO:0061695
## Description
## GO:0005925 focal adhesion
## GO:0030055 cell-substrate junction
## GO:0000781 chromosome, telomeric region
## GO:1902911 protein kinase complex
## GO:0044853 plasma membrane raft
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 19/137 421/19894 9.134021e-11 2.544137e-08 1.503712e-08
## GO:0030055 19/137 431/19894 1.360501e-10 2.544137e-08 1.503712e-08
## GO:0000781 12/137 173/19894 2.763862e-09 3.445615e-07 2.036530e-07
## GO:1902911 9/137 150/19894 9.764082e-07 8.318736e-05 4.916787e-05
## GO:0044853 8/137 113/19894 1.147925e-06 8.318736e-05 4.916787e-05
## GO:0061695 12/137 308/19894 1.516804e-06 8.318736e-05 4.916787e-05
## geneID
## GO:0005925 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/CTNNB1/MAPK3/CDH2/TGM2
## GO:0030055 KRAS/MYH9/EGFR/PIK3R2/SHC1/YWHAZ/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/PTK2/CAV1/ANXA1/CTNNB1/MAPK3/CDH2/TGM2
## GO:0000781 EZH2/PARP1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/CDK1/XRCC1/TP53BP1/RAD50/ATM
## GO:1902911 RB1/CCND1/CDKN1A/IRS1/IGF1R/PRKAA1/CCNE2/CCNE1/CDK1
## GO:0044853 IRS1/PTGS2/IGF1R/MAPK1/CAV1/CTNNB1/MAPK3/CDH2
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/IGF1R/PRKAA1/CCNE2/CCNE1/CDK1/PIK3CA
## Count
## GO:0005925 19
## GO:0030055 19
## GO:0000781 12
## GO:1902911 9
## GO:0044853 8
## GO:0061695 12
## ID Description GeneRatio
## GO:0019902 GO:0019902 phosphatase binding 18/148
## GO:0019903 GO:0019903 protein phosphatase binding 16/148
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 21/148
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 21/148
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 24/148
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 21/148
## BgRatio pvalue p.adjust qvalue
## GO:0019902 189/18522 1.235535e-14 7.005484e-12 3.680594e-12
## GO:0019903 142/18522 2.783063e-14 7.889983e-12 4.145299e-12
## GO:0031625 305/18522 4.497766e-14 8.500779e-12 4.466203e-12
## GO:0044389 324/18522 1.471113e-13 2.085303e-11 1.095592e-11
## GO:0140297 478/18522 6.101929e-13 6.919588e-11 3.635465e-11
## GO:0004674 427/18522 2.869483e-11 2.711661e-09 1.424673e-09
## geneID
## GO:0019902 MET/MAPK14/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/RPS6KB1/TSC2/CDH2
## GO:0019903 MET/MAPK14/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/RPS6KB1/CDH2
## GO:0031625 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/HSPA1A/NFE2L2/SQSTM1
## GO:0044389 BCL2/ERBB3/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD1/HSPA1A/NFE2L2/SQSTM1
## GO:0140297 ESR1/MAPK14/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/STAT5A/STAT3/PARP1/AR/CTNNB1/EIF4E/GSK3B/ARID1A/E2F1/YAP1/SMAD4/NFE2L2/TP53BP1/GATA3/VHL
## GO:0004674 AKT2/MAPK14/EGFR/RAF1/AKT1/ATM/CDK1/CHEK1/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/CHEK2/PRKCD/PIK3CA/RPS6KB1/NEK7/BRAF/ACVRL1
## Count
## GO:0019902 18
## GO:0019903 16
## GO:0031625 21
## GO:0044389 21
## GO:0140297 24
## GO:0004674 21
## ID Description GeneRatio
## GO:0043434 GO:0043434 response to peptide hormone 33/148
## GO:0051402 GO:0051402 neuron apoptotic process 27/148
## GO:0071375 GO:0071375 cellular response to peptide hormone stimulus 26/148
## GO:0010038 GO:0010038 response to metal ion 27/148
## GO:0071214 GO:0071214 cellular response to abiotic stimulus 26/148
## GO:0104004 GO:0104004 cellular response to environmental stimulus 26/148
## BgRatio pvalue p.adjust qvalue
## GO:0043434 438/18888 3.007983e-23 1.418866e-19 6.462415e-20
## GO:0051402 292/18888 2.098897e-21 4.950248e-18 2.254657e-18
## GO:0071375 311/18888 1.588846e-19 2.498196e-16 1.137837e-16
## GO:0010038 360/18888 4.960946e-19 5.850195e-16 2.664550e-16
## GO:0071214 334/18888 9.474001e-19 7.448144e-16 3.392357e-16
## GO:0104004 334/18888 9.474001e-19 7.448144e-16 3.392357e-16
## geneID
## GO:0043434 AKT2/ERRFI1/MAPK14/RB1/PTK2/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/CAV1/TFF1/NFE2L2/PIK3CA/RPS6KB1/TSC2/BRAF/COL6A1/TSC1
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/DIABLO/AKT1S1/BID/AXL/MSH2/CASP3/GAPDH/PIK3CA/BRAF/COL6A1/GATA3
## GO:0071375 AKT2/RB1/PTK2/IRS1/PIK3R1/PIK3R2/RAF1/SHC1/AKT1/STAT5A/STAT3/PARP1/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/CAV1/NFE2L2/PIK3CA/RPS6KB1/TSC2/COL6A1
## GO:0010038 G6PD/BCL2/KIT/CDKN1B/EGFR/JUN/PTGS2/AKT1/PARP1/CASP8/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/TFRC/BECN1/NDRG1/EEF2K/ERCC1/CAV1/CASP3/TFF1/CDH1/NFE2L2/NEK7/BRAF
## GO:0071214 AKT2/PTEN/MAPK14/CDKN1A/MYC/EGFR/PIK3R1/PTGS2/BCL2L1/ATM/PARP1/CASP8/CHEK1/IGF1R/ITGA2/MAPK8/RAD51/ERCC1/CHEK2/RAB11B/PRKCD/CASP3/YAP1/PIK3CA/TP53BP1/GATA3
## GO:0104004 AKT2/PTEN/MAPK14/CDKN1A/MYC/EGFR/PIK3R1/PTGS2/BCL2L1/ATM/PARP1/CASP8/CHEK1/IGF1R/ITGA2/MAPK8/RAD51/ERCC1/CHEK2/RAB11B/PRKCD/CASP3/YAP1/PIK3CA/TP53BP1/GATA3
## Count
## GO:0043434 33
## GO:0051402 27
## GO:0071375 26
## GO:0010038 27
## GO:0071214 26
## GO:0104004 26
## ID
## GO:0005925 GO:0005925
## GO:0030055 GO:0030055
## GO:0000781 GO:0000781
## GO:0044853 GO:0044853
## GO:0005901 GO:0005901
## GO:0061695 GO:0061695
## Description
## GO:0005925 focal adhesion
## GO:0030055 cell-substrate junction
## GO:0000781 chromosome, telomeric region
## GO:0044853 plasma membrane raft
## GO:0005901 caveola
## GO:0061695 transferase complex, transferring phosphorus-containing groups
## GeneRatio BgRatio pvalue p.adjust qvalue
## GO:0005925 19/148 421/19894 3.544077e-10 1.008169e-07 5.610151e-08
## GO:0030055 19/148 431/19894 5.250880e-10 1.008169e-07 5.610151e-08
## GO:0000781 12/148 173/19894 6.677535e-09 8.547245e-07 4.756279e-07
## GO:0044853 9/148 113/19894 1.691051e-07 1.334059e-05 7.423626e-06
## GO:0005901 8/148 82/19894 1.737055e-07 1.334059e-05 7.423626e-06
## GO:0061695 13/148 308/19894 5.367077e-07 3.434929e-05 1.911433e-05
## geneID
## GO:0005925 KRAS/MYH9/PTK2/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/CAV1/ANXA1/TGM2/CTNNA1/CDH2
## GO:0030055 KRAS/MYH9/PTK2/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/HSPA1A/CAV1/ANXA1/TGM2/CTNNA1/CDH2
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/XRCC1/TP53BP1/RAD50
## GO:0044853 IRS1/PTGS2/CTNNB1/IGF1R/MAPK1/CAV1/CDH1/CTNNA1/CDH2
## GO:0005901 IRS1/PTGS2/CTNNB1/IGF1R/MAPK1/CAV1/CDH1/CTNNA1
## GO:0061695 RB1/CCND1/CDKN1A/IRS1/PIK3R1/PIK3R2/CDK1/IGF1R/PRKAA1/BECN1/CCNE2/CCNE1/PIK3CA
## Count
## GO:0005925 19
## GO:0030055 19
## GO:0000781 12
## GO:0044853 9
## GO:0005901 8
## GO:0061695 13
## ID Description GeneRatio
## GO:0019902 GO:0019902 phosphatase binding 18/147
## GO:0140297 GO:0140297 DNA-binding transcription factor binding 25/147
## GO:0031625 GO:0031625 ubiquitin protein ligase binding 20/147
## GO:0019903 GO:0019903 protein phosphatase binding 15/147
## GO:0044389 GO:0044389 ubiquitin-like protein ligase binding 20/147
## GO:0004674 GO:0004674 protein serine/threonine kinase activity 22/147
## BgRatio pvalue p.adjust qvalue
## GO:0019902 189/18522 1.094884e-14 6.197044e-12 3.227027e-12
## GO:0140297 478/18522 6.481817e-14 1.834354e-11 9.552152e-12
## GO:0031625 305/18522 4.135497e-13 6.184293e-11 3.220387e-11
## GO:0019903 142/18522 4.370525e-13 6.184293e-11 3.220387e-11
## GO:0044389 324/18522 1.268528e-12 1.435974e-10 7.477639e-11
## GO:0004674 427/18522 3.229251e-12 3.046260e-10 1.586299e-10
## geneID
## GO:0019902 MET/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK1/MAPK8/PXN/YWHAE/SMAD3/MAPK3/RPS6KB1/CDH2
## GO:0140297 ESR1/BCL2/NCOA3/RB1/MYC/JUN/ETS1/YWHAZ/VHL/STAT5A/STAT3/PARP1/AR/CTNNB1/EIF4E/GSK3B/ARID1A/E2F1/CDKN2A/YAP1/SMAD3/SMAD4/MAPK3/TP53BP1/GATA3
## GO:0031625 BCL2/ERBB3/HSPA1A/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD3/SQSTM1
## GO:0019903 MET/BCL2/PTK2/CDKN1B/EGFR/PIK3R1/PIK3R2/STAT3/CTNNB1/MAPT/MAPK8/PXN/YWHAE/RPS6KB1/CDH2
## GO:0044389 BCL2/ERBB3/HSPA1A/RB1/CDKN1A/CDKN1B/EGFR/JUN/YWHAZ/PARP1/CASP8/CTNNB1/GSK3B/YWHAE/BECN1/TUBA1B/BID/CHEK2/SMAD3/SQSTM1
## GO:0004674 AKT2/EGFR/RAF1/AKT1/ATM/CDK1/CHEK1/MTOR/GSK3B/PRKAA1/PRKCA/MAPK1/MAPK8/EEF2K/CHEK2/PRKCD/MAPK9/PIK3CA/MAPK3/RPS6KB1/NEK7/BRAF
## Count
## GO:0019902 18
## GO:0140297 25
## GO:0031625 20
## GO:0019903 15
## GO:0044389 20
## GO:0004674 22
## ID Description GeneRatio
## GO:0043434 GO:0043434 response to peptide hormone 34/147
## GO:0051402 GO:0051402 neuron apoptotic process 28/147
## GO:0010038 GO:0010038 response to metal ion 29/147
## GO:0071214 GO:0071214 cellular response to abiotic stimulus 28/147
## GO:0104004 GO:0104004 cellular response to environmental stimulus 28/147
## GO:0048732 GO:0048732 gland development 31/147
## BgRatio pvalue p.adjust qvalue
## GO:0043434 438/18888 1.762332e-24 8.311157e-21 3.706462e-21
## GO:0051402 292/18888 1.066100e-22 2.513864e-19 1.121088e-19
## GO:0010038 360/18888 2.350047e-21 3.694274e-18 1.647506e-18
## GO:0071214 334/18888 4.209904e-21 3.970781e-18 1.770818e-18
## GO:0104004 334/18888 4.209904e-21 3.970781e-18 1.770818e-18
## GO:0048732 449/18888 8.026869e-21 5.403225e-18 2.409634e-18
## geneID
## GO:0043434 AKT2/ERRFI1/RB1/PTK2/CDKN1B/IRS1/PIK3R1/PIK3R2/RAF1/PTGS2/SHC1/AKT1/STAT5A/STAT3/PARP1/MTOR/GSK3B/IGF1R/PRKAA1/PRKCA/MAPK1/PXN/EEF2K/PRKCD/CAV1/TFF1/SMAD3/PIK3CA/MAPK3/RPS6KB1/BRAF/COL6A1/TSC1/XBP1
## GO:0051402 AKT2/G6PD/BCL2/ERBB3/KRAS/RB1/CCND1/BCL2L11/FOXO3/BCL2L1/ATM/PARP1/XIAP/CASP8/CTNNB1/GSK3B/AKT1S1/BID/CASP9/AXL/MSH2/CASP3/GAPDH/PIK3CA/DIABLO/BRAF/COL6A1/GATA3
## GO:0010038 G6PD/BCL2/KIT/CDKN1B/EGFR/JUN/PTGS2/AKT1/PARP1/CASP8/CDK1/MAPT/PRKAA1/MAPK1/MAPK8/BECN1/NDRG1/EEF2K/ERCC1/CASP9/CAV1/CASP3/MAPK9/TFF1/CDH1/MAPK3/TFRC/NEK7/BRAF
## GO:0071214 AKT2/PTEN/CDKN1A/MYC/EGFR/PIK3R1/PTGS2/BCL2L1/ATM/PARP1/CASP8/CHEK1/MTOR/IGF1R/ITGA2/MAPK8/RAD51/ERCC1/CHEK2/RAB11B/PRKCD/CASP9/CASP3/YAP1/PIK3CA/MAPK3/TP53BP1/GATA3
## GO:0104004 AKT2/PTEN/CDKN1A/MYC/EGFR/PIK3R1/PTGS2/BCL2L1/ATM/PARP1/CASP8/CHEK1/MTOR/IGF1R/ITGA2/MAPK8/RAD51/ERCC1/CHEK2/RAB11B/PRKCD/CASP9/CASP3/YAP1/PIK3CA/MAPK3/TP53BP1/GATA3
## GO:0048732 ESR1/AKT2/ERRFI1/MET/NOTCH1/BCL2/CCND1/CDKN1B/EGFR/BCL2L11/EZH2/RAF1/AKT1/ATM/STAT5A/AR/CTNNB1/ITGA2/MAPK1/SRSF1/CAV1/CDH1/SMAD3/SMAD4/PIK3CA/MAPK3/FASN/BRAF/TGM2/GATA3/XBP1
## Count
## GO:0043434 34
## GO:0051402 28
## GO:0010038 29
## GO:0071214 28
## GO:0104004 28
## GO:0048732 31
## ID Description GeneRatio BgRatio
## GO:0005925 GO:0005925 focal adhesion 19/147 421/19894
## GO:0030055 GO:0030055 cell-substrate junction 19/147 431/19894
## GO:0000781 GO:0000781 chromosome, telomeric region 12/147 173/19894
## GO:0044853 GO:0044853 plasma membrane raft 9/147 113/19894
## GO:0005901 GO:0005901 caveola 8/147 82/19894
## GO:0031968 GO:0031968 organelle outer membrane 12/147 248/19894
## pvalue p.adjust qvalue
## GO:0005925 3.149553e-10 8.963731e-08 5.086328e-08
## GO:0030055 4.668610e-10 8.963731e-08 5.086328e-08
## GO:0000781 6.182315e-09 7.913363e-07 4.490313e-07
## GO:0044853 1.595723e-07 1.266136e-05 7.184491e-06
## GO:0005901 1.648615e-07 1.266136e-05 7.184491e-06
## GO:0031968 3.273993e-07 1.957302e-05 1.110640e-05
## geneID
## GO:0005925 HSPA1A/KRAS/MYH9/PTK2/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/CAV1/ANXA1/MAPK3/CDH2/TGM2
## GO:0030055 HSPA1A/KRAS/MYH9/PTK2/EGFR/PIK3R2/SHC1/YWHAZ/CTNNB1/ITGA2/MAPK1/PXN/YWHAE/YWHAB/CAV1/ANXA1/MAPK3/CDH2/TGM2
## GO:0000781 EZH2/ATM/PARP1/CDK1/CHEK1/RAD51/ERCC1/CHEK2/MSH2/XRCC1/TP53BP1/RAD50
## GO:0044853 IRS1/PTGS2/CTNNB1/IGF1R/MAPK1/CAV1/CDH1/MAPK3/CDH2
## GO:0005901 IRS1/PTGS2/CTNNB1/IGF1R/MAPK1/CAV1/CDH1/MAPK3
## GO:0031968 BCL2/KRAS/BCL2L11/RAF1/PTGS2/FOXO3/BCL2L1/CASP8/MTOR/BECN1/BID/RPS6KB1
## Count
## GO:0005925 19
## GO:0030055 19
## GO:0000781 12
## GO:0044853 9
## GO:0005901 8
## GO:0031968 12barplot(ego_MF[[1]], title = "groupGO, Molecular Function, \n RPPAArray, FDR = 0.9")
barplot(ego_MF[[2]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, FDR = 1-1e-14")
barplot(ego_MF[[3]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, FDR = 1-1e-6")
barplot(ego_MF[[4]], title = "groupGO, Molecular Function, \n miRNASeqGene, FDR = 1-1e-13")
barplot(ego_MF[[5]], title = "groupGO, Molecular Function, \n miRNASeqGene, FDR = 1-1e-6")
barplot(ego_MF[[6]], title = "groupGO, Molecular Function, \n All datasets, FDR = 1-1e-14")
barplot(ego_MF[[7]], title = "groupGO, Molecular Function, \n All datasets, FDR = 1-1e-6")
barplot(ego_MF[[8]], title = "groupGO, Molecular Function, \n RPPAArray, Surviving Patients, FDR = 0.9")
barplot(ego_MF[[9]], title = "groupGO, Molecular Function, \n RPPAArray, Deceased Patients, FDR = 0.9")
barplot(ego_MF[[10]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")
barplot(ego_MF[[11]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")
barplot(ego_MF[[12]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")
barplot(ego_MF[[13]], title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")
barplot(ego_MF[[14]], title = "groupGO, Molecular Function, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-13")
barplot(ego_MF[[15]], title = "groupGO, Molecular Function, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-13")
barplot(ego_MF[[16]], title = "groupGO, Molecular Function, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
barplot(ego_MF[[17]], title = "groupGO, Molecular Function, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
barplot(ego_MF[[18]], title = "groupGO, Molecular Function, \n All datasets, Surviving Patients, FDR = 1-1e-14")
barplot(ego_MF[[19]], title = "groupGO, Molecular Function, \n All datasets, Deceased Patients, FDR = 1-1e-14")
barplot(ego_MF[[20]], title = "groupGO, Molecular Function, \n All datasets, Surviving Patients, FDR = 1-1e-6")
barplot(ego_MF[[21]], title = "groupGO, Molecular Function, \n All datasets, Deceased Patients, FDR = 1-1e-6")
barplot(ego_BP[[1]], title = "groupGO, Biological Process, \n RPPAArray, FDR = 0.9")
barplot(ego_BP[[2]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, FDR = 1-1e-14")
barplot(ego_BP[[3]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, FDR = 1-1e-6")
barplot(ego_BP[[4]], title = "groupGO, Biological Process, \n miRNASeqGene, FDR = 1-1e-13")
barplot(ego_BP[[5]], title = "groupGO, Biological Process, \n miRNASeqGene, FDR = 1-1e-6")
barplot(ego_BP[[6]], title = "groupGO, Biological Process, \n All datasets, FDR = 1-1e-14")
barplot(ego_BP[[7]], title = "groupGO, Biological Process, \n All datasets, FDR = 1-1e-6")
barplot(ego_BP[[8]], title = "groupGO, Biological Process, \n RPPAArray, Surviving Patients, FDR = 0.9")
barplot(ego_BP[[9]], title = "groupGO, Biological Process, \n RPPAArray, Deceased Patients, FDR = 0.9")
barplot(ego_BP[[10]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")
barplot(ego_BP[[11]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")
barplot(ego_BP[[12]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")
barplot(ego_BP[[13]], title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")
barplot(ego_BP[[14]], title = "groupGO, Biological Process, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-14")
barplot(ego_BP[[15]], title = "groupGO, Biological Process, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-14")
barplot(ego_BP[[16]], title = "groupGO, Biological Process, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
barplot(ego_BP[[17]], title = "groupGO, Biological Process, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
barplot(ego_BP[[18]], title = "groupGO, Biological Process, \n All datasets, Surviving Patients, FDR = 1-1e-14")
barplot(ego_BP[[19]], title = "groupGO, Biological Process, \n All datasets, Deceased Patients, FDR = 1-1e-14")
barplot(ego_BP[[20]], title = "groupGO, Biological Process, \n All datasets, Surviving Patients, FDR = 1-1e-6")
barplot(ego_BP[[21]], title = "groupGO, Biological Process, \n All datasets, Deceased Patients, FDR = 1-1e-6")
barplot(ego_CC[[1]], title = "groupGO, Cellular Component, \n RPPAArray, FDR = 0.9")
barplot(ego_CC[[2]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, FDR = 1-1e-14")
barplot(ego_CC[[3]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, FDR = 1-1e-6")
barplot(ego_CC[[4]], title = "groupGO, Cellular Component, \n miRNASeqGene, FDR = 1-1e-13")
barplot(ego_CC[[5]], title = "groupGO, Cellular Component, \n miRNASeqGene, FDR = 1-1e-6")
barplot(ego_CC[[6]], title = "groupGO, Cellular Component, \n All datasets, FDR = 1-1e-14")
barplot(ego_CC[[7]], title = "groupGO, Cellular Component, \n All datasets, FDR = 1-1e-6")
barplot(ego_CC[[8]], title = "groupGO, Cellular Component, \n RPPAArray, Surviving Patients, FDR = 0.9")
barplot(ego_CC[[9]], title = "groupGO, Cellular Component, \n RPPAArray, Deceased Patients, FDR = 0.9")
barplot(ego_CC[[10]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")
barplot(ego_CC[[11]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")
barplot(ego_CC[[12]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")
barplot(ego_CC[[13]], title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")
barplot(ego_CC[[14]], title = "groupGO, Cellular Component, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-13")
barplot(ego_CC[[15]], title = "groupGO, Cellular Component, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-13")
barplot(ego_CC[[16]], title = "groupGO, Cellular Component, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
barplot(ego_CC[[17]], title = "groupGO, Cellular Component, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
barplot(ego_CC[[18]], title = "groupGO, Cellular Component, \n All datasets, Surviving Patients, FDR = 1-1e-14")
barplot(ego_CC[[19]], title = "groupGO, Cellular Component, \n All datasets, Deceased Patients, FDR = 1-1e-14")
barplot(ego_CC[[20]], title = "groupGO, Cellular Component, \n All datasets, Surviving Patients, FDR = 1-1e-6")
barplot(ego_CC[[21]], title = "groupGO, Cellular Component, \n All datasets, Deceased Patients, FDR = 1-1e-6")
DAG plots for ego
goplot(ego_MF[[1]]) + labs(title = "groupGO, Molecular Function, \n RPPAArray, FDR = 0.9")
goplot(ego_MF[[2]]) + labs(title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, FDR = 1-1e-14")
goplot(ego_MF[[3]]) + labs(title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, FDR = 1-1e-6")
goplot(ego_MF[[4]]) + labs(title = "groupGO, Molecular Function, \n miRNASeqGene, FDR = 1-1e-13")
goplot(ego_MF[[5]]) + labs(title = "groupGO, Molecular Function, \n miRNASeqGene, FDR = 1-1e-6")
goplot(ego_MF[[6]]) + labs(title = "groupGO, Molecular Function, \n All datasets, FDR = 1-1e-14")
goplot(ego_MF[[7]]) + labs(title = "groupGO, Molecular Function, \n All datasets, FDR = 1-1e-6")
goplot(ego_MF[[8]]) + labs(title = "groupGO, Molecular Function, \n RPPAArray, Surviving Patients, FDR = 0.9")
goplot(ego_MF[[9]]) + labs(title = "groupGO, Molecular Function, \n RPPAArray, Deceased Patients, FDR = 0.9")
goplot(ego_MF[[10]]) + labs(title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")
goplot(ego_MF[[11]]) + labs(title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")
goplot(ego_MF[[12]]) + labs(title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")
goplot(ego_MF[[13]]) + labs(title = "groupGO, Molecular Function, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")
goplot(ego_MF[[14]]) + labs(title = "groupGO, Molecular Function, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-13")
goplot(ego_MF[[15]]) + labs(title = "groupGO, Molecular Function, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-13")
goplot(ego_MF[[16]]) + labs(title = "groupGO, Molecular Function, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
goplot(ego_MF[[17]]) + labs(title = "groupGO, Molecular Function, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
goplot(ego_MF[[18]]) + labs(title = "groupGO, Molecular Function, \n All datasets, Surviving Patients, FDR = 1-1e-14")
goplot(ego_MF[[19]]) + labs(title = "groupGO, Molecular Function, \n All datasets, Deceased Patients, FDR = 1-1e-14")
goplot(ego_MF[[20]]) + labs(title = "groupGO, Molecular Function, \n All datasets, Surviving Patients, FDR = 1-1e-6")
goplot(ego_MF[[21]]) + labs(title = "groupGO, Molecular Function, \n All datasets, Deceased Patients, FDR = 1-1e-6")
goplot(ego_BP[[1]]) + labs(title = "groupGO, Biological Process, \n RPPAArray, FDR = 0.9")## Warning: ggrepel: 5 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[2]]) + labs(title = "groupGO, Biological Process, \n RNASeq2GeneNorm, FDR = 1-1e-14")## Warning: ggrepel: 10 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[3]]) + labs(title = "groupGO, Biological Process, \n RNASeq2GeneNorm, FDR = 1-1e-6")## Warning: ggrepel: 9 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[4]]) + labs(title = "groupGO, Biological Process, \n miRNASeqGene, FDR = 1-1e-13")
goplot(ego_BP[[5]]) + labs(title = "groupGO, Biological Process, \n miRNASeqGene, FDR = 1-1e-6")
goplot(ego_BP[[6]]) + labs(title = "groupGO, Biological Process, \n All datasets, FDR = 1-1e-14")
goplot(ego_BP[[7]]) + labs(title = "groupGO, Biological Process, \n All datasets, FDR = 1-1e-6")## Warning: ggrepel: 2 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[8]]) + labs(title = "groupGO, Biological Process, \n RPPAArray, Surviving Patients, FDR = 0.9")## Warning: ggrepel: 4 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[9]]) + labs(title = "groupGO, Biological Process, \n RPPAArray, Deceased Patients, FDR = 0.9")
goplot(ego_BP[[10]]) + labs(title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")## Warning: ggrepel: 10 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[11]]) + labs(title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")## Warning: ggrepel: 16 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[12]]) + labs(title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")## Warning: ggrepel: 8 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[13]]) + labs(title = "groupGO, Biological Process, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")## Warning: ggrepel: 15 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
goplot(ego_BP[[14]]) + labs(title = "groupGO, Biological Process, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-14")
goplot(ego_BP[[15]]) + labs(title = "groupGO, Biological Process, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-14")
goplot(ego_BP[[16]]) + labs(title = "groupGO, Biological Process, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
goplot(ego_BP[[17]]) + labs(title = "groupGO, Biological Process, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
goplot(ego_BP[[18]]) + labs(title = "groupGO, Biological Process, \n All datasets, Surviving Patients, FDR = 1-1e-14")
goplot(ego_BP[[19]]) + labs(title = "groupGO, Biological Process, \n All datasets, Deceased Patients, FDR = 1-1e-14")
goplot(ego_BP[[20]]) + labs(title = "groupGO, Biological Process, \n All datasets, Surviving Patients, FDR = 1-1e-6")
goplot(ego_BP[[21]]) + labs(title = "groupGO, Biological Process, \n All datasets, Deceased Patients, FDR = 1-1e-6")
goplot(ego_CC[[1]]) + labs(title = "groupGO, Cellular Component, \n RPPAArray, FDR = 0.9")
goplot(ego_CC[[2]]) + labs(title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, FDR = 1-1e-14")
goplot(ego_CC[[3]]) + labs(title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, FDR = 1-1e-6")
goplot(ego_CC[[4]]) + labs(title = "groupGO, Cellular Component, \n miRNASeqGene, FDR = 1-1e-13")
goplot(ego_CC[[5]]) + labs(title = "groupGO, Cellular Component, \n miRNASeqGene, FDR = 1-1e-6")
goplot(ego_CC[[6]]) + labs(title = "groupGO, Cellular Component, \n All datasets, FDR = 1-1e-14")
goplot(ego_CC[[7]]) + labs(title = "groupGO, Cellular Component, \n All datasets, FDR = 1-1e-6")
goplot(ego_CC[[8]]) + labs(title = "groupGO, Cellular Component, \n RPPAArray, Surviving Patients, FDR = 0.9")
goplot(ego_CC[[9]]) + labs(title = "groupGO, Cellular Component, \n RPPAArray, Deceased Patients, FDR = 0.9")
goplot(ego_CC[[10]]) + labs(title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-14")
goplot(ego_CC[[11]]) + labs(title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-14")
goplot(ego_CC[[12]]) + labs(title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Surviving Patients, FDR = 1-1e-6")
goplot(ego_CC[[13]]) + labs(title = "groupGO, Cellular Component, \n RNASeq2GeneNorm, Deceased Patients, FDR = 1-1e-6")
goplot(ego_CC[[14]]) + labs(title = "groupGO, Cellular Component, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-13")
goplot(ego_CC[[15]]) + labs(title = "groupGO, Cellular Component, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-13")
goplot(ego_CC[[16]]) + labs(title = "groupGO, Cellular Component, \n miRNASeqGene, Surviving Patients, FDR = 1-1e-6")
goplot(ego_CC[[17]]) + labs(title = "groupGO, Cellular Component, \n miRNASeqGene, Deceased Patients, FDR = 1-1e-6")
goplot(ego_CC[[18]]) + labs(title = "groupGO, Cellular Component, \n All datasets, Surviving Patients, FDR = 1-1e-14")
goplot(ego_CC[[19]]) + labs(title = "groupGO, Cellular Component, \n All datasets, Deceased Patients, FDR = 1-1e-14")
goplot(ego_CC[[20]]) + labs(title = "groupGO, Cellular Component, \n All datasets, Surviving Patients, FDR = 1-1e-6")
goplot(ego_CC[[21]]) + labs(title = "groupGO, Cellular Component, \n All datasets, Deceased Patients, FDR = 1-1e-6")
3. Export Pathway Analysis result to data
pathway = list("ggo_MF" = ggo_MF,
"ggo_BP" = ggo_BP,
"ggo_CC" = ggo_CC,
"ego_MF" = ego_MF,
"ego_BP" = ego_BP,
"ego_CC" = ego_CC)
saveRDS(pathway, file = "data/out_pathway/pathways_ggm.rds")